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ChemicalBook >> CAS DataBase List >>sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate

sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate

sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate Structure
sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate structure
CAS No.
496807-11-5
Chemical Name:
sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate
Synonyms
Beraprost impurity 27;Beraprost Impurity 10 Sodium Salt;Beraprost Sodium (Mixture of Diastereomers);Beraprost sodium (Relative stereochemistry);sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate
CBNumber:
CB53400703
Molecular Formula:
C24H31NaO5
Molecular Weight:
422.5
MDL Number:
MOL File:
496807-11-5.mol
Last updated:2024-07-02 08:55:11
Request For Quotation

sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate Properties

storage temp. Store at -20°C
solubility DMSO: 250 mg/mL (594.57 mM)
form Solid
color White to light yellow

sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0007214 Beraprost(sodium) 99.88% 496807-11-5 5mg $300 2021-12-16 Buy
ChemScene CS-0007214 Beraprost(sodium) 99.88% 496807-11-5 10mg $500 2021-12-16 Buy
ChemScene CS-0007214 Beraprost(sodium) 99.88% 496807-11-5 25mg $950 2021-12-16 Buy
Product number Packaging Price Buy
CS-0007214 5mg $300 Buy
CS-0007214 10mg $500 Buy
CS-0007214 25mg $950 Buy

sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate Chemical Properties,Uses,Production

Biological Activity

Beraprost sodium, a prostacyclin analog, is a stable and orally active PGI2 prodrug. It is an effective vasodilator, which has the potential to study pulmonary hypertension by dilating renal blood vessels and improving microcirculation.

in vitro

Beraprost sodium (0.1, 1.0, and 10.0 μM; 24 hours) treatment leads to a significant increase in the number of tube formation, BPS plays an important role on angiogenic activity. Beraprost sodium (0.1, 1.0, and 10.0 μM; 24 hours) treatment let VE-cadherin at regions of cell–cell contact becomes more abundant and the morphology of endothelial cells tends to be normal compared with those cultured under hypoxia conditions.

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in vivo

Beraprost sodium (oral adminstration; 0.6 mg/kg; once daily; 3 or 7 days) can mitigate the development of renal interstitial fibrosis, decrease renal oxidative stress through its potential vasodilation effect, and further prevent renal interstitial fibrosis .

Animal Model: 6-8-week-old C57Bl/6J Male Mice
Dosage: 0.6 mg/kg
Administration: Oral adminstration; 0.6 mg/kg; once daily; 3 or 7 days
Result: < /td> Mitigated the development of renal interstitial fibrosis.

target

prodrug of PGI2; Vasodilator

storage

Store at -20°C

sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate Preparation Products And Raw materials

Raw materials

Preparation Products

sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 10978 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7846 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
TOSUN PHARM 020-61855200 13326451905 260366801@qq.com China 7626 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Nanjing wangzhixing Pharmaceutical Technology Co., Ltd 15850510341 shiqingran@wzxchem.com China 3639 58
Guangzhou Younan Technology Co., Ltd 020-020-82000279 18988968278 sales@ubiochem.com China 4324 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
China National Standard Pharmaceutical Corporation Limited 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Aladdin Scientific 		58
TargetMol Chemicals Inc. 58
Shanghai Kewel Chemical Co., Ltd. 50
TOSUN PHARM 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Nanjing wangzhixing Pharmaceutical Technology Co., Ltd 58
Guangzhou Younan Technology Co., Ltd 58

496807-11-5(sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate)Related Search:

Beraprost Impurity 4 Beraprost methyl ester Beraprost sodium Beraprost Impurity 3 Beraprost Impurity 2
Beraprost (8S,9S,16S) Isomer Beraprost 15-R isomer Sodium Salt Beraprost (8S,9S,16R) Isomer Beraprost Impurity 1

1of2

sodium:4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate Beraprost sodium (Relative stereochemistry) Beraprost Impurity 10 Sodium Salt Beraprost impurity 27 Beraprost Sodium (Mixture of Diastereomers) 496807-11-5