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1400W

CAS No.
180001-34-7
Chemical Name:
1400W
Synonyms
1400W DIHYDROCHLORIDE;400W;1400W;W 1400;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE;N-(3-(aminomethyl)benzyl)acetimidamide;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL;Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE;N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE
CBNumber:
CB5343313
Molecular Formula:
C10H15N3
Molecular Weight:
177.25
MDL Number:
MFCD01317835
MOL File:
180001-34-7.mol
Last updated:2023-05-04 17:34:35

1400W Properties

Melting point 208-220 °C
Boiling point 301.7±44.0 °C(Predicted)
Density 1.09±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO, Methanol, Water
pka 11.33±0.50(Predicted)
form solid
color White to Off-White
FDA UNII M1VB8VP8OH

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

1400W price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1415 1400W dihydrochloride ≥99%(HPLC) 180001-34-7 10 $125 2021-12-16 Buy
Tocris 1415 1400W dihydrochloride ≥99%(HPLC) 180001-34-7 50 $526 2021-12-16 Buy
TRC W400050 W1400 180001-34-7 1mg $165 2021-12-16 Buy
Usbiological 044436 1400W dihydrochloride 180001-34-7 5mg $282 2021-12-16 Buy
Usbiological 169589 1400W Dihydrochloride 180001-34-7 5mg $286 2021-12-16 Buy
Product number Packaging Price Buy
1415 10 $125 Buy
1415 50 $526 Buy
W400050 1mg $165 Buy
044436 5mg $282 Buy
169589 5mg $286 Buy

1400W Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM

Uses

1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity.

Definition

ChEBI: N-[3-(aminomethyl)benzyl]acetamidine is an aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a geroprotector and an angiogenesis inhibitor. It is a carboxamidine, an aralkylamine and a primary amino compound.

Biological Activity

Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo .

1400W Preparation Products And Raw materials

Raw materials

Preparation Products

1400W Suppliers

Global( 61)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
Ascent Scientific 4401179829988 customerservice@ascentscientific.co.uk United Kingdom 279 60
Guangzhou Zhiya Chemdrugs Co.,Ltd 18122150900 sculk28@163.com China 646 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8012 62
Chuzhou KeMail Chemical Technology Co., Ltd 0550-5196001 15000891977 wj520wjxby@126.com China 1925 55
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. 18081075745 chemflowtech@sina.com China 1886 58
Shanghai Zeye Biotechnology Co., Ltd. 021-61998551 13122364865 sale1@shzysw.net China 9772 58

View Lastest Price from 1400W manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
400W pictures 2019-12-26 400W
180001-34-7
US $1.00 / KG 1KG 97%-99.9% 100kg Career Henan Chemical Co
  • 400W pictures
  • 400W
    180001-34-7
  • US $1.00 / KG
  • 97%-99.9%
  • Career Henan Chemical Co
1400W N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE 400W W 1400 Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]- 1400W DIHYDROCHLORIDE N-(3-(aminomethyl)benzyl)acetimidamide 180001-34-7 18001-34-7 Biochemicals and Reagents BioChemical Application Index Cell Signaling Enzymes NOS Inhibitors Enzymes, Inhibitors, and Substrates Nitric Oxide Metabolism Nitric Oxide Reagents Nitric Oxide Aromatic Building Blocks Signalling