SOYASAPONIN I
- CAS No.
- 51330-27-9
- Chemical Name:
- SOYASAPONIN I
- Synonyms
- SCM 3B;SOYASAPONIN I;Soybean saponin BB;SOYASAPONIN I USP/EP/BP;SoyasaponinⅠ(Soyasaponin Bb);SOYASAPONIN BB; SOYASAPONIN I;Soyasaponin I (Soyasaponin Bb);2)-O-b-D-galactopyranosyl-(1®Inhibitor,inhibit,Soyasaponin Bb;(3beta,22beta)-22,24-dihydroxyolean-12-en-3-yl 6-deoxy-alpha...
- CBNumber:
- CB5345670
- Molecular Formula:
- C48H78O18
- Molecular Weight:
- 943.13
- MDL Number:
- MFCD02752366
- MOL File:
- 51330-27-9.mol
- MSDS File:
- SDS
Melting point | 220-222 °C(Solv: methanol (67-56-1)) |
---|---|
Boiling point | 1024.2±65.0 °C(Predicted) |
Density | 1.41 |
storage temp. | 2-8°C |
solubility | ethanol: soluble1mg/mL, clear, colorless |
pka | 2.76±0.70(Predicted) |
form | powder |
color | White |
Stability | Hygroscopic |
InChIKey | PTDAHAWQAGSZDD-IOVCITQVSA-N |
SOYASAPONIN I price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S9951 | Soyasaponin I | 51330-27-9 | 5mg | $368 | 2024-03-01 | Buy |
Sigma-Aldrich | S9951 | Soyasaponin I | 51330-27-9 | 25mg | $1470 | 2024-03-01 | Buy |
Cayman Chemical | 25140 | Soyasaponin Bb ≥95% | 51330-27-9 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 25140 | Soyasaponin Bb ≥95% | 51330-27-9 | 5mg | $139 | 2024-03-01 | Buy |
Sigma-Aldrich | PHL83545 | Soyasaponin Bb phyproof? Reference Substance | 51330-27-9 | 10mg | $514 | 2024-03-01 | Buy |
SOYASAPONIN I Chemical Properties,Uses,Production
Description
Soyasaponin Bb is a triterpenoid saponin that has been found in soy and has enzyme inhibitory, antimetastatic, anti-inflammatory, and neuroprotective biological activities. It selectively inhibits human recombinant and porcine kidney renin (IC50s = 30 and 30 μg/ml, respectively) over bovine trypsin, human urinary kallikrein, and rabbit angiotensin converting enzyme (ACE) when used at a concentration of 100 μg/ml. Soyasaponin Bb inhibits the mouse brain sialyltransferase ST3GAL1 (Ki = 2.1 μM) and decreases levels of α2,3-linked sialic acid on the cell surface and decreases migration of B16/F10 mouse melanoma cells in vitro when used at a concentration of 75 μM. It also dose-dependently increases viability and mRNA expression of heme oxygenase-1 (HO-1) in BRL 3A immortalized rat hepatocytes subjected to alcohol-induced oxidative stress. Soyasaponin Bb (10 mg/kg per day) increases the latency to enter the dark chamber in a passive avoidance test and the percentage of spontaneous alterations in the Y-maze test in a rat model of learning and memory impairment induced by ibotenic acid .
Uses
Soyasaponin I has been used:
- to test its effect on migration and invasion of ovarian cancer cell lines
- as standard for the quantification of saponins from quinoa and fenugreek samples
- as L-15 medium supplement for Zebrafish liver cell lines
Definition
ChEBI: Soyasaponin I is a triterpenoid saponin that is composed of soyasapogenol B having an alpha-L-rhamnopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->2)-beta-D-glucopyranosiduronic acid moiety attached at the 3-position via a glycosidic linkage. It has a role as a sialyltransferase inhibitor. It is a pentacyclic triterpenoid, a triterpenoid saponin, a trisaccharide derivative and a carbohydrate acid derivative. It is functionally related to a soyasapogenol B. It is a conjugate acid of a soyasaponin I(1-).
General Description
Soyasaponin I is an oleanene-type triterpenoid aglycone and is a group B soyasaponin. It is an amphiphilic molecule and is metabolized by intestinal bacteria into sugars and aglycones.
Biochem/physiol Actions
Antioxidant and anti-inflammatory saponin found in soybean. Attenuates TNBS-induced colitis in mice. The structure consists of a glycoside moiety and triterpene derivative. Sialytransferase inhibitor and renin inhibitor.
SOYASAPONIN I Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21665 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
View Lastest Price from SOYASAPONIN I manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-27 | SOYASAPONIN I; Soybean Extract
51330-27-9
|
US $0.00 / KG | 1KG | ≥98% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | ||
2023-09-06 | Soyasaponin I
51330-27-9
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | ||
2023-02-24 | Soyasaponin Bb
51330-27-9
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
- SOYASAPONIN I; Soybean Extract
51330-27-9
- US $0.00 / KG
- ≥98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
- Soyasaponin I
51330-27-9
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
- Soyasaponin Bb
51330-27-9
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
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