ChemicalBook >> CAS DataBase List >>2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE structure

CAS No.: 106461-41-0

Chemical Name:: 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE

Synonyms: Dhmt;T 1330;2,4 Dihydro-4;5-LOX inhibitor;4-TRIAZOLE-3-ONE;Hydroxyl compound;Itraconazole Impurity 22;piperazinyl]phenyl]-2-(1-methylpropyl)-;Itraconazole Hydroxy Isobutyltriazolone;2,4-dihydro-4-[4-[4-4-(hydroxyphenyl)-1-

CBNumber:: CB5356302

Molecular Formula:: C22H27N5O2

Molecular Weight:: 393.48

MDL Number:: MFCD02093087

MOL File:: 106461-41-0.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE Properties

Melting point	177-179°C
Boiling point	587.9±60.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Solid
pka	12.18±0.30(Predicted)
color	Off-White Pale Brown
CAS DataBase Reference	106461-41-0(CAS DataBase Reference)
FDA UNII	OBT4EGVAZU

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D449140	2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one	106461-41-0	500mg	$1355	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0093971	2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 95.00%	106461-41-0	500MG	$1593.9	2021-12-16	Buy
Medical Isotopes, Inc.	9465	2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]-phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one	106461-41-0	250mg	$1640	2021-12-16	Buy
Biosynth Carbosynth	FD21988	2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one	106461-41-0	500mg	$1205	2021-12-16	Buy
Biosynth Carbosynth	FD21988	2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one	106461-41-0	25mg	$110	2021-12-16	Buy

Product number	Packaging	Price	Buy
D449140	500mg	$1355	Buy
CHM0093971	500MG	$1593.9	Buy
9465	250mg	$1640	Buy
FD21988	500mg	$1205	Buy
FD21988	25mg	$110	Buy

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE Chemical Properties,Uses,Production

Chemical Properties

Light Grey Powder

Uses

An intermediate in the synthesis of Itraconazole.

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE synthesis

Synthesis of 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE from 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE Preparation Products And Raw materials

Raw materials

Formaldehyde, [2-(1-methylpropyl)hydrazinyl]- Hydrazinecarboxaldehyde, 2-(1-methylpropylidene)- 4-([4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-CARBAMIC ACID PHENYL ESTER 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

1-(4-Methoxyphenyl)-4-(4-nitrophenyl)piperazine 1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE 1-(4-Methoxyphenyl)piperazine Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate 4-Chloronitrobenzene

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Preparation Products

Itraconazole

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE Suppliers

Global( 188)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10310	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15352	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
ANHUI WITOP BIOTECH CO., LTD	58
AFINE CHEMICALS LIMITED	58

View Lastest Price from 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	5-LOX inhibitor 106461-41-0	US $50.00-142.00 / mg		98.01%	10g	TargetMol Chemicals Inc.
	2020-02-12	2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 106461-41-0	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

5-LOX inhibitor
106461-41-0
US $50.00-142.00 / mg
98.01%
TargetMol Chemicals Inc.

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE
106461-41-0
US $7.00 / KG
99%
Career Henan Chemical Co

106461-41-0(2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE)Related Search:

trans-Itraconazole 2,4-dihydro-4-[[4-(4-hydroxyphenyl)-1-piperazinyl]-phenyl]-2-(1-methylpropyl)-3h-1,2,4-triazole-3-on HYDROXY ITRACONAZOLE Itraconazole 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

N-Desalkyl Itraconazole Itraconazole Impurity 34 Butyl Itraconazole 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl benzoate

Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole Propyl Itraconazole (1,2,4-Triazol-4-yl) Itraconazole cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol

Isopropyl Itraconazole DPUDRFOQNBKHMF-YZNIXAGQSA-N 1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE

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Itraconazole Hydroxy Isobutyltriazolone IMpurity 1-(sec-butyl)-4-(2-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol- 2-sec-butyl-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-2h-1,2,4-triazol-3(4h)-one 2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]-2-(1-Methylpropyl)-3 2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]-2-(1-Methylpropyl)-3h-1,2,4-Triazol-3-One Dhmt 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one(DHMT) 2,4-Dihydro-4[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]-Phenyl]-2-(1-Methylpropyl)-3H-1,Triazole-3-One 2,4-Dihydro-4-[4-[4-(4-Hydroxylphenyl)Piperazin-l-ylPhenyl-2-(l-Methylpropyl)-3H-1,2,4-Triazol-3-One 2,4-Dichloro-4-[[4-(4-hydroxyphenyl)-1-piperazinyl]-phen-yl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 2,4-Dihydro-4-{4-Hydroxyphenyl)-2-(1- Methyl Propyl)-3H-1,2,4-Triazole-3-One 2,4-dihydro-4-[4-[4-4-(hydroxyphenyl)-1- piperazinyl]phenyl]-2-(1-methylpropyl)- Dihydro hydroxyphenyl piperazinyl phenyl methylpropyl triazole one T 1330 2,4-DIHYDRO-4-[4-[4-(HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-2-(SEC-BUTYL)-3H-1,2,4-TRIAZOL-3-ONE 2-SEC-BUTYL-4-[4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL]-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE 2,4-DIHYDRO-4-[4-[4-(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOL-3-ONE 2,4-DIHYDRO-4-[4-[4-(4-HYDROXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE 2-butan-2-yl-4-[2-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-1,2,4-triazol-3-one 2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl)Phenyl]-2-(1-Methyl Propyl)-3H-1,2,4-Triazole-3-One. Itraconazole Hydroxy Isobutyltriazolone 2,4-DIHYDRO-4-[(4-HYDROXYPHENYL)-1-PIPER AZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2 4-TRIAZOLE-3-ONE 4-[4-[4-[4-Hydroxyphenyl]piperazin-1-yl]phenyl]-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one Itraconazole Impurity 22 2, 4 - dihydro - 4 - [[4 - (4 - hydroxy phenyl) - 1 - piperazine base] phenyl] - 2 - (1 - methyl propyl) - 3 h - 1, 4-trichlorobenzene three azole nitrogen - 3 - ketone 3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)- 2,4-DIHYDRO-4-[4-[4-(4-HYDROXYLPHENYL)PIPERAZIN-1-YL]PHEN- ,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2,4-Dihydro-4-[4-[4-(4-hydroxylphenyl)piperazin-1-yl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 4-TRIAZOLE-3-ONE 4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1 2,4 Dihydro-4 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]-phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one (IT – VII)--S 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1- piperazinyl]phenyl]-2-(1 methylpropyl)-3H-1,2,4- triazol-3-1 Hydroxyl compound 1-(sec-Butyl)-4-[2-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5(4H)-one 5-LOX inhibitor 106461-41-0 C22H27N5O2 Intermediates & Fine Chemicals Pharmaceuticals