ChemicalBook >> CAS DataBase List >>Prednisone 21-acetate
Prednisone 21-acetate
- CAS No.
- 125-10-0
- Chemical Name:
- Prednisone 21-acetate
- Synonyms
- Ferr;nisone;Cblconin;d-Corlin;delcortin;deltalone;delta-corlin;PREDNISONE ACETATE;Prendnisone acetate;Prednisone 21-acetat
- CBNumber:
- CB5360752
- Molecular Formula:
- C23H28O6
- Molecular Weight:
- 400.46
- MDL Number:
- MFCD00200229
- MOL File:
- 125-10-0.mol
Last updated:2025-04-17 18:22:24
| Melting point | 240-242°C (dec.) |
|---|---|
| alpha | D25 +186° (dioxane) |
| Boiling point | 582.0±50.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.31±0.60(Predicted) |
| color | White to Off-White |
| Water Solubility | 23mg/L(25 ºC) |
| CAS DataBase Reference | 125-10-0(CAS DataBase Reference) |
| FDA UNII | OU93QEL83U |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361-H373 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P260-P314-P501 |
Prednisone 21-acetate price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P703825 | Prednisone21-Acetate | 125-10-0 | 1g | $1070 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 72104 | Prednisone21-Acetate | 125-10-0 | 1g | $1380 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003922 | PREDNISONE ACETATE 95.00% | 125-10-0 | 1G | $1593.9 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0020675 | 1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE-21-ACETATE 95.00% | 125-10-0 | 5MG | $455.35 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003922 | PREDNISONE ACETATE 95.00% | 125-10-0 | 100MG | $704.55 | 2021-12-16 | Buy |
Prednisone 21-acetate Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Adrenocortical steroid antiinflammatory.
Definition
ChEBI: Cortancyl is a steroid ester, a 20-oxo steroid, an acetate ester, a 17alpha-hydroxy steroid, an 11-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisone.
in vivo
Prednisone acetate (5 mg/kg, Intragastric gavage, once a day for 4 weeks) induces hippocampal LTP impairment by causing neuronal lesions in the dentate gyrus, which reduced glutamic acid (Glu) and NMDAR2A, and impaired spatial memory in Hippocampal LTP impairment model mice[1].
Prednisone acetate (6 mg/kg, gavage, once a day for 15 days) reduces ocular and peripheral inflammatory responses and restores Th1/Th2 and Th17/Treg immune homeostasis through orchestrating the Notch signaling pathway in Experimental autoimmune uveitis (EAU) rats[2].
| Animal Model: | C57BL/6 mice [1] |
| Dosage: | 5 mg/kg |
| Administration: | Intragastric gavage (i.g.) |
| Result: | Significantly failed to gain weight. Decreased the population spike (%) after high-frequency stimulation. Reduced the crossing times compared with the control group. Resulted in the impairment of memory, and caused a trend of more serious impairment. Reduced the levels of Glu and gamma-aminobutyric acid (GABA) in the hippocampus. Reduced the expressions of N-methyl-D-aspartate receptors in the hippocampus. |
| Animal Model: | Experimental autoimmune uveitis [2] |
| Dosage: | 6 mg/kg |
| Administration: | gavage |
| Result: | Showed fewer manifestations in eyes from day 9 after immunization. Reduced the inflammation in EAU rats. Bound with the pocket of Notch signaling-related molecules with good affinity. Exhibited anti-inflammatory effects through inhibiting Notch signaling activation. Decreased Th1, Th17 and increased Th2, Treg frequencies in EAU. |
IC 50
IL-17; IL-10; IL-4
Prednisone 21-acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 360)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5868 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +86-18565342920; +8618565342920 | sales@chembj.net | China | 307 | 58 |
| Hebei Kangcang new material Technology Co., LTD | +8615713292910 | Nancy@kangcang.com.cn | China | 341 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +86-17396673057 | linda@tnjone.com | China | 1143 | 58 |
| Henan Suikang Pharmaceutical Co.,Ltd. | +86-18239973690 +86-18239973690 | sales@suikangpharm.com | China | 311 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
View Lastest Price from Prednisone 21-acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-27 | Prednisone 21-acetate / Dehydrocortisone acetate
125-10-0
|
US $0.00-0.00 / KG | 1KG | 99% | 500 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2025-04-15 | Prednisone 21-acetate
125-10-0
|
US $0.00-0.00 / kg | 1kg | 99.0% | 1tons | Henan Suikang Pharmaceutical Co.,Ltd. | |
 |
2025-04-02 | Prednisone Acetate
125-10-0
|
US $0.00 / kg | 1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd |
-
- Prednisone 21-acetate / Dehydrocortisone acetate
125-10-0
- US $0.00-0.00 / KG
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Prednisone 21-acetate
125-10-0
- US $0.00-0.00 / kg
- 99.0%
- Henan Suikang Pharmaceutical Co.,Ltd.
-
- Prednisone Acetate
125-10-0
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
125-10-0(Prednisone 21-acetate)Related Search:
1of4
17 ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE-21-ACETATE
1-DEHYDROCORTISONE ACETATE
1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE 21-ACETATE
1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE 21-ACETATE
[2-[(8s,9s,10s,13s,14s,17r)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate
Dehydrocortisone acetate
prednisone 21-acetate
PREDNISONE ACETATE
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione-21-acetate
17α,21-Dihydroxypregna-1,4-diene-3,11,20-trioneacetate
[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate
acetic acid [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-3,11-diketo-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester
Prednisone 21-acetat
1-Cortisone 21-Acetate
21-(Acetyloxy)-17-hydroxy-pregna-1,4-diene-3,11,20-trione
11,20-trione,21-(acetyloxy)-17-hydroxy-pregna-4-diene-3
4-diene-3,11,20-trione,17,21-dihydroxy-pregna-21-acetate
delcortin
delta’-dehydrocortisoneacetate
delta-corlin
deltalone
nisone
ACETIC ACID 2-((8S,9S,10R,13S,14S,17R)-17-HYDROXY-10,13-DIMETHYL-3,11-DIOXO-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-17-YL)-2-OXO-ETHYL ESTER
21-Acetoxy-17α-hydroxypregna-1,4-diene-3,11,20-trione
Ferr
Pregna-1,4-diene-3,11,20-trione,21-(acetyloxy)-17-hydroxy-
Cblconin
acetic acid [2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxoethyl] ester
Prednisone/ Prednisone Acetate
Prednisone EP Impurity E
Prednisone EP Impurity E (Prednisone 21-Acetate)
hot selling Prednisone 21-acetate
Prednisone 21-acetate USP/EP/BP
d-Corlin
Prednisone Impurity 6
Cortancyl (Prednisone 21-acetate)
21-Acetoxy-17a-hydroxypregna-1,4-diene-3,11,20-trione (Prednisone Acetate)
Prednisone 21-acetate / Dehydrocortisone acetate
Prendnisone acetate
Alitretinoin Impurity 22
Prednisolone Impurity 32
Prednisone acetate, Glucocorticoid
Prednisone acetate, 10 mM in DMSO
125-10-0
125-10-2
C23H28O6
40046
Intermediates & Fine Chemicals
Pharmaceuticals
Steroids
125-10-0