ChemicalBook >> CAS DataBase List >>N-Carbethoxyphthalimide

N-Carbethoxyphthalimide

CAS No.
22509-74-6
Chemical Name:
N-Carbethoxyphthalimide
Synonyms
CPI;N-ETHOXYCARBONYLPHTHALIMIDE;ETHYL 1,3-DIOXOISOINDOLINE-2-CARBOXYLATE;N-CARBOETHOXYPHTHALIMIDE;2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester;ECPT;ADIN-010;NEFKEN'S REAGENT;NEFKENS' REAGENT;N-CarbethoxyphthaL
CBNumber:
CB5382202
Molecular Formula:
C11H9NO4
Molecular Weight:
219.19
MDL Number:
MFCD00005893
MOL File:
22509-74-6.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

N-Carbethoxyphthalimide Properties

Melting point 90-92 °C(lit.)
Boiling point 360°C (rough estimate)
Density 1.3219 (rough estimate)
vapor pressure 0.003-0.006Pa at 20-25℃
refractive index 1.4950 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka -3.02±0.20(Predicted)
form Crystalline Powder
color White
Water Solubility insoluble
BRN 196340
InChIKey VRHAQNTWKSVEEC-UHFFFAOYSA-N
LogP 1.1 at 20℃ and pH6.6-6.9
CAS DataBase Reference 22509-74-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII DGO9NPX8LS
NIST Chemistry Reference 2H-isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester(22509-74-6)
EPA Substance Registry System 2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester (22509-74-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264b-P270-P301+P312-P330-P403+P233-P501c
Hazard Codes  Xn
Risk Statements  22-36/37/38-20/21/22
Safety Statements  22-24/25-36/37/39-26-36
WGK Germany  3
RTECS  NR3459500
10
TSCA  Yes
HazardClass  IRRITANT
HS Code  29251995
NFPA 704
1
2 0

N-Carbethoxyphthalimide price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C5459 N-Carbethoxyphthalimide 96% 22509-74-6 25g $61.8 2024-03-01 Buy
Sigma-Aldrich C5459 N-Carbethoxyphthalimide 96% 22509-74-6 100g $159 2024-03-01 Buy
TCI Chemical C0683 N-Ethoxycarbonylphthalimide [for Peptide Synthesis] >98.0%(N) 22509-74-6 25g $43 2024-03-01 Buy
TCI Chemical C0683 N-Ethoxycarbonylphthalimide [for Peptide Synthesis] >98.0%(N) 22509-74-6 100g $115 2024-03-01 Buy
Alfa Aesar A14822 N-(Ethoxycarbonyl)phthalimide, 97% 22509-74-6 25g $34.65 2024-03-01 Buy
Product number Packaging Price Buy
C5459 25g $61.8 Buy
C5459 100g $159 Buy
C0683 25g $43 Buy
C0683 100g $115 Buy
A14822 25g $34.65 Buy

N-Carbethoxyphthalimide Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

N-Carbethoxyphthalimide is used in the synthetic preparation of a novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.

Purification Methods

Crystallise the imide from toluene/pet ether (or *benzene/pet ether). It is partly soluble in Et2O, *benzene and CHCl3. [Heller & Jacobsohn Chem Ber 54 1112 1921, Beilstein 21/10 V 428.]

541-41-3
1074-82-4
22509-74-6
Synthesis of N-Carbethoxyphthalimide from Ethyl chloroformate and Potassium phthalimide
Global( 264)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2930 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 17453 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12841 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from N-Carbethoxyphthalimide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Carbethoxyphthalimide pictures 2023-01-31 N-Carbethoxyphthalimide
22509-74-6
US $100.00 / kg 1kg 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
N-Carbethoxyphthalimide pictures 2022-09-27 N-Carbethoxyphthalimide
22509-74-6
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
N-Carbethoxyphthalimide pictures 2019-07-06 N-Carbethoxyphthalimide
22509-74-6
US $1.00 / kg 1kg 98% 100KG Career Henan Chemical Co
1,3-dihydro-1,3-dioxo-2h-isoindole-2-carboxylicaciethylester 1,3-dioxo-2-isoindolinecarboxylicaciethylester N-(Carboethoxy)phthalimide~Nefkens Ethyl phthalimidocarboxylate N-Ethoxycarbonylphthalimide [for Peptide synthesis] N-Carbethoxyphthalimide, 98+% N-Carbethoxyphthalimide, 99+% N-Ethoxycarbonylphthalimide, Ethyl 1,3-dioxo-2-isoindolinecarboxylate, Ethyl phthalimide-N-carboxylate Ethyl 1,3-dioxo-2-isoindolinecarboxylate, Ethyl phthalimide-N-carboxylate Ethyl 1,3-dioxoisoindole-2-carboxylate 1,3-Dioxoisoindoline-2-carboxylic acid ethyl ester Phthalimidylformic acid ethyl ester N-Carbethoxyphthalim ethyl 1,3-dioxo-2,3-dihydro-1H-isoindole-2-carboxylate N-CarbethoxyphthaliMide, 99+% 50GR N-CarbethoxyphthaliMide 96% Ethyl phthalimide-N-carboxylate N-Ethoxycarbonylphthalimide [for Peptide Synthesis] Ethyl 1,3-dioxoisoindoline 2-carboxylate for synthesis 2-Isoindolinecarboxylic acid, 1,3-dioxo-, ethyl ester Ethyl 1,3-dioxo-1,3-dihydro-2H-isoindole-2-carboxylate Ethyl N-phthaloylcarbamate ethyln-phthaloylcarbamate N-Carbethoxyphtalimide N-Karbetoksi-ftalimid Phthalimide-N-carbethoxy 1,3-DIOXO-1,3-DIHYDRO-ISOINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 1,3-DIOXO-2-ISOINDOLINECARBOXYLIC ACID ETHYL ESTER LABOTEST-BB LT00451715 ETHYL 1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOLE-2-CARBOXYLATE ETHYL 1,3-DIOXO-2-ISOINDOLINECARBOXYLATE ECPT CARBETHOXYPHTHALIMIDE PHTHALIMIDE-N-CARBOXYLIC ACID ETHYL ESTER N-CARBETHOXYPHTHALIMIDE NEFKEN'S REAGENT NEFKENS' REAGENT TIMTEC-BB SBB007660 ADIN-010 N-Ethoxycarbonylphthalimide [for Peptide Synthesis]> N-CarbethoxyphthaL TIANFUCHEM--22509-74-6--CHLOROMETHYL PHENYL SULFIDE factory price 2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester ETHYL 1,3-DIOXOISOINDOLINE-2-CARBOXYLATE CPI N-CARBOETHOXYPHTHALIMIDE N-ETHOXYCARBONYLPHTHALIMIDE 22509-74-6 22599-74-6 C11H9NO4 Carbonyl Compounds Building Blocks Cyclic Imides Organic Building Blocks Protection and Derivatization Protecting and Derivatizing Reagents Others Synthetic Reagents