ARG-LYS-GLU-VAL-TYR ACETATE SALT
- CAS No.
- 105184-37-0
- Chemical Name:
- ARG-LYS-GLU-VAL-TYR ACETATE SALT
- Synonyms
- SP-5 ACETATE SALT;Splenopentin diacetate;SPLENOPENTIN ACETATE SALT;ARG-LYS-GLU-VAL-TYR ACETATE;Splenopentin diacetate salt;SP-5, Splenin Fragment 32-36;Splenin pentapeptide (32-36);ARG-LYS-GLU-VAL-TYR ACETATE SALT;SPLENIN FRAGMENT 32-36 ACETATE SALT;Thymopoietin III pentapeptide (32-36)
- CBNumber:
- CB5384574
- Molecular Formula:
- C33H55N9O11
- Molecular Weight:
- 753.84
- MDL Number:
- MFCD00133108
- MOL File:
- 105184-37-0.mol
ARG-LYS-GLU-VAL-TYR ACETATE SALT Chemical Properties,Uses,Production
Biological Activity
Splenopentin diacetate is a synthetic immunomodulatory pentapeptide corresponding to residues 32-36 of the spleen hormone spleen protein. It affects early T and B cell differentiation, thereby increasing the number of antibody-forming cells in gamma-irradiated mice.
in vitro
Splenopentin (1-100 μM) augments human NK cells and has no cytotoxicity.
Splenopentin (0.1 ng/mL-10 μg/mL; 3 h) induces phenotypic differentiation of both T- and B -cell precursor cells.
in vivo
Splenopentin (1 mg/kg; ip three times a week for 7-90 d) accelerates Langerhans cell recruitment and leads to pretreatment levels of Langerhans cell (LC) density in the skin of mice.
Splenopentin (0.01-100 μg per mouse; ip) has no demonstrable effect on neuromuscular transmission of mice.
Animal Model: | Female Balb /c/Bln mice were injected Cyclophosphamide or Dexamethasone for 5 consecutive days |
Dosage: | 1 mg /kg |
Administration: | Ip three times a week for 7-90 days |
Result: | Reached the normal number of epidermal LCs at 28 days after the beginning of Cyclophosphamide treatment. Accelerated restoration process and reached the normal LC density in the skin after 70 days in Dexamethasone treatment grops. |
ARG-LYS-GLU-VAL-TYR ACETATE SALT Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Rixing Chemical CO.,LTD | +86-13237129059 -13237129059 | sales@rixingchemi.com | CHINA | 229 | 55 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10312 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 999 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
View Lastest Price from ARG-LYS-GLU-VAL-TYR ACETATE SALT manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2022-10-12 | ARG-LYS-GLU-VAL-TYR ACETATE SALT
105184-37-0
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
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2021-07-13 | Splenopentin Acetate
105184-37-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
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2020-01-10 | Splenopentin Acetate
105184-37-0
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- ARG-LYS-GLU-VAL-TYR ACETATE SALT
105184-37-0
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Splenopentin Acetate
105184-37-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Splenopentin Acetate
105184-37-0
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co