ChemicalBook >> CAS DataBase List >>SIB 1893
SIB 1893
- CAS No.
- 6266-99-5
- Chemical Name:
- SIB 1893
- Synonyms
- SIB 1893;NSC 36665;(E/Z)-SIB-1893;(E/Z)SIB1893,(E/Z) SIB 1893;(E)-2-METHYL-6-STYRYL-PYRIDINE;2-METHYL-6-(2-PHENYLETHENYL)PYRIDINE;(E)-2-METHYL-6-(2-PHENYLETHYL)-PYRIDINE;Pyridine, 2-methyl-6-(2-phenylethenyl)-;2-Methyl-6-[(E)-2-phenylethenyl]pyridine
- CBNumber:
- CB5393055
- Molecular Formula:
- C14H13N
- Molecular Weight:
- 195.26
- MDL Number:
- MFCD02262120
- MOL File:
- 6266-99-5.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:55:11
storage temp. | 2-8°C |
---|---|
solubility | DMSO: 18 mg/mL |
form | solid |
color | White to off-white |
FDA UNII | 4X2F5X24UK |
SIB 1893 price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Tocris | 1214 | SIB 1893 | 6266-99-5 | 10 | $118 | 2021-12-16 | Buy |
Tocris | 1214 | SIB 1893 | 6266-99-5 | 50 | $495 | 2021-12-16 | Buy |
TRC | S411003 | SIB 1893 | 6266-99-5 | 10mg | $80 | 2021-12-16 | Buy |
Usbiological | 256664 | SIB 1893 | 6266-99-5 | 10mg | $389 | 2021-12-16 | Buy |
ApexBio Technology | B6635 | SIB 1893 | 6266-99-5 | 10mg | $228 | 2021-12-16 | Buy |
SIB 1893 Chemical Properties,Uses,Production
Uses
SIB 1893 is a selective antagonist of mGluR-5. SIB 1893 acts as a positive allosteric modulator of human metabotropic mGlu4 (1). Anticonvulsant (2).
Definition
ChEBI: 2-methyl-6-(2-phenylethenyl)pyridine is a member of styrenes.
Biological Activity
A highly selective non-competitive antagonist for the metabotropic glutamate mGlu 5 receptor subtype; displays an IC 50 value of 0.3 μ M? at hmGlu 5 , compared with > 100 μ M at hmGlu 1b , hmGlu 2 , hmGlu 6 , hmGlu 7 and hmGlu 8 . Centrally active upon systemic administration in vivo . Positive allosteric modulator at mGlu 4 receptors.
SIB 1893 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 41)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Hangzhou Yuhao Chemical Technology Co., Ltd | 0571-82693216 | info@yuhaochemical.com | China | 9394 | 52 |
HangZhou YuHao Chemical Technology Co., Ltd. | 0571-82693216 | info@yuhaochemical.com | China | 2028 | 58 |
AdooQ Bioscience CHINA | 025-58849295 18951903616; | info@adooq.cn | China | 2990 | 60 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
6266-99-5(SIB 1893)Related Search:
ETHYLENE
stilbazium iodide
SIB 1893
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(3-NITROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-(4-METHOXYSTYRYL)-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(3-BROMOPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(2-CHLOROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
2-[(E)-2-(4-FLUOROPHENYL)ETHENYL]-5-OXO-4-(3,4,5-TRIMETHOXYPHENYL)-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(3-CHLOROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-(3,4-DICHLOROSTYRYL)-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(4-FLUOROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(4-CHLOROPHENYL)ETHENYL]-5H-INDENO[1,2-B]PYRIDIN-5-ONE
4-(2-FLUOROPHENYL)-2-[(E)-2-(3-METHOXYPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
2-[(E)-2-(3-CHLOROPHENYL)ETHENYL]-4-(4-HEPTYLPHENYL)-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(2-FLUOROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
1of4
SIB 1893
2-METHYL-6-(2-PHENYLETHENYL)PYRIDINE
(E)-2-METHYL-6-(2-PHENYLETHYL)-PYRIDINE
(E)-2-METHYL-6-STYRYL-PYRIDINE
2-Methyl-6-[(E)-2-phenylethenyl]pyridine
NSC 36665
Pyridine, 2-methyl-6-(2-phenylethenyl)-
(E/Z)-SIB-1893
(E/Z)SIB1893,(E/Z) SIB 1893
6266-99-5
Glutamate receptor