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S- (+)-Rolipram

S- (+)-Rolipram Structure
S- (+)-Rolipram structure
CAS No.
85416-73-5
Chemical Name:
S- (+)-Rolipram
Synonyms
(+)-Rolipram;(S)-(+)-ROLIPRAM;Rolipram (S)-(+)-;S- (+)-Rolipram (ME-3167;(+)-ROLIPRAM;(S)-ROLIPRAM;S- (+)-Rolipram USP/EP/BP;Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4）;(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone;(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
CBNumber:
CB5397417
Molecular Formula:
C16H21NO3
Molecular Weight:
275.34
MDL Number:
MFCD03093861
MOL File:
85416-73-5.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33
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S- (+)-Rolipram Properties

Melting point 133-136℃
Density 1.155
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
form White to off-white solid.
color White to Almost white
FDA UNII H6G4VMQ24K

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933.79.1500

S- (+)-Rolipram price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical R0183 (S)-(+)-Rolipram >98.0%(HPLC) 85416-73-5 10mg $178 2024-03-01 Buy
TCI Chemical R0183 (S)-(+)-Rolipram >98.0%(HPLC) 85416-73-5 50mg $622 2024-03-01 Buy
TRC R640045 S-(+)-Rolipram 85416-73-5 10mg $200 2021-12-16 Buy
ApexBio Technology A4349 S-(+)-Rolipram 85416-73-5 25mg $190 2021-12-16 Buy
AK Scientific X5034 S-(+)-Rolipram 85416-73-5 50mg $232 2021-12-16 Buy
Product number Packaging Price Buy
R0183 10mg $178 Buy
R0183 50mg $622 Buy
R640045 10mg $200 Buy
A4349 25mg $190 Buy
X5034 50mg $232 Buy

S- (+)-Rolipram Chemical Properties,Uses,Production

Uses

S-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor

Uses

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer

Definition

ChEBI: The (S)-enantiomer of rolipram.

Biological Activity

Less active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ).

storage

Room temperature

S- (+)-Rolipram synthesis

959799-63-4
85416-73-5
Synthesis of S- (+)-Rolipram from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

S- (+)-Rolipram Preparation Products And Raw materials

Raw materials

3-CYCLOPENTYLOXY-4-METHOXYBENZALDEHYDE Bromocyclopentane Isovanillin

Preparation Products

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE

S- (+)-Rolipram Suppliers

Global( 88)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569262 +86-15319487004 1015@dideu.com China 2127 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22883 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38632 58
Supplier Advantage
Hubei xin bonus chemical co. LTD 		58
career henan chemical co 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
TargetMol Chemicals Inc. 		58
Dideu Industries Group Limited 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
Alfa Chemistry 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from S- (+)-Rolipram manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(+)-Rolipram pictures 2024-11-19 (S)-(+)-Rolipram
85416-73-5
 US $44.00-137.00 / mg 99.14% 10g TargetMol Chemicals Inc.
S- (+)-Rolipram pictures 2024-11-05 S- (+)-Rolipram
85416-73-5
 US $0.00-0.00 / KG 5mg 99% HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
S- (+)-Rolipram pictures 2020-03-16 S- (+)-Rolipram
85416-73-5
 US $1.00 / KG 1KG 97%-99.9% 100KG Career Henan Chemical Co
  • S- (+)-Rolipram pictures
  • S- (+)-Rolipram
    85416-73-5
  • US $0.00-0.00 / KG
  • 99% HPLC
  • Shaanxi Dideu Medichem Co. Ltd

S- (+)-Rolipram Spectrum

S- (+)-Rolipram(85416-73-5)1HNMR

85416-73-5(S- (+)-Rolipram)Related Search:

ZARDAVERINE RO 20-1724 Roflumilast 4-(3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL)PYRROLIDIN-2-ONE ETAZOLATE
BRL 50481 Vinpocetine ZAPRINAST Cilostazol CILOSTAMIDE
AG 1295 (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE 4-[[3,4-(METHYLENEDIOXY)BENZYL]AMINO]-6-CHLOROQUINAZOLINE EHNA HYDROCHLORIDE S- (+)-Rolipram
4-(3'-Methoxyphenyl)-2-pyrrolidinone 4-(4'-Methoxyphenyl)-2-pyrrolidinone 1-(4-bromobenzyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

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(S)-(+)-ROLIPRAM (4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one Rolipram (S)-(+)- (4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE (4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone (S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone (4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone (+)-ROLIPRAM;(S)-ROLIPRAM 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4S)- (S)-(+)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one S- (+)-Rolipram USP/EP/BP S- (+)-Rolipram (ME-3167 (+)-Rolipram TNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Rolipram,Phosphodiesterase (PDE),cAMP,Inhibitor,factor,necrosis Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4） 85416-73-5 Signalling Cyclic Nucleotide related Inhibitors