ChemicalBook >> CAS DataBase List >>(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
![(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate Structure](CAS/20180703/GIF/848920-08-1.gif)
- CAS No.
- 848920-08-1
- Chemical Name:
- (tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
- Synonyms
- EP2 receptor antagonist-1;(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate;1H-Pyrrolo[2,3-b]quinoxaline-3-carboxylic acid, 2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-, (tetrahydro-2-furanyl)methyl ester
- CBNumber:
- CB54130821
- Molecular Formula:
- C24H22N4O5
- Molecular Weight:
- 446.46
- MDL Number:
- MOL File:
- 848920-08-1.mol
Last updated:2024-07-02 08:55:11
(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate Properties
| Boiling point | 620.9±55.0 °C(Predicted) |
|---|---|
| Density | 1.55±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| form | Solid |
| pka | 2.11±0.30(Predicted) |
| color | Off-white to light yellow |
(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate Chemical Properties,Uses,Production
Biological Activity
EP2 receptor antagonist-1 (compound 1) is a potent, reversible, and agonist dependent allosteric prostaglandin EP2 receptor antagonist. EP2 receptor antagonist-1 shows anti-inflammatory effects[1].
References
[1]. Jiang C, et, al. An Agonist Dependent Allosteric Antagonist of Prostaglandin EP2 Receptors. ACS Chem Neurosci. 2020 May 20;11(10):1436-1446.
(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11975 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 18470 | 58 |
| Supplier | Advantage |
|---|---|
| Aladdin Scientific | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
(tetrahydrofuran-2-yl)methyl 2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
EP2 receptor antagonist-1
1H-Pyrrolo[2,3-b]quinoxaline-3-carboxylic acid, 2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-, (tetrahydro-2-furanyl)methyl ester
848920-08-1