ANTI-CAM KINASE IIALPHA (CAMKIIALPHA)
- CAS No.
- Chemical Name:
- ANTI-CAM KINASE IIALPHA (CAMKIIALPHA)
- Synonyms
- ANTI-CAM KINASE IIALPHA (CAMKIIALPHA);Anti-CaM Kinase IIα (CaMKIIα) antibody produced in rabbit;Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse
- CBNumber:
- CB5425305
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02095961
- MOL File:
- Mol file
ANTI-CAM KINASE IIALPHA (CAMKIIALPHA) price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C6974 | Anti-CaM Kinase IIα (CaMKIIα) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 25μL | $184 | 2024-03-01 | Buy | |
Sigma-Aldrich | C6974 | Anti-CaM Kinase IIα (CaMKIIα) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 0.2mL | $196.4 | 2024-03-01 | Buy | |
Sigma-Aldrich | C265 | Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse clone 6G9, purified immunoglobulin, buffered aqueous solution | 100μL | $652 | 2024-03-01 | Buy |
ANTI-CAM KINASE IIALPHA (CAMKIIALPHA) Chemical Properties,Uses,Production
Uses
Anti-CaM Kinase IIα (CaMKIIα) antibody has been used:
- in immunolabelling
- in western blotting
- in immunoprecipitation
- in immunoblotting
Uses
Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse has been used in immunohistochemistry and western blotting.
General Description
CaM Kinase II α is a Ca2+/calmodulin-dependent kinase that belongs to the serine/threonine protein kinases family. It facilitates the regulation of NMDAR-dependent AMPA receptor trafficking to the synapses. Mouse anti-CaM kinase II α antibody reacts specifically with phosphorylated and non-phosphorylated forms of native and recombinant CaM (Ca2+/calmodulin-dependent) kinase II α subunit in rats. The product has shown no reactivity for phosphorylated or non-phosphorylated β subunit (60kD).
Biochem/physiol Actions
CaMKII is involved in many cellular functions in response to Ca2+ signaling, including synthesis and secretion of neurotransmitters, axonal transport, long term potentiation (LTP) and spatial learning, receptor function and regulation of gene expression. CaMKII plays a critical role in LTP, a cellular model of learning and memory. In the CNS, postsynaptic Ca2+ influx triggers rapid autophosphorylation and stable activation of CaMKII in a Ca2+/calmodulin dependent manner at a threonine residue in the autoinhibitory domain. Autophosphorylation of CaMKIIα at Thr286 has been shown to be required for LTP and learning.
ANTI-CAM KINASE IIALPHA (CAMKIIALPHA) Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-CAM KINASE IIALPHA (CAMKIIALPHA) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Riedel-de Haen AG | -- | United States | 6825 | 87 | |
SIGMA-RBI | -- | Switzerland | 6913 | 91 |
Supplier | Advantage |
---|---|
Riedel-de Haen AG | 87 |
SIGMA-RBI | 91 |