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HIPPEASTRINE HYDROBROMIDE

HIPPEASTRINE HYDROBROMIDE structure

CAS No.: 22352-41-6

Chemical Name:: HIPPEASTRINE HYDROBROMIDE

Synonyms: HIPPEASTRINE HBr;(+)-Hippeastrine HBr;HIPPEASTRINE HYDROBROMIDE

CBNumber:: CB5436572

Molecular Formula:: C17H18BrNO5

Molecular Weight:: 396.24

MDL Number:: MFCD00274497

MOL File:: 22352-41-6.mol

Last updated:2025-04-18 09:51:11

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HIPPEASTRINE HYDROBROMIDE Chemical Properties,Uses,Production

Description

Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.

Uses

Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC50 of 7.25?μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities[1].

Definition

ChEBI: Hippeastrine is an indole alkaloid isolated from the Amaryllidaceae family and has been shown to exhibit cytotoxic activity. It has a role as an antineoplastic agent and a metabolite. It is an indole alkaloid, a delta-lactone, a secondary alcohol and an organic heteropentacyclic compound.

References

[1] Chen GL, et al. Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I. Sci Rep. 2016;6:38284. Published 2016 Dec 6. DOI:10.1038/srep38284

HIPPEASTRINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

HIPPEASTRINE HYDROBROMIDE Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21629	55
TopScience Biochemical	00852-68527855	info@itopbiochem.com	China Hong Kong	902	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38630	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11973	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
TopScience Biochemical	58
TargetMol Chemicals Inc.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58

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HIPPEASTRINE HYDROBROMIDE HIPPEASTRINE HBr (+)-Hippeastrine HBr 22352-41-6