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2-Methylbenzimidazole

CAS No.
615-15-6
Chemical Name:
2-Methylbenzimidazole
Synonyms
2-METHYL-1H-BENZO[D]IMIDAZOLE;2-methyl-benzimidazol;MethylbenziMidazole;1H-Benzimidazole, 2-methyl-;AKOS 90363;RARECHEM AQ NN 0067;2-METHYLENZIMIDAZOLE;2-METHYLBENZIMIDAZOLE;Methyl-2-benzimidazole;1H-2-Methylbenzimidazol
CBNumber:
CB5439553
Molecular Formula:
C8H8N2
Molecular Weight:
132.16
MDL Number:
MFCD00005598
MOL File:
615-15-6.mol
MSDS File:
SDS
Last updated:2024-04-08 17:36:13

2-Methylbenzimidazole Properties

Melting point 175-177 °C (lit.)
Boiling point 234.08°C (rough estimate)
Density 1.1083 (rough estimate)
refractive index 1.6013 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Crystalline Powder
pka 6.19(at 25℃)
color Light beige to brown
Water Solubility slightly soluble
BRN 112264
InChIKey LDZYRENCLPUXAX-UHFFFAOYSA-N
CAS DataBase Reference 615-15-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII ZH8IWW7Y8B
NIST Chemistry Reference 1H-benzimidazole, 2-methyl-(615-15-6)
EPA Substance Registry System 1H-Benzimidazole, 2-methyl- (615-15-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
Hazard Codes  Xn
Risk Statements  22-37/38-41-20/21/22
Safety Statements  26-39-45-44
WGK Germany  3
RTECS  DD9100000
TSCA  Yes
HS Code  29339990
NFPA 704
1
2 0

2-Methylbenzimidazole price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M29800 2-Methylbenzimidazole 98% 615-15-6 5g $36.4 2024-03-01 Buy
Sigma-Aldrich M29800 2-Methylbenzimidazole 98% 615-15-6 100g $133 2024-03-01 Buy
TCI Chemical M0286 2-Methylbenzimidazole >98.0%(GC)(T) 615-15-6 25g $26 2024-03-01 Buy
TCI Chemical M0286 2-Methylbenzimidazole >98.0%(GC)(T) 615-15-6 250g $144 2024-03-01 Buy
Alfa Aesar A17290 2-Methylbenzimidazole, 98% 615-15-6 50g $35.65 2024-03-01 Buy
Product number Packaging Price Buy
M29800 5g $36.4 Buy
M29800 100g $133 Buy
M0286 25g $26 Buy
M0286 250g $144 Buy
A17290 50g $35.65 Buy

2-Methylbenzimidazole Chemical Properties,Uses,Production

Chemical Properties

light beige to brown crystalline powder. Soluble in alcohol, ether, hot water and sodium hydroxide solution, insoluble in benzene.

Uses

  • 2-Methylbenzimidazole is an important pharmacophore widely used in medicinal chemistry for the synthesis of various antibacterial and antifungal agents.
  • It can be used as a key precursor to synthesize substituted benzimidazo[1,2-a]quinolones.
  • It can be used in the synthesis of reversible solid-to-liquid phase transition coordination polymer crystals.
  • 2-Methylbenzimidazole also exhibits corrosion inhibition.

Definition

ChEBI: 2-Methyl-1H-benzo[d]imidazole is a member of benzimidazoles.

Preparation

2-Methylbenzimidazole is synthesized by the condensation of o-phenylenediamine with acetic acid. The mixture of o-phenylenediamine and acetic acid is heated at 100°C for 2 hours and then cooled slowly. 10% sodium hydroxide solution is added slowly to the mixture until it is slightly alkaline. The mixture is filtered and washed with cold water. The crude product is then recrystallized with water and decolorized with activated charcoal to obtain the final product. The yield is 68%.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 1163, 1989 DOI: 10.1002/jhet.5570260447
Chemical and Pharmaceutical Bulletin, 17, p. 1153, 1969 DOI: 10.1248/cpb.17.1153

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Global( 382)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
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airuikechemical co., ltd.
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ATK CHEMICAL COMPANY LIMITED
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Alchem Pharmtech,Inc.
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Wuhan Chemwish Technology Co., Ltd
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CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15319487004 1015@dideu.com China 2127 58

View Lastest Price from 2-Methylbenzimidazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methylbenzimidazole pictures 2024-11-05 2-Methylbenzimidazole
615-15-6
US $0.00-0.00 / KG 1g 99% 2000tons Shaanxi Dideu Medichem Co. Ltd
2-Methylbenzimidazole pictures 2024-10-15 2-Methylbenzimidazole
615-15-6
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
2-Methylbenzimidazole pictures 2023-09-11 2-Methylbenzimidazole
615-15-6
US $100.00 / bag 1bag 99 5000 Hebei Fengqiang Trading Co., LTD
2-METHYL-1H-BENZIMIDAZOLE 2-METHYLBENZIMIDAZOLE AKOS 90363 1H-2-Methylbenzimidazol 1H-2-Methylbenzimidazole 2-methyl-1h-benzimidazol Acetamidine, N-N'-o-phenylene- Benzimidazole, 2-methyl- Methyl-2-benzimidazole n-n’-o-phenylene-acetamidin RARECHEM AQ NN 0067 2-METHYLENZIMIDAZOLE 2-Methylbenzimidazole,98% 1H-Benzimidazole,2-methyl-(9CI) 2-Methyl-1,3-benzodiazde 2-Methyl-1H-benzoimidazole 2-Methyl-1,3-benzodiazole 2-Methylbenzimidazole Vetec(TM) reagent grade, 98% 2-Methylbenzimidazole> 2-METHYL-1H-BENZO[D]IMIDAZOLE 2-methyl-benzimidazol 1H-Benzimidazole, 2-methyl- MethylbenziMidazole 1-Butanone,1-(4-bromophenyl)-9-chloro- Boronicacid,B-(1,6-dihydro-6-oxo-7-pyridinyl)- 615-15-6 616-15-6 615-16-6 615-51-6 Heterocyclic Building Blocks Benzimidazoles Building Blocks Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines Benzimidazoles Building Blocks Heterocyclic Building Blocks BENZIMIDAZOLE