5,5-DIETHYLBARBITURIC ACID SODIUM SALT
- CAS No.
- 144-02-5
- Chemical Name:
- 5,5-DIETHYLBARBITURIC ACID SODIUM SALT
- Synonyms
- BARBITAL SODIUM;SODIUM BARBITAL;Embinal;Medinal;Thyalone;Natrinal;Soprinal;Nervoseton;BARBITAL NA;Sodiumveronal
- CBNumber:
- CB5460423
- Molecular Formula:
- C8H13N2NaO3
- Molecular Weight:
- 208.19
- MDL Number:
- MFCD00036203
- MOL File:
- 144-02-5.mol
- MSDS File:
- SDS
| Melting point | 190℃ |
|---|---|
| Density | 1.418[at 20℃] |
| vapor pressure | 0.004Pa at 90℃ |
| solubility | H2O: soluble50mg/mL, clear, colorless |
| form | Solid |
| color | Bitter crystals or powder |
| Water Solubility | 181.6g/L at 20℃ |
| Merck | 13,965 |
| BRN | 3921202 |
| InChIKey | RGHFKWPGWBFQLN-UHFFFAOYSA-M |
| CAS DataBase Reference | 144-02-5(CAS DataBase Reference) |
| FDA UNII | 275L5M93QS |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335-H361d-H371 |
| Precautionary statements | P201-P202-P301+P312-P302+P352-P305+P351+P338-P308+P311 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | 3288 |
| WGK Germany | 3 |
| RTECS | CQ3850000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29335300 |
| Toxicity | TDLo orl-rat: 121 g/kg/72W-C:NEO CRNGDP11,2149,90 |
5,5-DIETHYLBARBITURIC ACID SODIUM SALT Chemical Properties,Uses,Production
Chemical Properties
Bitter crystals or powder.
Uses
Biological buffer.
Definition
The soluble monosodium salt of barbital. It is a long-acting bar- biturate that depresses most metabolic processes at high doses.
Hazard
Poison; causes marked depression, pro- longed coma, and death; teratogen; questionable carcinogen; tumorigen; neoplastigen; mutagen.
Flammability and Explosibility
Not classified
Safety Profile
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Large doses cause marked depression (sometimes preceded by excitation), prolonged coma, and death. Experimental teratogenic and reproductive effects. Allergic skin reactions may occur on contact. Implicated in development of aplastic anemia. Questionable carcinogin with experimental tumorigenic and neoplastigenic data. A truly habit-forming drug. Other experimental reproductive effects. Mutation data reported. Combustible. When heated to decomposition it emits toxic fumes of NO, and NazO. See also BARBITURATES
Purification Methods
Crystallise it from water (3mL/g) by adding an equal volume of EtOH and cooling to 5o. Dry it under vacuum over P2O5. [Beilstein 24 III/IV 1904.]