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Loratadine Impurity I

CAS No.
133330-56-0
Chemical Name:
Loratadine Impurity I
Synonyms
Loratadine USP RC I;Loratadine Impurity K;Loratadine Impurity I;Loratadine Impurity 30;Loratadine EP Impurity K;Desloratadine impurity K;Loratadine EP Impurity 14;USP Loratadine Related Compound I;ethyl 4-(8-chloro-11H-benzo[5,6]cyclohepta;Loratadine Impurity 8/Dehydro Loratadine Isomer B
CBNumber:
CB54633221
Molecular Formula:
C22H21ClN2O2
Molecular Weight:
380.87
MDL Number:
MFCD32196654
MOL File:
133330-56-0.mol
Last updated:2023-05-15 10:43:58

Loratadine Impurity I Properties

Boiling point 539.3±50.0 °C(Predicted)
Density 1.283±0.06 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly)
pka 3.81±0.20(Predicted)
form Solid
color Off-White to Beige
Stability Light Sensitive

Loratadine Impurity I price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E902775 Ethyl4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate 133330-56-0 5mg $330 2021-12-16 Buy
American Custom Chemicals Corporation API0046186 DEHYDRO LORATADINE ISOMER B IMPURITY 95.00% 133330-56-0 5MG $459.48 2021-12-16 Buy
Medical Isotopes, Inc. 94570 Ethyl4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-ylidene)piperidine-1-carboxylate 133330-56-0 5mg $690 2021-12-16 Buy
Product number Packaging Price Buy
E902775 5mg $330 Buy
API0046186 5MG $459.48 Buy
94570 5mg $690 Buy

Loratadine Impurity I Chemical Properties,Uses,Production

Uses

Ethyl 4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate is an impurity of loratadine (L469575), which is a nonsedating-type histamine H1-receptor.

117811-16-2
133330-56-0
Synthesis of Loratadine Impurity I from 8-Chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one

Loratadine Impurity I Preparation Products And Raw materials

Global( 52)Suppliers
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CR Corporation Limited
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Zhengzhou Alfachem Co.,Ltd. 0371-53778726 18003825608 liuxiaoyan@alfachem.cn China 1958 58
Loratadine Impurity I Loratadine USP RC I Loratadine Impurity 30 Loratadine?Impurity?8/Dehydro?Loratadine?Isomer?B/Ethyl?4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate Loratadine Impurity 8/Dehydro Loratadine Isomer B Desloratadine impurity K Loratadine Impurity K ethyl 4-(8-chloro-11H-benzo[5,6]cyclohepta 1-Piperidinecarboxylic acid, 4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester Loratadine EP Impurity K 4-(8-Chloro-11H-Benzo[5,6]Cyclohepta[1,2-b]Pyridin-11-Ylidene)-1-(Ethoxycarbonyl)-Piperidine Loratadine Related Compound I (Dehydro Loratadine) USP Loratadine Related Compound I Loratadine EP Impurity 14 133330-56-0