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(11,12-DiHETE

(11,12-DiHETE Structure
(11,12-DiHETE structure
CAS No.
867350-92-3
Chemical Name:
(11,12-DiHETE
Synonyms
(11,12-DiHETE;11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-Eicosapentaenoic acid;11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-eicosatetraenoic acid;5,8,14,17-Eicosatetraenoic acid, 11,12-dihydroxy-, (5Z,8Z,14Z,17Z)-
CBNumber:
CB54665668
Molecular Formula:
C20H32O4
Molecular Weight:
336.47
MDL Number:
MOL File:
867350-92-3.mol
Last updated:2023-06-08 09:03:09
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(11,12-DiHETE Properties

Boiling point 515.8±50.0 °C(Predicted)
Density 1.040±0.06 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka 4.75±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS08
Signal word  Danger
Hazard statements  H225-H350
Precautionary statements  P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501
NFPA 704
3
0 0

(11,12-DiHETE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10466 (±)11,12-DiHETE ≥98% 867350-92-3 25μg $105 2024-03-01 Buy
Cayman Chemical 10466 (±)11,12-DiHETE ≥98% 867350-92-3 50μg $195 2024-03-01 Buy
Cayman Chemical 10466 (±)11,12-DiHETE ≥98% 867350-92-3 100μg $369 2024-03-01 Buy
Product number Packaging Price Buy
10466 25μg $105 Buy
10466 50μg $195 Buy
10466 100μg $369 Buy

(11,12-DiHETE Chemical Properties,Uses,Production

Description

(±)11(12)-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase. Plasma levels of (±)11(12)-DiHETE are increased over baseline after an oral dose of 1008 mg EPA.1

Definition

ChEBI: 11,12-DiHETE is a polyunsaturated fatty acid and a hydroxy fatty acid.

References

1. Schuchardt, J.P., Schneider, I., Willenberg, I., et al. Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA Prostaglandins Other Lipid Mediat. 109-111,23-31(2014).

(11,12-DiHETE Preparation Products And Raw materials

Raw materials

Preparation Products

(11,12-DiHETE Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1977 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3004 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12064 58
Supplier Advantage
Alfa Chemistry 		58
Yichang Zhongyitai Trading Co., Ltd. 58
Alfa Chemistry 60
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
amyjetsci 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
SHANGHAI ZZBIO CO., LTD. 58
(11,12-DiHETE 11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-eicosatetraenoic acid 11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-Eicosapentaenoic acid 5,8,14,17-Eicosatetraenoic acid, 11,12-dihydroxy-, (5Z,8Z,14Z,17Z)- 867350-92-3