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PF-06860932

PF-06860932 structure

CAS No.: 2226970-01-8

Chemical Name:: PF-06860932

Synonyms: PF-06860932;CFTR corrector 6;7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-

CBNumber:: CB54667293

Molecular Formula:: C22H13F4N9

Molecular Weight:: 479.39

MDL Number:: MFCD34470807

MOL File:: 2226970-01-8.mol

Last updated:2024-07-02 08:55:11

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PF-06860932 Properties

Boiling point	697.4±55.0 °C(Predicted)
Density	1.60±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
pka	3.23±0.30(Predicted)
form	Solid
color	White to off-white

PF-06860932 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0135420	CFTRcorrector6	2226970-01-8	5mg	$480	2021-12-16	Buy
ChemScene	CS-0135420	CFTRcorrector6	2226970-01-8	10mg	$800	2021-12-16	Buy
ChemScene	CS-0135420	CFTRcorrector6	2226970-01-8	25mg	$1550	2021-12-16	Buy
ChemScene	CS-0135420	CFTRcorrector6	2226970-01-8	50mg	$2400	2021-12-16	Buy
ChemScene	CS-0135420	CFTRcorrector6	2226970-01-8	100mg	$3600	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0135420	5mg	$480	Buy
CS-0135420	10mg	$800	Buy
CS-0135420	25mg	$1550	Buy
CS-0135420	50mg	$2400	Buy
CS-0135420	100mg	$3600	Buy

PF-06860932 Chemical Properties,Uses,Production

Biological Activity

CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1]. CFTR corrector 6 (Example 27) has EC50s of 1.25 nM and 1.27 nM for primary cystic fibrosis human bronchial epithelial (CF hBE) cells and fischer rat thyroid (FRT) cell lines[1].

References

[1]. Joseph Walter Strohbach, et al. Pyrrolopyrimidines as cftr potentiators. WO2018094137A1

PF-06860932 Preparation Products And Raw materials

Raw materials

Preparation Products

PF-06860932 Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
NINGBOBENKANGJS PHARMTECHCO., LTD	+8615990591583 15990591583		CHINA	2029	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Kaixin Chemical (Hong Kong) Limited	010-88886666-01 13112345678	loyson@tcypharm.com	China	595	55
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd.	15990591583		China	5573	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	021-59167510 18117107507	vip@med-life.cn	China	5012	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9274	58

Supplier	Advantage
NINGBOBENKANGJS PHARMTECHCO., LTD	58
Aladdin Scientific	58
Kaixin Chemical (Hong Kong) Limited	55
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	58
RD International Technology Co., Limited	58

PF-06860932 CFTR corrector 6 7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]- 2226970-01-8