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NCT-507

CAS No.
2231081-18-6
Chemical Name:
NCT-507
Synonyms
NCT-507;ALDH1A1-IN-2;Cyclopropanecarbonitrile, 1-[4-[6-chloro-3-[[4-(methylsulfonyl)-1-piperazinyl]carbonyl]-4-quinolinyl]phenyl]-
CBNumber:
CB54668270
Molecular Formula:
C25H23ClN4O3S
Molecular Weight:
494.99
MDL Number:
MOL File:
2231081-18-6.mol
Last updated:2024-07-02 08:55:11

NCT-507 Properties

Boiling point 738.3±70.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 3.60±0.27(Predicted)
form Solid
color White to off-white

NCT-507 Chemical Properties,Uses,Production

Biological Activity

ALDH1A1-IN-2 is a potent inhibitor of aldehyde dehydrogenase 1a1 (aldh1a1). Aldehyde dehydrogenases (ALDH) constitute a family of enzymes that play a critical role in oxidizing various cytotoxic xenogenic and biogenic aldehydes. ALDH1A1-IN-2 has the potential for the research of cancer, inflammation, or obesity (extracted from patent WO2019089626A1, compound 295)[1].

References

[1]. Shyh Ming YANG, et al. Substituted quinoline analogs as aldehyde dehydrogenase 1a1 (aldh1a1) inhibitors. Patent WO2019089626A1.

NCT-507 Preparation Products And Raw materials

Raw materials

Preparation Products

NCT-507 Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 23963 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5012 58
NCT-507 ALDH1A1-IN-2 Cyclopropanecarbonitrile, 1-[4-[6-chloro-3-[[4-(methylsulfonyl)-1-piperazinyl]carbonyl]-4-quinolinyl]phenyl]- 2231081-18-6