ChemicalBook >> CAS DataBase List >>GLX351322
GLX351322
- CAS No.
- 835598-94-2
- Chemical Name:
- GLX351322
- Synonyms
- CS-2871;GLX 351322;GLX-351322;GLX351322,GLX-351322,GLX 351322,NADPH Oxidase,NOX,Inhibitor,inhibit;Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate;Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate , GLX351322;4H-Cyclopenta[b]thiophene-3-carboxylic acid, 2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-, ethyl ester
- CBNumber:
- CB54672882
- Molecular Formula:
- C21H25N3O5S
- Molecular Weight:
- 431.51
- MDL Number:
- MFCD05123600
- MOL File:
- 835598-94-2.mol
Last updated:2024-11-19 23:02:33
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
HS Code | 2934999090 |
GLX351322 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML2546 | GLX351322 ≥98% (HPLC) | 835598-94-2 | 5MG | $95.3 | 2023-06-20 | Buy |
Sigma-Aldrich | SML2546 | GLX351322 ≥98% (HPLC) | 835598-94-2 | 25MG | $385 | 2023-06-20 | Buy |
ChemScene | CS-0018088 | GLX351322 99.48% | 835598-94-2 | 25mg | $500 | 2021-12-16 | Buy |
ChemScene | CS-0018088 | GLX351322 99.48% | 835598-94-2 | 5mg | $150 | 2021-12-16 | Buy |
ChemScene | CS-0018088 | GLX351322 99.48% | 835598-94-2 | 50mg | $850 | 2021-12-16 | Buy |
GLX351322 Chemical Properties,Uses,Production
Biological Activity
GLX351322 is an inhibitor of NADPH oxidase 4 (NOX4). It can inhibits tetracycline-induced hydrogen peroxide production in NOX4-overexpressing cells with IC50 of 5 μM.
in vitro
GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC 50 of 5 μM. GLX351322 shows weak activity against NOX2 in hPBMC cells ( IC 50 , 40 μM).
in vivo
GLX351322 (3.8 mg/kg/day, po) ameliorates HFD-induced hyperglycemia in mice.
target
Target | Value |
NOX4 (Cell-free assay) | 5 μM |
GLX351322 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 44)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32956 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
Chemia Biotechnology(Shanghai) Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4566 | 55 | |
Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 1004 | 55 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 27313 | 60 |
CS-2871
GLX 351322;GLX-351322
4H-Cyclopenta[b]thiophene-3-carboxylic acid, 2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-, ethyl ester
GLX351322,GLX-351322,GLX 351322,NADPH Oxidase,NOX,Inhibitor,inhibit
Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate , GLX351322
835598-94-2