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3-Furoic acid

CAS No.
488-93-7
Chemical Name:
3-Furoic acid
Synonyms
FURAN-3-CARBOXYLIC ACID;3-FURANCARBOXYLIC ACID;3-FUROIC ACID;3-Furioc Acid;3-Carboxyfuran;3-Furanoic acid;3-Furoicacid,99%;3-FUROIC ACID 99%;3-Furoic acid ,98%;TIMTEC-BB SBB004325
CBNumber:
CB5473553
Molecular Formula:
C5H4O3
Molecular Weight:
112.08
MDL Number:
MFCD00005350
MOL File:
488-93-7.mol
Last updated:2024-11-19 23:02:33

3-Furoic acid Properties

Melting point 120-122 °C (lit.)
Boiling point 229.64°C
Density 1.3220
refractive index 1.4710 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.9(at 25℃)
color Off-White to Beige
Water Solubility insoluble
BRN 108638
InChIKey IHCCAYCGZOLTEU-UHFFFAOYSA-N
LogP 1.030
CAS DataBase Reference 488-93-7(CAS DataBase Reference)
FDA UNII 88A3S7RG98
NIST Chemistry Reference 3-Furancarboxylic acid(488-93-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P302+P352-P305+P351+P338
Hazard Codes  Xi,C
Risk Statements  36/37/38-34
Safety Statements  26-36/37-45-36/37/39-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29321900
NFPA 704
0
2 0

3-Furoic acid price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 163392 3-Furoic acid 98% 488-93-7 5g $117 2024-03-01 Buy
Sigma-Aldrich 163392 3-Furoic acid 98% 488-93-7 25g $294 2024-03-01 Buy
TCI Chemical F0304 3-Furancarboxylic Acid >98.0%(T) 488-93-7 5g $89 2024-03-01 Buy
TCI Chemical F0304 3-Furancarboxylic Acid >98.0%(T) 488-93-7 25g $269 2024-03-01 Buy
Alfa Aesar L11629 3-Furoic acid, 99% 488-93-7 5g $89.65 2024-03-01 Buy
Product number Packaging Price Buy
163392 5g $117 Buy
163392 25g $294 Buy
F0304 5g $89 Buy
F0304 25g $269 Buy
L11629 5g $89.65 Buy

3-Furoic acid Chemical Properties,Uses,Production

Description

3-Furoic acid, also known as 3-carboxyfuran or 3-furoate, belongs to the class of organic compounds known as furoic acids. These are organic compounds containing a furoic acid moiety, with a structure characterized by a furan ring bearing a carboxylic acid group at the C2 or C3 carbon atom.
3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals. It is used in synthesis of furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction. It exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.

Chemical Properties

white to light yellow crystal powde

Uses

3-Furoic acid can be used as a reactant to synthesize:

  • Furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction.
  • (±)-Hyperolactone A by reacting with 2-methylbutanal.
  • Furo[2,3-b]pyridin-4-one-5-carboxylate ester derivatives as potential non-nucleoside inhibitors of human herpesvirus polymerases.

Uses

3-Furoic acid can be used as a reactant to synthesize:
Furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction.
(±)-Hyperolactone A by reacting with 2-methylbutanal.
Furo[2,3-b]pyridin-4-one-5-carboxylate ester derivatives as potential non-nucleoside inhibitors of human herpesvirus polymerases.

Uses

3-Furoic acid is used in synthesis of furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction. It exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.

Definition

ChEBI: A furoic acid carrying the carboxy group at position 3.

Synthesis Reference(s)

Tetrahedron Letters, 26, p. 1509, 1985 DOI: 10.1016/S0040-4039(00)98538-1

Biological Activity

3-Furoic acid exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.

Biochem/physiol Actions

3-Furoic acid exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.

Purification Methods

Crystallise the acid from water or aqueous EtOH, and sublime it in a vacuum. [Beilstein 18 I 439, 18 III/IV 4052, 18/6 V 196.]

Global( 436)Suppliers
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View Lastest Price from 3-Furoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Furanoic acid pictures 2024-11-19 3-Furanoic acid
488-93-7
US $30.00 / mL 99.82% 10g TargetMol Chemicals Inc.
3-Furoic acid pictures 2024-10-22 3-Furoic acid
488-93-7
US $6.00 / KG 1g 95% 10 tons Career Henan Chemica Co
3-Furoic acid pictures 2024-03-29 3-Furoic acid
488-93-7
US $35.00-1.20 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • 3-Furoic acid pictures
  • 3-Furoic acid
    488-93-7
  • US $35.00-1.20 / kg
  • 99%
  • Henan Fengda Chemical Co., Ltd
3-Furoic Acid SynonyMs 3-Furancarboxylic acid 3-Furancarboxylic acid (9CI) RARECHEM AL BO 1157 TIMTEC-BB SBB004325 3-FUROIC ACID 3-FUROIC ACID 99% 3-FURANECARBOXYLIC ACID 3-Furoic acid, GC 99% 3-Furoicacid,99% 3-Carboxyfuran 3-Furanoic acid 3-Furoic acid ,98% 3-Furoic acid, 99% 5GR 3 - furan forMic acid 3-FURANCARBOXYLIC ACID FOR SYNTHESIS Furan-3-carboxylic acid, 3-Carboxyfuran 3-FurancarboxylicAcid> 3-FURANCARBOXYLIC ACID 3-FUROIC ACID FURAN-3-CARBOXYLIC ACID RARECHEM AL BO 1157 TIMTEC-BB SBB004325 3-Furioc Acid 3-Furoic Acid pure, 98% 3-FURANCARBOXYLIC ACID FURAN-3-CARBOXYLIC ACID furane-3-carboxylic acid 488-93-7 488-63-7 C5H4O3 C5H3O3 ARYL ACID Building Blocks Furans Heterocyclic Building Blocks Building Blocks C4 to C7 Chemical Synthesis Heterocyclic Building Blocks Furans Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Furan&Benzofuran