AN7973
- CAS No.
- 1620899-32-2
- Chemical Name:
- AN7973
- Synonyms
- AN7973;AN7973,AN-7973;Benzamide, 2-chloro-N-(1,3-dihydro-1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-4-(1H-pyrazol-1-yl)-
- CBNumber:
- CB55821106
- Molecular Formula:
- C19H17BClN3O3
- Molecular Weight:
- 381.62
- MDL Number:
- MFCD32174283
- MOL File:
- 1620899-32-2.mol
AN7973 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0099022 | AN7973 99.70% | 1620899-32-2 | 5mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0099022 | AN7973 99.70% | 1620899-32-2 | 10mg | $580 | 2021-12-16 | Buy |
| ChemScene | CS-0099022 | AN7973 99.70% | 1620899-32-2 | 25mg | $1100 | 2021-12-16 | Buy |
| ChemScene | CS-0099022 | AN7973 99.70% | 1620899-32-2 | 50mg | $1700 | 2021-12-16 | Buy |
| ChemScene | CS-0099022 | AN7973 99.70% | 1620899-32-2 | 100mg | $2500 | 2021-12-16 | Buy |
AN7973 Chemical Properties,Uses,Production
Description
AN7973 is the 6-carboxamide benzoxaborole, blocks intracellular parasite development and inhibits Cryptosporidium growth. AN7973 is orally active, possesses favorable safety, stability, and PK parameters, and is an exciting drug candidate for treating cryptosporidiosis.
AN7973 (oral gavage; 5-25 mg/kg; once daily) is efficacious in murine models of both acute and chronic infection by rapidly eliminating C.parvum in vivo[1].AN7973 (oral gavage; 5 mg/kg, 10 mg/kg, 6.67 mg/kg; once daily, twice daily, three times daily) reduces C.parvum fecal shedding, diarrhea, and dehydration in a neonatal calf model (closely mimics that seen in infants) of cryptosporidiosis[1].AN7973 possesses favorable safety, stability, and PK parameters as an exciting drug candidate for treating cryptosporidiosis[1]. Animal Model: Four to five weeks NOD scid gamma mice (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ)(NSG) with chronic Cryptosporidium infection[1]
References
[1]. 1.Lunde CS, et al. Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis. Nat Commun. 2019 Jun 27; 10(1):2816.
AN7973 Preparation Products And Raw materials
Raw materials
Preparation Products
AN7973 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19884 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19703 | 58 |
