ChemicalBook >> CAS DataBase List >>4-Hydroxyindole
4-Hydroxyindole
- CAS No.
- 2380-94-1
- Chemical Name:
- 4-Hydroxyindole
- Synonyms
- 1H-INDOL-4-OL;4-Hdroxyindole;4-INDOLOL;INDOL-4-OL;1H-INDOLE-4-OL;4-HydroxyindoL;4-HYDROXYINDOLE;4-Hydroxxyindole;4-Hydroxylndole;4-Hydroxyindole>
- CBNumber:
- CB5663260
- Molecular Formula:
- C8H7NO
- Molecular Weight:
- 133.15
- MDL Number:
- MFCD00005667
- MOL File:
- 2380-94-1.mol
- MSDS File:
- SDS
Last updated:2025-01-21 19:14:50
| Melting point | 97-99 °C(lit.) |
|---|---|
| Boiling point | 245.66°C (rough estimate) |
| Density | 1.1475 (rough estimate) |
| vapor pressure | 0.019Pa at 25℃ |
| refractive index | 1.5260 (estimate) |
| storage temp. | 0-6°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.89±0.40(Predicted) |
| color | Dark Yellow to Green-Grey |
| Water Solubility | slightly soluble |
| Sensitive | Air Sensitive |
| BRN | 114905 |
| InChIKey | NLMQHXUGJIAKTH-UHFFFAOYSA-N |
| LogP | 1.57 at 25℃ |
| CAS DataBase Reference | 2380-94-1(CAS DataBase Reference) |
| EWG's Food Scores | 1-3 |
| FDA UNII | 1W4VD9085V |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
4-Hydroxyindole price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 219878 | 4-Hydroxyindole 99% | 2380-94-1 | 1g | $62.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1327157 | 4-Hydroxyindole United States Pharmacopeia (USP) Reference Standard | 2380-94-1 | 25MG | $1170 | 2024-03-01 | Buy |
| TCI Chemical | H0582 | 4-Hydroxyindole >99.0%(GC) | 2380-94-1 | 5g | $51 | 2021-12-16 | Buy |
| TCI Chemical | H0582 | 4-Hydroxyindole >99.0%(GC) | 2380-94-1 | 25g | $179 | 2021-12-16 | Buy |
| Alfa Aesar | L14352 | 4-Hydroxyindole, 98% | 2380-94-1 | 1g | $18.65 | 2024-03-01 | Buy |
4-Hydroxyindole Chemical Properties,Uses,Production
Chemical Properties
Off-White Cyrstalline Solid
Uses
4-Hydroxyindole is a Pindolol (P468000) impurity, which is a mixed adrenergic blocker and serotonin 5HT1A-receptor antagonist.
Definition
ChEBI: 4-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. It is a member of phenols and a member of hydroxyindoles.
Application
4-Hydroxyindole as simple indoles is the important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers. It effectively inhibits Abeta peptide-induced amyloid fibril formation and prevent cell death induced by the peptide in culture. It is used for the synthesis of anti-inflammatory angular pyrrolocoumarins.
Preparation
Synthesis of 4-hydroxyindole: Using resorcinol as raw material, 4-oxotetrahydrocoumarone carboxylic acid is prepared by isomerization, catalytic hydrogenation, and cyclization with ethyl bromopyruvate. It was added to methanol solution saturated with ammonia, and the reaction was heated in an autoclave to generate 4-oxotetrahydroindole. Finally, 4-hydroxyindole is obtained by dehydrogenation and isomerization.
General Description
Glucouridination of 4-hydroxyindole by human uridine 5′-diphospho-glucuronosyltransferase has been repotrted.
4-Hydroxyindole Preparation Products And Raw materials
Raw materials
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Preparation Products
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Global( 573)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Chukai Pharma Tech Co.,Ltd | +86-15151706780; +8615062531973 | 2279973922@qq.com | China | 391 | 58 |
| Junwee Chemical co., Ltd. | +86-571-85808636 +86-13958122542 | sales@junweechem.com | China | 821 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20267 | 58 |
| Hebei Ganmiao New material Technology Co., LTD | +86-17332992504 +86-17332992504 | sales8@hbganmiao.com | China | 300 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29793 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32965 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29879 | 58 |
Related articles
- What is 4-Hydroxyindole?
- 4-Hydroxyindole (1H-INDOL-4-OL; 1H-INDOLE-4-OL; 4-HYDROXY-1H-INDOLE; 4-INDOLOL; 4-HYDROXYINDOLE; INDOL-4-OL; 4-Hydroxy Indole ....
- Feb 19，2020
View Lastest Price from 4-Hydroxyindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-01-22 | 4-Hydroxyindole
2380-94-1
|
US $0.00-0.00 / kg | 1kg | 98 | 1000 | Wuhan Circle Star Chem-medical Technology Co.,Ltd | |
 |
2024-10-28 | 4-Hydroxyindole
2380-94-1
|
US $29.00 / g | 98.13% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-08-20 | 4-Hydroxyindole
2380-94-1
|
US $13.00-7.00 / kg | 1kg | 99.9% | 200ton | Hebei Ganmiao New material Technology Co., LTD |
-
- 4-Hydroxyindole
2380-94-1
- US $0.00-0.00 / kg
- 98
- Wuhan Circle Star Chem-medical Technology Co.,Ltd
-
- 4-Hydroxyindole
2380-94-1
- US $29.00 / g
- 98.13%
- TargetMol Chemicals Inc.
-
- 4-Hydroxyindole
2380-94-1
- US $13.00-7.00 / kg
- 99.9%
- Hebei Ganmiao New material Technology Co., LTD
2380-94-1(4-Hydroxyindole)Related Search:
1H-INDOLE-4-OL
4-HYDROXY-1H-INDOLE
4-INDOLOL
4-HYDROXYINDOLE
INDOL-4-OL
4-Hydroxy Indole (4-Indolol)
4-Hydroxxyindole
4-Hydroxyindole>99.0%
4-Hydroxyindole,98%
4-HYDROXYINDOLE(4OHI)
4-Hydroxyindole,99%
4-Hydroxyindole , 99.0%(GC)
1H-indol-4-ol, 4- hydroxyindole
4-Hydroxyindole≥ 99.5% (HPLC)
4-Hydroxyindole in stock Factory
1,5-Dihydro-indol-4-one
Pindolol EP Impurity E
4-Hydroxyindole>
4-HydroxyindoL
1H-INDOL-4-OL
4-Hdroxyindole
4-Hydroxylndole
1H-Indol-4-ol (9CI, ACI)
4 Hydroxyindole,4Hydroxyindole
Pindolol Impurity E
4-Hydroxyindole (25 mg) (1H-Indol-4-ol)
4-Hydroxyindole (Standard)
Indololol EP Impurity E
2380-94-1
Simple Indoles
Indoles
Building Blocks
ALCOHOL
Heterocyclic Building Blocks
Heterocycle-Indole series
Indole
Indoles
Indole Derivatives
Simple Indoles
Chiral Compound
Pyrroles & Indoles
Heterocycles
blocks
IndolesOxindoles
Indoles and derivatives
pharmacetical
Heterocycles series
Pyrroles & Indoles
API
Chemical
bc0001
2380-94-1