1-Bromo-3-fluoro-5-methylbenzene
- CAS No.
- 202865-83-6
- Chemical Name:
- 1-Bromo-3-fluoro-5-methylbenzene
- Synonyms
- Fluoro-5-bromotoluene;3-BROMO-5-FLUOROTOLUENE;3-FLUORO-5-BROMOTOLUENE;3-Bromo-5-fluorotoluene98%;3-Bromo-5-fluorotoluene 98%;3-Bromine-5-Fluoride Toluene;1-BROMO-3-FLUORO-5-METHYLBENZENE;Benzene, 1-bromo-3-fluoro-5-methyl-;3-Bromo-5-Fluorotoluene/5-Bromo-3-Fluorotoluene
- CBNumber:
- CB5684465
- Molecular Formula:
- C7H6BrF
- Molecular Weight:
- 189.02
- MDL Number:
- MFCD01861195
- MOL File:
- 202865-83-6.mol
| Boiling point | 183.4±20.0 °C(Predicted) |
|---|---|
| Density | 1.498±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Liquid |
| color | Colorless |
| InChI | InChI=1S/C7H6BrF/c1-5-2-6(8)4-7(9)3-5/h2-4H,1H3 |
| InChIKey | CTNFNUQREIIROB-UHFFFAOYSA-N |
| SMILES | C1(Br)=CC(C)=CC(F)=C1 |
| CAS DataBase Reference | 202865-83-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 10-36/37/38-36-22 | |||||||||
| Safety Statements | 16-26-36 | |||||||||
| RIDADR | 1993 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2903998090 | |||||||||
| NFPA 704 |
|
1-Bromo-3-fluoro-5-methylbenzene price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | H61544 | 3-Bromo-5-fluorotoluene, 98% | 202865-83-6 | 25g | $80.65 | 2024-03-01 | Buy |
| Alfa Aesar | H61544 | 3-Bromo-5-fluorotoluene, 98% | 202865-83-6 | 100g | $260.65 | 2024-03-01 | Buy |
| TRC | B693483 | 3-Bromo-5-fluorotoluene | 202865-83-6 | 100mg | $45 | 2021-12-16 | Buy |
| TRC | B693483 | 3-Bromo-5-fluorotoluene | 202865-83-6 | 250mg | $55 | 2021-12-16 | Buy |
| TRC | B693483 | 3-Bromo-5-fluorotoluene | 202865-83-6 | 500mg | $65 | 2021-12-16 | Buy |
1-Bromo-3-fluoro-5-methylbenzene Chemical Properties,Uses,Production
Uses
3-Bromo-5-fluorotoluene is an important halotoluene compound used as a structural component of many organic heterocyclic compounds. It has reactive groups, bromine and fluorine atoms, which can be used in substitution reactions.
Synthesis
2-Bromo-6-fluoro-4-methylaniline (11.2 g, 55 mmol), diluted hydrochloric acid (28.5 mL, 6 M) and acetonitrile (300 mL) were added to a 500 mL single-neck flask, then to the mixture in flask was added dropwise slowly a solution of sodium nitrite (5.69 g, 82.4 mmol) in water (40 mL) at 0 °C. After the addition, the reaction mixture was stirred at 0 °C for 1 h; then a solution of potassium iodide (18.3 g, 110 mmol) was added to the flask in water (30 mL). After the addition, the mixture was stirred at 0 °C for 0.5 h, then stirred at rt overnight. The reaction mixture was added saturated aqueous sodium sulfite (300 mL), and the resulting mixture was concentrated in vacuo to remove acetonitrile. The residue was extracted with ethyl acetate (100 mL x 2), combining the organic layers. The combined organic layers were washed with saturated brine (100 mL), dried over anhydrous sodium sulfate, and filtered. The filtrate was concentrated in vacuo. The residue was purified by silica-gel column chromatography (ethyl acetate/petroleum ether (v/v) = 1/100) to give 1-Bromo-3-fluoro-5-methylbenzene as a white solid (13.2 g, 76%).
1-Bromo-3-fluoro-5-methylbenzene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lianhe Aigen Pharmatech Co.,Ltd. | +undefined+undefined18918657159 | sales@lianhe-aigen.com | China | 312 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20284 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 1243 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 1-Bromo-3-fluoro-5-methylbenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-05 | 3-Fluoro-5-bromotoluene
202865-83-6
|
US $0.00-0.00 / KG | 50mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2024-04-08 | 3-Fluoro-5-bromotoluene
202865-83-6
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2019-07-12 | 3-Fluoro-5-bromotoluene
202865-83-6
|
US $1.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 3-Fluoro-5-bromotoluene
202865-83-6
- US $0.00-0.00 / KG
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-Fluoro-5-bromotoluene
202865-83-6
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 3-Fluoro-5-bromotoluene
202865-83-6
- US $1.00 / KG
- 99%
- Career Henan Chemical Co