Azamethiphos
- CAS No.
- 35575-96-3
- Chemical Name:
- Azamethiphos
- Synonyms
- PHOSPHOROTHIOATE;azametifos;Azametiphos;AZAMETHIFOS;snip;SNIP(R);ALFACRON;SNIP(TM);cga18809;Salmosan
- CBNumber:
- CB5687123
- Molecular Formula:
- C9H10ClN2O5PS
- Molecular Weight:
- 324.68
- MDL Number:
- MFCD00867611
- MOL File:
- 35575-96-3.mol
- MSDS File:
- SDS
Melting point | 88-93°C |
---|---|
Boiling point | 428.8±55.0 °C(Predicted) |
Density | 1.566±0.06 g/cm3(Predicted) |
vapor pressure | 4.9 x 10-6 Pa (20 °C) |
storage temp. | Sealed in dry,2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
Water Solubility | 1100 mg l-1 (20 °C) |
pka | 0.94±0.20(Predicted) |
form | Solid |
color | White to off-white |
CAS DataBase Reference | 35575-96-3(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 9440R8149U |
NIST Chemistry Reference | Phosphorothioic acid, s-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2h)-yl)methyl] o,o-dimethyl ester(35575-96-3) |
EPA Substance Registry System | Azamethiphos (35575-96-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06,GHS09 |
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Signal word | Danger | |||||||||
Hazard statements | H302-H317-H331-H410 | |||||||||
Precautionary statements | P261-P273-P280-P301+P312-P302+P352-P304+P340+P311 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-36-40-21-67-36/37/38 | |||||||||
Safety Statements | 26-36/37-24/25-23 | |||||||||
RIDADR | UN 1593 6.1/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TE8070000 | |||||||||
HS Code | 29349990 | |||||||||
Toxicity | LD50 orl-rat: 1180 mg/kg PEMNDP 9,44,91 | |||||||||
NFPA 704 |
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Azamethiphos price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 45331 | Azamethiphos PESTANAL | 35575-96-3 | 250mg | $67.3 | 2024-03-01 | Buy |
Alfa Aesar | H66105 | S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% | 35575-96-3 | 1g | $81.3 | 2023-06-20 | Buy |
Alfa Aesar | H66105 | S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% | 35575-96-3 | 5g | $332 | 2021-12-16 | Buy |
Alfa Aesar | H66105 | S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% | 35575-96-3 | 250mg | $27.1 | 2023-06-20 | Buy |
TRC | A801300 | Azamethiphos | 35575-96-3 | 5g | $80 | 2021-12-16 | Buy |
Azamethiphos Chemical Properties,Uses,Production
Description
Azamethiphos is an organothiophosphate insecticide. It can be used as a veterinary drug used in the salmon fish farming for controlling parasites such as salmon lice (Lepeophtheirus salmonis), a marine ectoparasitic copepod on salmonid species. Its primary target is on the acetylcholinesterase, a serine hydrolase involved in neurotransmission at cholinergic synapses and neuromuscular junctions.
References
Intorre, L, et al. "Safety of azamethiphos in eel, seabass and trout." Pharmacological Research the Official Journal of the Italian Pharmacological Society 49.2(2004):171. Kaur, K, et al. "Mechanism behind Resistance against the Organophosphate Azamethiphos in Salmon Lice (Lepeophtheirus salmonis). " Plos One 10.4(2015):e0124220.
Chemical Properties
white to light yellow crystal powde
Uses
Azamethiphos is used to control flies and other insect pests in animal houses and also public hygiene and health pests such as mosquitoes and cockroaches. It has recently been used to control sea lice in salmon.
Uses
Synergistic insecticidal and acaricidal organophosphorus compound
Definition
ChEBI: Azamethiphos is an organic thiophosphate, an organothiophosphate insecticide, an organochlorine insecticide and an organochlorine acaricide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an agrochemical. It is functionally related to an oxazolo[4,5-b]pyridin-2(3H)-one.
Safety Profile
Moderately toxic by ingestion andskin contact. When heated to decomposition it emits toxicvapors of NOx, SOx, POx, and Cl- .
Metabolic pathway
Azamethiphos is metabolised in mammals via hydrolysis, followed by opening of the oxazolinone ring and conjugation of the resultant aminopyridinol as the glucuronide and sulfate ester.
Metabolism
Azamethiphos is metabolized via the cleavage of phosphorothiolate C?S bond, followed by N-demethylation and opening of the oxazolinone ring and conjugation of the resultant aminochloropyridinol as the glucuronide and sulfate ester.
Degradation
Azamethiphos is unstable in alkalis and acids. The DT50 values at pH 5,7 and 9 were 800,260 and 4.3 hours, respectively (PM).
Toxicity evaluation
Acute oral LD50 for rats is 1180 mg/kg. Inhalation LC50 (4 h) for rats is >560 mg/m3 air. ADI is 0.025 mg/kg.
Azamethiphos Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
Hebei Mojin Biotechnology Co.,Ltd | +86-15028179902 | angelia@hbmojin.com | China | 1177 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
View Lastest Price from Azamethiphos manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | Azamethiphos
35575-96-3
|
US $39.00 / mg | 97.99% | 10g | TargetMol Chemicals Inc. | |||
2024-10-24 | Azamethiphos
35575-96-3
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | ||
2024-10-11 | Azamethiphos
35575-96-3
|
US $10.00 / KG | 1KG | 99.8% | 100tons | Hebei Chuanghai Biotechnology Co,.LTD |
- Azamethiphos
35575-96-3
- US $39.00 / mg
- 97.99%
- TargetMol Chemicals Inc.
- Azamethiphos
35575-96-3
- US $1.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
- Azamethiphos
35575-96-3
- US $10.00 / KG
- 99.8%
- Hebei Chuanghai Biotechnology Co,.LTD
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