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Azamethiphos

CAS No.
35575-96-3
Chemical Name:
Azamethiphos
Synonyms
PHOSPHOROTHIOATE;azametifos;Azametiphos;AZAMETHIFOS;snip;SNIP(R);ALFACRON;SNIP(TM);cga18809;Salmosan
CBNumber:
CB5687123
Molecular Formula:
C9H10ClN2O5PS
Molecular Weight:
324.68
MDL Number:
MFCD00867611
MOL File:
35575-96-3.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Azamethiphos Properties

Melting point 88-93°C
Boiling point 428.8±55.0 °C(Predicted)
Density 1.566±0.06 g/cm3(Predicted)
vapor pressure 4.9 x 10-6 Pa (20 °C)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
Water Solubility 1100 mg l-1 (20 °C)
pka 0.94±0.20(Predicted)
form Solid
color White to off-white
CAS DataBase Reference 35575-96-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 9440R8149U
NIST Chemistry Reference Phosphorothioic acid, s-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2h)-yl)methyl] o,o-dimethyl ester(35575-96-3)
EPA Substance Registry System Azamethiphos (35575-96-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H302-H317-H331-H410
Precautionary statements  P261-P273-P280-P301+P312-P302+P352-P304+P340+P311
Hazard Codes  Xn
Risk Statements  22-36-40-21-67-36/37/38
Safety Statements  26-36/37-24/25-23
RIDADR  UN 1593 6.1/PG 3
WGK Germany  3
RTECS  TE8070000
HS Code  29349990
Toxicity LD50 orl-rat: 1180 mg/kg PEMNDP 9,44,91
NFPA 704
1
3 0

Azamethiphos price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 45331 Azamethiphos PESTANAL 35575-96-3 250mg $67.3 2024-03-01 Buy
Alfa Aesar H66105 S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% 35575-96-3 1g $81.3 2023-06-20 Buy
Alfa Aesar H66105 S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% 35575-96-3 5g $332 2021-12-16 Buy
Alfa Aesar H66105 S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% 35575-96-3 250mg $27.1 2023-06-20 Buy
TRC A801300 Azamethiphos 35575-96-3 5g $80 2021-12-16 Buy
Product number Packaging Price Buy
45331 250mg $67.3 Buy
H66105 1g $81.3 Buy
H66105 5g $332 Buy
H66105 250mg $27.1 Buy
A801300 5g $80 Buy

Azamethiphos Chemical Properties,Uses,Production

Description

Azamethiphos is an organothiophosphate insecticide. It can be used as a veterinary drug used in the salmon fish farming for controlling parasites such as salmon lice (Lepeophtheirus salmonis), a marine ectoparasitic copepod on salmonid species. Its primary target is on the acetylcholinesterase, a serine hydrolase involved in neurotransmission at cholinergic synapses and neuromuscular junctions.

References

Intorre, L, et al. "Safety of azamethiphos in eel, seabass and trout." Pharmacological Research the Official Journal of the Italian Pharmacological Society 49.2(2004):171. Kaur, K, et al. "Mechanism behind Resistance against the Organophosphate Azamethiphos in Salmon Lice (Lepeophtheirus salmonis). " Plos One 10.4(2015):e0124220.

Chemical Properties

white to light yellow crystal powde

Uses

Azamethiphos is used to control flies and other insect pests in animal houses and also public hygiene and health pests such as mosquitoes and cockroaches. It has recently been used to control sea lice in salmon.

Uses

Synergistic insecticidal and acaricidal organophosphorus compound

Definition

ChEBI: Azamethiphos is an organic thiophosphate, an organothiophosphate insecticide, an organochlorine insecticide and an organochlorine acaricide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an agrochemical. It is functionally related to an oxazolo[4,5-b]pyridin-2(3H)-one.

Safety Profile

Moderately toxic by ingestion andskin contact. When heated to decomposition it emits toxicvapors of NOx, SOx, POx, and Cl- .

Metabolic pathway

Azamethiphos is metabolised in mammals via hydrolysis, followed by opening of the oxazolinone ring and conjugation of the resultant aminopyridinol as the glucuronide and sulfate ester.

Metabolism

Azamethiphos is metabolized via the cleavage of phosphorothiolate C?S bond, followed by N-demethylation and opening of the oxazolinone ring and conjugation of the resultant aminochloropyridinol as the glucuronide and sulfate ester.

Degradation

Azamethiphos is unstable in alkalis and acids. The DT50 values at pH 5,7 and 9 were 800,260 and 4.3 hours, respectively (PM).

Toxicity evaluation

Acute oral LD50 for rats is 1180 mg/kg. Inhalation LC50 (4 h) for rats is >560 mg/m3 air. ADI is 0.025 mg/kg.

Azamethiphos Preparation Products And Raw materials

Global( 289)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weibang Biotechnology Co., Ltd
+8615531157085 abby@weibangbio.com China 8812 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12840 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5893 58
Hebei Mojin Biotechnology Co.,Ltd
+86-15028179902 angelia@hbmojin.com China 1177 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106 sales@frappschem.com China 880 50
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682 bruce@xrdchem.cn CHINA 566 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763 info@tnjchem.com China 2986 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58

View Lastest Price from Azamethiphos manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Azamethiphos pictures 2024-11-19 Azamethiphos
35575-96-3
US $39.00 / mg 97.99% 10g TargetMol Chemicals Inc.
Azamethiphos pictures 2024-10-24 Azamethiphos
35575-96-3
US $1.00 / KG 1KG 99% 10 mt Hebei Weibang Biotechnology Co., Ltd
Azamethiphos pictures 2024-10-11 Azamethiphos
35575-96-3
US $10.00 / KG 1KG 99.8% 100tons Hebei Chuanghai Biotechnology Co,.LTD
  • Azamethiphos pictures
  • Azamethiphos
    35575-96-3
  • US $39.00 / mg
  • 97.99%
  • TargetMol Chemicals Inc.
  • Azamethiphos pictures
  • Azamethiphos
    35575-96-3
  • US $1.00 / KG
  • 99%
  • Hebei Weibang Biotechnology Co., Ltd
  • Azamethiphos pictures
  • Azamethiphos
    35575-96-3
  • US $10.00 / KG
  • 99.8%
  • Hebei Chuanghai Biotechnology Co,.LTD

Azamethiphos Spectrum

s-(6-chlorooxazolo(4,5-b)pyridin-2(3h)-on-3-ylmethyl)o,o-dimethylphosphorot snip AZAMETHIPHOS ALFACRON ALFACRON(R) ALIFICRON(R) Oxazolo(4,5-b)pyridine, phosphorothioic acid deriv. S-(6-chloro-oxazolo[4,5-b]pyridin-2(3H)-on-3-ylmethyl) O,O-dimethyl phosphorothioate Azamethiphos 0 Azamethiphos solution S-((6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl) O,O-dimethyl phosphorothioate S-6-CHLORO-2,3-DIHYDRO-2-OXO-1,3-OXAZOLO[4.5-B]PYRIDIN-3-YLMETHYL-O,O-DIMETHYLPHOSPHOROTHIOATE S-6-CHLORO-2,3-DIHYDRO-2-OXO-OXAZOLO-[4,5-B]PYRIDIN-3-YLMETHYL O,O-DIMETHYL S-6-CHLORO-2,3-DIHYDRO-2-OXO-OXAZOLO[4.5-B]PYRIDIN-3-YLMETHYL-O,O-DIMETHYL PHOSPHOROTHIOATE S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl thiophosphate SNIP(R) SNIP(TM) 5-b)pyridin-2(3h)-on-3-thiophosphorsaeure-o-dimethyl-s-(6-chlor-oxazolo(4 cga18809 AZAMETHIOPHOS PESTANAL AZAMETHIPHOS PESTANAL, 250 MG Azamethiphos-Pesticides S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-Dimethyl Ester Phosphorothioic Acid Salmosan azamethiphos (bsi,iso) S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate SNIP(TM)(100UG/MLINMETHYLENECHLORIDE) O,O-DIMETHYL-S-(6-CHLORO-OXAZOLO(4,5-B)-PYRIDIN-2(3H)-ONE-3-YL-METHYL)-THIOPHOSPHATE S-[6-chloro-oxazolo(4,5-b)pyridin-2(3H)-on-yl-methyl]-O,O-dimethyl-phospophorothioate S-[(6-Chloro-2-oxooxazolo[4,5-β]pyridin-3(2H)-yl)methyl] O,O-Dimethyl Ester Phosphorothioic Acid 6-Chloro-3-(dimethoxyphosphorylsulfanylmethyl)-[1,3]oxazolo[4,5-b]pyridin-2-one Phosphorothioic acid, S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl ester Alfracron GS 40616 O,O-dimethyl-S-[6-chloro-2-oxooxazolo [4,5-b] pyridin-3 (2H)-yl] methyl phosphorothionate Thiophosphoric acid S-(6-chloro-2-oxo-2,3-dihydrooxazolo[4,5-b]pyridin-3-ylmethyl)O,O-dimethyl ester Thiophosphoric acid S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl]O,O-dimethyl ester Azamethiphos 100ug/ml in Methylene chloride 5ml [35575-96-3] Azamethiphos (100ug/ml in Methylene chloride) ciba-geigy18809 o,o-dimethylester phosphorothioicacid,s-((6-chloro-2-oxooxazolo(4,5-b)pyridin-3(2h)-yl)methyl) s-((6-chloro-2-oxooxazolo(4,5-b)pyridin-3(2h)-yl)methyl)o,o-dimethylphosphor Azamethiphos Solution, 100ppm 5-chloro-3-[(dimethoxyphosphorylthio)methyl]-1,3-benzoxazol-2-one AZAMETHYPHOS PHOSPHOROTHIOATE Hot sell Azamethiphos Standard Azamethiphos@1000 μg/mL in Methanol Azamethiphos @100 μg/mL in MeOH Azamethiphos Solution in Acetone, 100μg/mL 4'-Benzophenonetetracarboxylic dianhydride azametifos PHOSPHOROTHIOATE Azametiphos AZAMETHIFOS Azamethiophos Azamethiphos CAS 35575-96-3