4-Chloro-2-methylphenol
- CAS No.
- 1570-64-5
- Chemical Name:
- 4-Chloro-2-methylphenol
- Synonyms
- 4-CHLORO-O-CRESOL;97-99℃;ai3-24520;4-chloro-o-creso;4-CHLORO-2-CRESOL;p-Chloro-o-cresol;4-chloro-0-cresol;o-Cresol, 4-chloro-;4-Chloro-2-methylphe;Chlorocresol (ortho-)
- CBNumber:
- CB5690334
- Molecular Formula:
- C7H7ClO
- Molecular Weight:
- 142.58
- MDL Number:
- MFCD00002321
- MOL File:
- 1570-64-5.mol
- MSDS File:
- SDS
| Melting point | 43-46 °C(lit.) |
|---|---|
| Boiling point | 220-225 °C(lit.) |
| alpha | 22 º (c=8,6N HCl) |
| Density | 1.20 |
| vapor pressure | 26.66Pa at 19.85℃ |
| refractive index | 1.5449 (estimate) |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 9.87±0.18(Predicted) |
| form | crystals |
| color | white to brown |
| Water Solubility | <0.1 g/100 mL at 15 ºC |
| BRN | 1906684 |
| InChIKey | RHPUJHQBPORFGV-UHFFFAOYSA-N |
| LogP | 3.09 at 20℃ |
| CAS DataBase Reference | 1570-64-5(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | 297V63W9RI |
| NIST Chemistry Reference | Phenol, 4-chloro-2-methyl-(1570-64-5) |
| EPA Substance Registry System | 4-Chloro-2-methylphenol (1570-64-5) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H331-H400 | |||||||||
| Precautionary statements | P260-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | T,C,N,Xn | |||||||||
| Risk Statements | 23-35-50-38-21/22 | |||||||||
| Safety Statements | 26-36/37/39-45-61-28 | |||||||||
| RIDADR | UN 3437 6.1/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | GO7120000 | |||||||||
| Hazard Note | Toxic/Corrosive | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29081990 | |||||||||
| Hazardous Substances Data | 1570-64-5(Hazardous Substances Data) | |||||||||
| Toxicity | mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03270, | |||||||||
| NFPA 704 |
|
4-Chloro-2-methylphenol price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C55208 | 4-Chloro-2-methylphenol 97% | 1570-64-5 | 10g | $105 | 2024-03-01 | Buy |
| Sigma-Aldrich | 35833 | 4-Chloro-2-methylphenol PESTANAL?, analytical standard | 1570-64-5 | 100mg | $124 | 2024-03-01 | Buy |
| TCI Chemical | C0152 | 4-Chloro-o-cresol >90.0%(GC) | 1570-64-5 | 25g | $49 | 2024-03-01 | Buy |
| TCI Chemical | C0152 | 4-Chloro-o-cresol >90.0%(GC) | 1570-64-5 | 500g | $191 | 2024-03-01 | Buy |
| Alfa Aesar | L04164 | 4-Chloro-2-methylphenol, 97% | 1570-64-5 | 5g | $44.65 | 2024-03-01 | Buy |
4-Chloro-2-methylphenol Chemical Properties,Uses,Production
Chemical Properties
Off-white to slightly brownish crystalline solid
Uses
4-Chloro-2-methylphenol is a transformation/degredation product of herbicides found in the environment through landfills and runoff.
Definition
ChEBI: 4-chloro-2-methylphenol is a member of the class of phenols that is o-cresol in which the hydrogen para to the hydroxy group is replaced by a chlorine. It is a member of phenols and a member of monochlorobenzenes. It is functionally related to an o-cresol.
Application
4-Chloro-2-methylphenol is an important pharmaceutical intermediate ingredient used in the manufacture of herbicides (Mecoprop, MCPA, and MCPB), as an additive tracer for resist plasma etching. It is used as a closed system intermediate in the production of phenoxy herbicides. It is also used as a disinfectant or bactericide.
Synthesis Reference(s)
Tetrahedron Letters, 30, p. 5215, 1989 DOI: 10.1016/S0040-4039(01)93745-1
General Description
Dark red flakes with waxy texture. Insoluble in water.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
4-Chloro-2-methylphenol can react vigorously with concentrated sodium hydroxide solutions. Also reacts with other bases, acid chlorides, acid anhydrides, and oxidizing agents. Corrodes steel, brass, copper and copper alloys [NTP, 1992)]. A large quantity left in contact with concentrated sodium hydroxide solution for 3 days reacted violently, attaining red heat and evolving fumes that ignited explosively. The heat of reaction dissipated poorly because of the high viscosity of the mixture [Quart. Safety Summ., 1957, 28, 39].
Fire Hazard
4-Chloro-2-methylphenol is probably combustible.
Flammability and Explosibility
Non flammable
Purification Methods
Purify the phenol by crystallisation from pet ether (m 51o) and by zone melting. [Beilstein 6 H 359, 6 I 174, 6 II 332, 6 III 1264, 6 IV 1987.]
4-Chloro-2-methylphenol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang Kinso Technology Co., LTD. | +8619857958369 | sales@kinsopharma.com | China | 54 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18949 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29871 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49476 | 58 |
View Lastest Price from 4-Chloro-2-methylphenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-12 | 4-Chloro-2-methylphenol
1570-64-5
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-07-12 | 4-Chloro-2-methylphenol
1570-64-5
|
US $0.00-0.00 / KG | 1KG | 99% | 10000KG | Zhejiang Kinso Technology Co., LTD. | |
 |
2021-07-13 | 4-Chloro-2-methylphenol
1570-64-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 4-Chloro-2-methylphenol
1570-64-5
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 4-Chloro-2-methylphenol
1570-64-5
- US $0.00-0.00 / KG
- 99%
- Zhejiang Kinso Technology Co., LTD.
-
- 4-Chloro-2-methylphenol
1570-64-5
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd