4-Fluorobenzylamine
- CAS No.
- 140-75-0
- Chemical Name:
- 4-Fluorobenzylamine
- Synonyms
- (4-Fluorophenyl)methanamine;P-FLUOROBENZYLAMINE;Benzylamine, p-fluoro-;NSC 158269;AURORA KA-7685;P-flubenzylamine;AKOS BBS-00003618;4-FLUOROBENZYLAMINE;RARECHEM AL BW 0026;4-fluro benzylamine
- CBNumber:
- CB5716902
- Molecular Formula:
- C7H8FN
- Molecular Weight:
- 125.14
- MDL Number:
- MFCD00008120
- MOL File:
- 140-75-0.mol
- MSDS File:
- SDS
Melting point | 183 °C |
---|---|
Boiling point | 183 °C (lit.) |
Density | 1.095 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | 152 °F |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
form | Liquid |
pka | 9.01±0.10(Predicted) |
color | Clear colorless to light yellow |
Specific Gravity | 1.101.095 |
Water Solubility | Soluble in water. |
Sensitive | Air Sensitive |
BRN | 636501 |
InChIKey | IIFVWLUQBAIPMJ-UHFFFAOYSA-N |
CAS DataBase Reference | 140-75-0(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenemethanamine, 4-fluoro-(140-75-0) |
EPA Substance Registry System | Benzenemethanamine, 4-fluoro- (140-75-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H290-H314 | |||||||||
Precautionary statements | P234-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
Hazard Codes | C,Xi | |||||||||
Risk Statements | 34-20/21/22 | |||||||||
Safety Statements | 26-27-36/37/39-45-36/39 | |||||||||
RIDADR | UN 2735 8/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-34 | |||||||||
Hazard Note | Irritant | |||||||||
TSCA | Yes | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29214980 | |||||||||
NFPA 704 |
|
4-Fluorobenzylamine price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 162493 | 4-Fluorobenzylamine 97% | 140-75-0 | 5g | $36.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 162493 | 4-Fluorobenzylamine 97% | 140-75-0 | 25g | $70 | 2024-03-01 | Buy |
TCI Chemical | F0252 | 4-Fluorobenzylamine >98.0%(GC) | 140-75-0 | 5g | $38 | 2024-03-01 | Buy |
TCI Chemical | F0252 | 4-Fluorobenzylamine >98.0%(GC) | 140-75-0 | 25g | $56 | 2024-03-01 | Buy |
Alfa Aesar | A15486 | 4-Fluorobenzylamine, 98+% | 140-75-0 | 10g | $31.65 | 2024-03-01 | Buy |
4-Fluorobenzylamine Chemical Properties,Uses,Production
Chemical Properties
Colorless to light yellow liquid.
Uses
4-Fluorobenzylamine is used as a potassium channel blocking agent. It is used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands. It reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate2. It is an important building block for the synthesis of 18F-labeled compounds.
General Description
[18F]4-fluorobenzylamine reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate. It is an important building block for the synthesis of 18F-labeled compounds.
Synthesis
In a 100ml reaction flask, add 25.5g (0.1mol) of N-(4-fluorobenzyl)phthalimide and 25ml of absolute ethanol, then add 6.3g (0.1mol) of 80% hydrazine hydrate solution, and heat Reflux 0.5g. Excessive hydrochloric acid was added to decompose the precipitated white precipitate, after cooling, an appropriate amount of water was added to stir, and suction filtered. The filtrate was neutralized with NaOH solution, extracted with ether, and the ether extract was dried, evaporated to remove ether, distilled under reduced pressure, and collected fractions at 44-46°C (67kPa) to obtain 7.1 g of 4-fluorobenzylamine, with a yield of 56.5%.
4-Fluorobenzylamine Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9740 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5895 | 58 |
Hebei Mojin Biotechnology Co.,Ltd | +86-15028179902 | angelia@hbmojin.com | China | 1143 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 811 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21663 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
View Lastest Price from 4-Fluorobenzylamine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-29 | 4-Fluorobenzylamine
140-75-0
|
US $20.00-20.00 / kg | 1kg | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-09-09 | 4-Fluorobenzylamine
140-75-0
|
US $0.00 / kg | 1kg | 99% | 50000KG/month | Hebei Mojin Biotechnology Co.,Ltd | ||
2024-09-02 | 4-Fluorobenzylamine
140-75-0
|
US $10.00-150.00 / kg | 1kg | NLT98% | 2 ton per month | Anhui Dexinjia Biopharm Co., Ltd |
- 4-Fluorobenzylamine
140-75-0
- US $20.00-20.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- 4-Fluorobenzylamine
140-75-0
- US $0.00 / kg
- 99%
- Hebei Mojin Biotechnology Co.,Ltd
- 4-Fluorobenzylamine
140-75-0
- US $10.00-150.00 / kg
- NLT98%
- Anhui Dexinjia Biopharm Co., Ltd