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MSA-2

CAS No.
129425-81-6
Chemical Name:
MSA-2
Synonyms
MSA-2;4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobut;5,6-Dimethoxy-γ-oxobenzo[b]thiophene-2-butanoic acid;Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-γ-oxo-;4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid;4- (5,6-Dimethoxybenzo [b] thiophen-2-yl) -4-oxobutyric acid;interferon-β,Inhibitor,TMEM173,ERIS,MPYS,immunity,secretion,tumor,Stimulator of Interferon Genes,MSA 2,MC38,STING,MSA2,TNF-α,MITA,MSA-2,inhibit
CBNumber:
CB57244028
Molecular Formula:
C14H14O5S
Molecular Weight:
294.32
MDL Number:
MFCD32640674
MOL File:
129425-81-6.mol
Last updated:2024-07-02 08:55:11

MSA-2 Properties

Boiling point 509.3±50.0 °C(Predicted)
Density 1.336±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility DMSO: 125 mg/mL (424.71 mM)
form A crystalline solid
pka 4.35±0.17(Predicted)
color Light yellow to brown

SAFETY

Risk and Safety Statements

MSA-2 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 7353 MSA2 ≥98%(HPLC) 129425-81-6 50 $569 2021-12-16 Buy
ChemScene CS-0135308 MSA-2 98.79% 129425-81-6 10mg $580 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-0164-M005 MSA-2 ≥98% 129425-81-6 5mg $80 2021-12-16 Buy
ChemScene CS-0135308 MSA-2 98.79% 129425-81-6 5mg $350 2021-12-16 Buy
ChemScene CS-0135308 MSA-2 98.79% 129425-81-6 25mg $1100 2021-12-16 Buy
Product number Packaging Price Buy
7353 50 $569 Buy
CS-0135308 10mg $580 Buy
AG-CR1-0164-M005 5mg $80 Buy
CS-0135308 5mg $350 Buy
CS-0135308 25mg $1100 Buy

MSA-2 Chemical Properties,Uses,Production

Description

MSA-2 was identified in a phenotypic screen for a chemical inducer of interferon beta secretion. In cell-free assays, MSA-2 binds to human and mouse STING. In tumor-bearing mice, MSA-2 induced elevated interferon-beta in plasma and tumors through two routes of administration.

Uses

MSA-2 is an oral non-nucleotide STING agonist with EC50 of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively.

storage

Store at -20°C

MSA-2 Preparation Products And Raw materials

Raw materials

Preparation Products

MSA-2 Suppliers

Global( 69)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32760 60
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10522 58
Henan Alfa Chemical Co., Ltd
+8618339805032 alfa4@alfachem.cn China 13141 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139 orders@jknbiochem.com China 4692 58

MSA-2 Spectrum

4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-γ-oxo- MSA-2 5,6-Dimethoxy-γ-oxobenzo[b]thiophene-2-butanoic acid interferon-β,Inhibitor,TMEM173,ERIS,MPYS,immunity,secretion,tumor,Stimulator of Interferon Genes,MSA 2,MC38,STING,MSA2,TNF-α,MITA,MSA-2,inhibit 4- (5,6-Dimethoxybenzo [b] thiophen-2-yl) -4-oxobutyric acid 4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobut 129425-81-6 294425-81-6