ChemicalBook >> CAS DataBase List >>Phthalazine

Phthalazine

CAS No.
253-52-1
Chemical Name:
Phthalazine
Synonyms
PHZ;PHTHALAZINE;β-Phenodiazine;Phthalazine>Phthalazine~99%;Phthalazine,98%;2,3-Benzodiazin;2,3-BENZODIAZINE;beta-Phenodiazine;BENZO[D]PYRIDAZINE
CBNumber:
CB5734171
Molecular Formula:
C8H6N2
Molecular Weight:
130.15
MDL Number:
MFCD00006908
MOL File:
253-52-1.mol
MSDS File:
SDS
Last updated:2024-05-27 11:36:15

Phthalazine Properties

Melting point 89-92 °C(lit.)
Boiling point 189 °C29 mm Hg(lit.)
Density 1.1509 (rough estimate)
refractive index 1.6231 (estimate)
Flash point 178-180°C/15mm
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline Powder
pka 3.47(at 20℃)
color Slightly brown to beige
Water Solubility Soluble in water, methanol, chloroform.
Merck 14,7370
BRN 109240
CAS DataBase Reference 253-52-1(CAS DataBase Reference)
FDA UNII 91Y28DM24N
NIST Chemistry Reference Phthalazine(253-52-1)
EPA Substance Registry System Phthalazine (253-52-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H341-H412
Precautionary statements  P202-P273-P280-P308+P313-P405-P501
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-68
Safety Statements  24/25-37/39-36-26-36/37/39
WGK Germany  3
TSCA  Yes
HS Code  29339900
NFPA 704
1
2 0

Phthalazine price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P38706 Phthalazine 98% 253-52-1 1g $46.3 2024-03-01 Buy
Sigma-Aldrich 1535959 Phthalazine United States Pharmacopeia (USP) Reference Standard 253-52-1 20mg $1150 2024-03-01 Buy
TCI Chemical P0694 Phthalazine >98.0%(GC)(T) 253-52-1 5g $33 2024-03-01 Buy
TCI Chemical P0694 Phthalazine >98.0%(GC)(T) 253-52-1 25g $101 2024-03-01 Buy
Alfa Aesar A12270 Phthalazine, 98% 253-52-1 5g $65.65 2024-03-01 Buy
Product number Packaging Price Buy
P38706 1g $46.3 Buy
1535959 20mg $1150 Buy
P0694 5g $33 Buy
P0694 25g $101 Buy
A12270 5g $65.65 Buy

Phthalazine Chemical Properties,Uses,Production

Chemical Properties

SLIGHTLY BROWN TO BEIGE CRYSTALLINE POWDER

Uses

Phthalazine is a heterocyclic organic compound isomeric with quinoxaline, cinnoline and quinazoline. Aminophthalazine compounds serve as effective phosphodiesterase (PDE) inhibitors.

Uses

Phthalazine derivatives including copper and platinum complexes were induce the apoptosis in breast cancer cell lines and renal hyperemia.

Definition

ChEBI: Phthalazine is an azaarene that is the 2,3-diaza analogue of naphthalene. The parent of the class of phthalazines. It is a mancude organic heterobicyclic parent, a member of phthalazines, an azaarene and an ortho-fused heteroarene.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 2, p. 206, 1965 DOI: 10.1002/jhet.5570020219

Purification Methods

Phthalazine crystallises from diethyl ether or *benzene, and sublimes under a vacuum. The hydrochloride forms needles from EtOH with m 235-236o(dec) and the picrate has m 208-210o. [Armarego J Appl Chem 11 70 1961, Beilstein 23 H 174, 23 III/IV 1233.]

Phthalazine Preparation Products And Raw materials

Global( 229)Suppliers
Supplier Tel Email Country ProdList Advantage
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
+8618291886785 olivia.wang@pushanshiye.com China 164 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34553 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58

View Lastest Price from Phthalazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Phthalazine pictures 2024-09-09 Phthalazine
253-52-1
US $0.00 / kg 1kg 98% 5 MTs PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Phthalazine pictures 2019-07-06 Phthalazine
253-52-1
US $1.00 / KG 1KG 99% Customized Career Henan Chemical Co
  • Phthalazine pictures
  • Phthalazine
    253-52-1
  • US $0.00 / kg
  • 98%
  • PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
  • Phthalazine pictures
  • Phthalazine
    253-52-1
  • US $1.00 / KG
  • 99%
  • Career Henan Chemical Co
2,3-Diazanaphthalene beta-Phenodiazine β-Phenodiazine 4,5-BENZOPYRIDAZINE 2,3-BENZODIAZINE BENZO[D]PYRIDAZINE PHTHALAZINE PHZ Phthalazine~99% 4,5-Benzo-1,2-diazine Phthalazine,98% 2,3-Benzodiazine 4,5-Benzopyridazine Phthalazine, 2,3-Benzodiazine Phthalazine, 98% 10GR Hydralazine Hydrochloride Impurity Ⅰ:Phthalazine Phthalazine Phthalazine Phthalazine> 2,3-Benzodiazin Hydralazine Hydrochloride Impurity Ⅰ:Phthalazine Phthalazine (6CI, 7CI, 8CI, 9CI, ACI) Hydralizine EP impurity-D Phthalazine, ≥ 98.0% *Furosemide Impurity 32 253-52-1 Pyridazines Heterocyclic Building Blocks Building Blocks Building Blocks Heterocyclic Building Blocks Pyridazines