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Boc-C1-PEG3-C4-OBn

CAS No.
2381196-81-0
Chemical Name:
Boc-C1-PEG3-C4-OBn
Synonyms
Boc-C1-PEG3-C4-OBn;tert-butyl 2-[2-[2-(6-benzyloxyhexoxy)ethoxy]ethoxy]acetate;3,6,9,16-Tetraoxaheptadecanoic acid, 17-phenyl-, 1,1-dimethylethyl ester
CBNumber:
CB58054684
Molecular Formula:
C23H38O6
Molecular Weight:
410.54
MDL Number:
MFCD32689583
MOL File:
2381196-81-0.mol
Last updated:2024-07-02 08:55:11

Boc-C1-PEG3-C4-OBn Properties

Boiling point 486.9±40.0 °C(Predicted)
Density 1.029±0.06 g/cm3(Predicted)
solubility Soluble in DMSO
form Liquid
color Light yellow to yellow

Boc-C1-PEG3-C4-OBn Chemical Properties,Uses,Production

Biological Activity

Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PROTAC linker, which refers to the PEG composition. Boc-C1-PEG3-C4-OBn can be used in the synthesis of a series of PROTACs, such as PROTAC SGK3 degrader-1. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTACDegrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

Boc-C1-PEG3-C4-OBn Preparation Products And Raw materials

Raw materials

Preparation Products

Boc-C1-PEG3-C4-OBn Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49323 58
Shanghai Haohong Pharmaceutical Co., Ltd. 4008210725 4008210725 malulu@leyan.com China 54986 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50471 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28070 58
Boc-C1-PEG3-C4-OBn tert-butyl 2-[2-[2-(6-benzyloxyhexoxy)ethoxy]ethoxy]acetate 3,6,9,16-Tetraoxaheptadecanoic acid, 17-phenyl-, 1,1-dimethylethyl ester 2381196-81-0