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ChemicalBook >> CAS DataBase List >>1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)-

1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)-

1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- Structure
1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- structure
CAS No.
1620056-83-8
Chemical Name:
1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)-
Synonyms
Apremilast Impurity 123;2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl)-7,8-diazatricyclo[4.3.0.02,?]nona-1(6),8-dien-7-yl]acetic acid;(3bS,4aR)-5,5-Difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid;1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)-;2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetic acid;2 - ((3Bs, 4ar) - 5,5-difluoro-3 - (trifluoromethyl) - 3b, 4,4a, 5-tetrahydro-1h-cyclopropane [3,4] cyclopentyl [1,2-c] pyrazole-1-yl) acetic acid
CBNumber:
CB58106112
Molecular Formula:
C10H7F5N2O2
Molecular Weight:
282.17
MDL Number:
MOL File:
1620056-83-8.mol
Last updated:2024-07-16 13:24:06
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1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- Properties

Boiling point 325.8±42.0 °C(Predicted)
Density 1.96±0.1 g/cm3(Predicted)
pka 3.49±0.10(Predicted)

1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- Chemical Properties,Uses,Production

Uses

1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- is a pharmaceutical intermediate component, which can be used as a preparation of long-acting HIV capsid inhibitors.

1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- synthesis

58001-78-8
1620056-83-8
Synthesis of 1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- from (1R,5S)-bicyclo[3.1.0]hexan-2-one

1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- Preparation Products And Raw materials

Raw materials

(1R,5S)-bicyclo[3.1.0]hexan-2-one

Preparation Products

1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
ChemExpress 		+86-021-58950125 +86-021-58950125; info@chemexpress.com China 780 58
Unibest Industrial Co.,Ltd. 		+86-8657427855777 +86-18758850676 info@unibestcn.com China 229 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Aceschem Inc. 		+1-817863-6948 +1-（817）863-6948 sales@aceschem.com United States 19632 58
Porton Pharma Solutions Ltd. China 56 58
Suzhou Jianghua Biotechnology Co., Ltd 0512-0000000 15151741136 3045580592@qq.com China 32 58
WuYan Pharmaceutical Technology (Shanghai) Co., Ltd. 021-61001086 13671938079 sales@wuyanpharm.com China 105 55
Nantong Nuotai Biomedical Technology Co., Ltd. 0513-82206272 17706270880 479758216@qq.com China 170 58
Shanghai Boc Chemical Co.,Ltd 021-34975603-808 18721111801 sales@bocpharma.com China 998 64
Supplier Advantage
Jinan Carbotang Biotech Co.,Ltd. 		58
ChemExpress 		58
Unibest Industrial Co.,Ltd. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Aceschem Inc. 		58
Porton Pharma Solutions Ltd. 58
Suzhou Jianghua Biotechnology Co., Ltd 58
WuYan Pharmaceutical Technology (Shanghai) Co., Ltd. 55
Nantong Nuotai Biomedical Technology Co., Ltd. 58
Shanghai Boc Chemical Co.,Ltd 64
1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid, 5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)- 2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetic acid 2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl)-7,8-diazatricyclo[4.3.0.02,?]nona-1(6),8-dien-7-yl]acetic acid 2 - ((3Bs, 4ar) - 5,5-difluoro-3 - (trifluoromethyl) - 3b, 4,4a, 5-tetrahydro-1h-cyclopropane [3,4] cyclopentyl [1,2-c] pyrazole-1-yl) acetic acid (3bS,4aR)-5,5-Difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-acetic acid Apremilast Impurity 123 1620056-83-8 3