(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol

(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol structure

CAS No.: 216481-88-8

Chemical Name:: (1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol

Synonyms: (1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol;2-Cyclopentene-1-methanol, 4-(2-amino-6-chloro-9H-purin-9-yl)-, (1R,4S)-

CBNumber:: CB58286731

Molecular Formula:: C11H12ClN5O

Molecular Weight:: 265.7

MDL Number:

MOL File:: 216481-88-8.mol

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(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Properties

Boiling point	572.0±60.0 °C(Predicted)
Density	1.74±0.1 g/cm3(Predicted)
pka	14.86±0.10(Predicted)

(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A595930	(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol	216481-88-8	10mg	$365	2021-12-16	Buy

Product number	Packaging	Price	Buy
A595930	10mg	$365	Buy

(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Chemical Properties,Uses,Production

Uses

(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Preparation Products And Raw materials

Raw materials

Preparation Products

(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58
BOC Sciences	16314854226	inquiry@bocsci.com	United States	9713	58

Supplier	Advantage
BOC Sciences	58
BOC Sciences	58

(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol 2-Cyclopentene-1-methanol, 4-(2-amino-6-chloro-9H-purin-9-yl)-, (1R,4S)- 216481-88-8