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GMB-475

GMB-475 Structure
GMB-475 structure
CAS No.
2490599-18-1
Chemical Name:
GMB-475
Synonyms
GMB-475;Bcr-Abl,GMB-475,PROTACs,GMB 475,Apoptosis,Inhibitor,inhibit,GMB475;(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CBNumber:
CB58379743
Molecular Formula:
C43H46F3N7O7S
Molecular Weight:
861.94
MDL Number:
MOL File:
2490599-18-1.mol
Last updated:2024-07-02 08:55:12
Request For Quotation

GMB-475 Properties

Boiling point 1029.7±65.0 °C(Predicted)
Density 1.337±0.06 g/cm3(Predicted)
solubility DMSO:145.4(Max Conc. mg/mL);168.69(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);58.01(Max Conc. mM)
form Solid
pka 13.50±0.46(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

GMB-475 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Ambeed A1235114 (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98% 2490599-18-1 1mg $77 2021-12-16 Buy
Ambeed A1235114 (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98% 2490599-18-1 5mg $153 2021-12-16 Buy
Ambeed A1235114 (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98% 2490599-18-1 10mg $238 2021-12-16 Buy
Ambeed A1235114 (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98% 2490599-18-1 25mg $309 2021-12-16 Buy
Ambeed A1235114 (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98% 2490599-18-1 50mg $402 2021-12-16 Buy
Product number Packaging Price Buy
A1235114 1mg $77 Buy
A1235114 5mg $153 Buy
A1235114 10mg $238 Buy
A1235114 25mg $309 Buy
A1235114 50mg $402 Buy

GMB-475 Chemical Properties,Uses,Production

Description

GMB-475 acts as a degrader of BCR-ABL 1 tyrosine kinase and as a recruiter of the E3 ligase Von Hippel Lindau (VHL) resulting in ubiquitination and subsequent degradation of oncogenic fusion proteins.

storage

Store at -20°C

GMB-475 Preparation Products And Raw materials

Raw materials

Preparation Products

GMB-475 Suppliers

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Chuchang Biotech Co., Ltd. 		+86-18727130788 +86-18727130788 info@chuchangbiotech.com China 109 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 4692 58
Shanghai YuanQi Biotechnology Co., Ltd. +86-2332782371 +86-18120098618 sales@adobechem.com China 1250 50
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613 sales@chemrenpharm.com China 3574 58
Shanghaizehan biopharma technology co., Ltd. 021-61350663 13052117465 sales@zehanbiopharma.com China 1000 55
Supplier Advantage
Hubei Chuchang Biotech Co., Ltd. 		58
InvivoChem 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Shanghai YuanQi Biotechnology Co., Ltd. 50
Changzhou Chenhong Biotechnology Co., Ltd. 58
Shanghaizehan biopharma technology co., Ltd. 55

View Lastest Price from GMB-475 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GMB-475 pictures 2024-07-22 GMB-475
2490599-18-1
 US $0.00-0.00 / mg 1mg 98% 100G Hubei Chuchang Biotech Co., Ltd.
  • GMB-475 pictures
  • GMB-475
    2490599-18-1
  • US $0.00-0.00 / mg
  • 98%
  • Hubei Chuchang Biotech Co., Ltd.

GMB-475 Spectrum

GMB-475(2490599-18-1)1HNMR
(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide GMB-475 Bcr-Abl,GMB-475,PROTACs,GMB 475,Apoptosis,Inhibitor,inhibit,GMB475 2490599-18-1 C43H46F3N7O7S