Tributyrin
- CAS No.
- 60-01-5
- Chemical Name:
- Tributyrin
- Synonyms
- GLYCEROL TRIBUTYRATE;GLYCERYL TRIBUTYRATE;C4:0;FEMA 2223;Glycerol tributanoate;BUTYRIN;C15H26O6;TRI-N-BUTYRIN;Butanoic acid, 1,2,3-propanetriyl ester;Kodaflex
- CBNumber:
- CB5853942
- Molecular Formula:
- C15H26O6
- Molecular Weight:
- 302.36
- MDL Number:
- MFCD00009392
- MOL File:
- 60-01-5.mol
- MSDS File:
- SDS
| Melting point | -75 °C |
|---|---|
| Boiling point | 305 °C |
| Density | 1.0335 |
| FEMA | 2223 | (TRI-)BUTYRIN |
| refractive index |
n |
| Flash point | 345 °F |
| storage temp. | Store at RT. |
| solubility | H2O: insoluble |
| form | Liquid |
| color | Clear colorless to yellow |
| Odor | at 100.00 %. cheese waxy creamy fatty |
| Odor Type | cheesy |
| biological source | synthetic |
| Water Solubility | Not miscible in water. |
| Merck | 14,9620 |
| JECFA Number | 922 |
| BRN | 1714746 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | UYXTWWCETRIEDR-UHFFFAOYSA-N |
| LogP | 2.95 |
| FDA 21 CFR | 184.1903 |
| Substances Added to Food (formerly EAFUS) | GLYCEROL TRIBUTYRATE |
| CAS DataBase Reference | 60-01-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | S05LZ624MF |
| NCI Dictionary of Cancer Terms | tributyrin |
| NCI Drug Dictionary | tributyrin |
| EPA Substance Registry System | Tributyrin (60-01-5) |
| UNSPSC Code | 85151701 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P280-P361+P364-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P405 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | ET7350000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29171900 | |||||||||
| Hazardous Substances Data | 60-01-5(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
Tributyrin price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 91010 | Glyceryl tributyrate puriss., ≥98.5% (GC) | 60-01-5 | 25ml | $86.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 73105 | Glyceryl tributyrate analytical standard | 60-01-5 | 1ml | $82.8 | 2024-03-01 | Buy |
| TCI Chemical | T0364 | Tributyrin >98.0%(GC) | 60-01-5 | 25mL | $30 | 2024-03-01 | Buy |
| TCI Chemical | T0364 | Tributyrin >98.0%(GC) | 60-01-5 | 500mL | $216 | 2024-03-01 | Buy |
| Alfa Aesar | A11830 | Glycerol tributyrate, 98% | 60-01-5 | 50g | $31.6 | 2024-03-01 | Buy |
Tributyrin Chemical Properties,Uses,Production
Description
Tributyrin (C15H26O6), also known as butyrin or glyceryl tributyrate, is the triester of glycerin and butyric acid. It is prepared by esterifcation of glycerin with excess butyric acid. Glycerol tributyrate has a characteristic odor and a bitter taste.
Chemical Properties
Tributyrin is a colorless, oily liquid with a bitter taste. It is soluble in alcohol and ether and fairly insoluble in water.
Uses
Tributyrin is a flavoring agent that is the triester of glycerin and butyric acid. it is prepared by esterification of glycerin with excess butyric acid. it is used in the following foods: baked goods; alcoholic beverages; nonalcoholic beverages; fats and oils; frozen dairy des- serts and mixes; gelatins, puddings and fillings; and soft candy. it is also termed butyrin and glyceryl tributyrate.
Definition
ChEBI: A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by butyric acid.
Production Methods
Tributyrin is manufactured via esterification of glycerol with butyric acid.
Preparation
Prepared by esterifcation of glycerol with excess butyric acid.
Taste threshold values
Taste characteristics at 30 ppm: bitter, waxy, fatty, cheese and butter nuances.
General Description
Tributyrin is a short-chain triacylglycerol that mainly occurs in butter. It shows potent anti-cancer property.
Safety Profile
Poison by intravenous route. Low toxicity by ingestion. Questionable carcinogen with experimental tumorigenic data. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes.
Carcinogenicity
Administration of sodium butyrate in drinking water potentiates 1,2-dimethylhydrazine- induced colon cancer in rats . In mice, dietary administration of 5% tributyrin for 48 weeks did not lead to an increase in colonic tumor incidence or focal areas of dysplasia as compared to controls . Therefore, it has been suggested that the agent responsible for enhanced tumorigenesis in the rat study was sodium, rather than butyrate.
Tributyrin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8804 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5855 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5887 | 58 |
| Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 | sales1@hbganmiao.com | China | 227 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| airuikechemical co., ltd. | +86-18353166132 +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 662 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21632 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | FandaChem@Gmail.com | China | 8241 | 55 |
Related Qustion
- Q:What are the Benefits of Tributyrin?
- A:The benefits of Tributyrin are mainly seen in gut health, it can restore the dysbiosis of gut microbiota, increase SCFAs, supp....
- Nov 2，2024
View Lastest Price from Tributyrin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-18 | Tributyrin
60-01-5
|
US $70.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2025-02-18 | Glyceryl tributyrate
60-01-5
|
US $70.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2025-02-18 | Tributyrin
60-01-5
|
US $99.00-35.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- Tributyrin
60-01-5
- US $70.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Glyceryl tributyrate
60-01-5
- US $70.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Tributyrin
60-01-5
- US $99.00-35.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd