ChemicalBook >> CAS DataBase List >>2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1)

2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1)

2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1) structure

CAS No.: 2365306-62-1

Chemical Name:: 2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1)

Synonyms: Umibecestat HCl;2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1)

CBNumber:: CB610452912

Molecular Formula:: C19H16Cl2F7N5O2

Molecular Weight:: 550.26

MDL Number:

MOL File:: 2365306-62-1.mol

Last updated:2023-03-31 09:12:58

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2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1) Chemical Properties,Uses,Production

Description

Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies. CNP520 reduced brain and cerebrospinal fluid (CSF) Aβ in rats and dogs, and Aβ plaque deposition in APP-transgenic mice. CNP520 reduces Aβ load and neuroinflammation in APP‐transgenic mice

2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1) Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chunchuang (Wuhan) Technology Co., Ltd	15342225168	yutianchun2007@126.com	China	10001	58
Wuhan Shanhai Zhihe Biotechnology Co., Ltd.	17771424646	shoubull@126.com	China	965	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19696	58

Supplier	Advantage
Chunchuang (Wuhan) Technology Co., Ltd	58
Wuhan Shanhai Zhihe Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58

2-Pyridinecarboxamide, N-[6-[(3R,6R)-5-amino-3,6-dihydro-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoro-2-pyridinyl]-3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1) Umibecestat HCl 2365306-62-1 C19H16Cl2F7N5O2