ChemicalBook >> CAS DataBase List >>INDEX NAME NOT YET ASSIGNED

INDEX NAME NOT YET ASSIGNED

CAS No.
2699607-86-6
Chemical Name:
INDEX NAME NOT YET ASSIGNED
Synonyms
4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-(2-((2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)amino)acetamido)-1,11-dioxo-1,4S,4aS,5,5aR,6,11,12aS-octahydrotetracene-2-carboxamide
CBNumber:
CB610710726
Molecular Formula:
C29H39N5O8
Molecular Weight:
585.66
MDL Number:
MOL File:
2699607-86-6.mol
Last updated:2024-10-28 23:16:16

INDEX NAME NOT YET ASSIGNED Properties

solubility DMSO: Slightly Soluble; Methanol: Slightly Soluble; Water: Slightly Soluble
form A solid
color Yellow to orange

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
NFPA 704
0
2 0

INDEX NAME NOT YET ASSIGNED price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25414 Tigecycline-d9 ≥99% deuterated forms (d1-d9) 2699607-86-6 500μg $184 2024-03-01 Buy
Cayman Chemical 25414 Tigecycline-d9 ≥99% deuterated forms (d1-d9) 2699607-86-6 1mg $347 2024-03-01 Buy
Product number Packaging Price Buy
25414 500μg $184 Buy
25414 1mg $347 Buy

INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production

Description

Tigecycline-d9 is intended for use as an internal standard for the quantification of tigecycline by GC- or LC-MS. Tigecycline is a broad-spectrum glycylcycline antibiotic that binds to the bacterial 30S ribosome, blocking the entry of transfer RNA, which halts protein synthesis and inhibits bacterial growth.1 It is active against a panel of 1,924 European clinical bacterial isolates including S. aureus, S. epidermidis, S. pneumoniae, E. faecalis, E. faecium, E. coli, K. pneumoniae, P. aeruginosa, and P. mirabilis strains (MICs = <1-32 μg/ml).2 In vivo, tigecycline (6.25 mg/kg twice daily for 5 days) decreases levels of C. difficile cytotoxin activity and spore formation in cecum and colon in a mouse model of C. difficile infection.3 Formulations containing tigecycline have been used in the treatment of a variety of bacterial infections.

References

1. Greer, N.D. Tigecycline (Tygacil): The first in the glycylcycline class of antibiotics Proc. (Bayl. Univ. Med. Cent.) 19(2),155-161(2006).
2. Milatovic, D., Schmitz, F.J., Verhoef, J., et al. Activities of the glycylcycline tigecycline (GAR-936) against 1,924 recent European clinical bacterial isolates Antimicrob. Agents Chemother. 47(1),400-404(2003).
3. Theriot, C.M., Schumacher, C.A., Bassis, C.M., et al. Effects of tigecycline and vancomycin administration on established Clostridium difficile infection Antimicrob. Agents Chemother. 59(3),1596-1604(2015).

INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials

Raw materials

Preparation Products

INDEX NAME NOT YET ASSIGNED Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
Artis Biotech Co. Ltd. 0575-18780151478 18582380095 sales@artisbio.com China 2965 58
PureChemland Co.,Ltd. 19936016343 3848291069@qq.com China 3594 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900 judy.xia@synzest.com China 12582 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12065 58

View Lastest Price from INDEX NAME NOT YET ASSIGNED manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tigecycline-d9 pictures 2024-10-28 Tigecycline-d9
2699607-86-6
US $0.00-0.00 / mg 10g TargetMol Chemicals Inc.
4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-(2-((2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)amino)acetamido)-1,11-dioxo-1,4S,4aS,5,5aR,6,11,12aS-octahydrotetracene-2-carboxamide 2699607-86-6