ChemicalBook >> CAS DataBase List >>2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI)
2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI)
- CAS No.
- 191115-88-5
- Chemical Name:
- 2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI)
- Synonyms
- 2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI)
- CBNumber:
- CB61081088
- Molecular Formula:
- C4H3FN2O2
- Molecular Weight:
- 130.0772232
- MDL Number:
- MFCD28961017
- MOL File:
- 191115-88-5.mol
Last updated:2023-05-04 17:34:35
2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI) Chemical Properties,Uses,Production
Definition
ChEBI: 5-fluorouracil is a nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth. It has a role as a xenobiotic, an environmental contaminant, a radiosensitizing agent, an antineoplastic agent, an immunosuppressive agent and an antimetabolite. It is a nucleobase analogue and an organofluorine compound. It is functionally related to a uracil.
2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI)
191115-88-5
PYRIMIDINE