Polyprenic
- CAS No.
- 81485-25-8
- Chemical Name:
- Polyprenic
- Synonyms
- E-5166;NIK-333;Polyprenic;POLYPRENOICACID;NIK-333;NIK333;NIK 333;Peretinoin, 10 mM in DMSO;4,5-Dehydrogeranylgeranoic acid;4,5-Didehydrogeranylgeranoic acid;3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid;all-trans-3,7,11,15-Tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
- CBNumber:
- CB61179550
- Molecular Formula:
- C20H30O2
- Molecular Weight:
- 302.45
- MDL Number:
- MFCD01742209
- MOL File:
- 81485-25-8.mol
| Boiling point | 460.3±24.0 °C(Predicted) |
|---|---|
| Density | 0.943±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetonitrile (Slightly, Heated), Benzene (Slightly), Chloroform (Slightly) |
| pka | 4.79±0.33(Predicted) |
| form | Solid |
| color | Pale Brown to Orange |
| FDA UNII | 11ALM7A4RV |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
Polyprenic price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P286120 | Peretinoin | 81485-25-8 | 5mg | $215 | 2021-12-16 | Buy |
| ChemScene | CS-5529 | Peretinoin 99.79% | 81485-25-8 | 5mg | $252 | 2021-12-16 | Buy |
| ChemScene | CS-5529 | Peretinoin 99.79% | 81485-25-8 | 10mg | $420 | 2021-12-16 | Buy |
| AK Scientific | 3260BB | Peretinoin | 81485-25-8 | 100mg | $456 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0015454 | PERETINOIN 95.00% | 81485-25-8 | 5MG | $496.36 | 2021-12-16 | Buy |
Polyprenic Chemical Properties,Uses,Production
Uses
Peretinoin is an acyclic retinoid that may have the ability to inhibit hepatic carcinogenesis
Biological Activity
Peretinoin is an orally active synthetic acyclic retinoid (ACR) whose in vivo anti-hepatocellular carcinoma (HCC) efficacy is attributed to its upregulatory activity toward retinoid nuclear receptors (RARbeta & RXRalpha), as well as negative regulation against sphingosine kinase 1 (SPHK1) expression and, thereby, sphingosine metabolic pathway. Peretinoin inhibits the replication of hepatitis B & C viruses in cultures (HBV & HCV EC50 = 9-25 μM) and shows in vivo efficacy in rodent models of hepatocarcinogenesis among rats (10, 40, or 80 mg/kg/day p.o.) and mice (0.03% or 0.06% in diet) subjected to chronic inflammation induction by diethylnitrosamine (DEN).
Polyprenic Preparation Products And Raw materials
Raw materials
Preparation Products
Polyprenic Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8831 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2922 | 55 | |
| Shanghai Fuhe Chemistry Technology Co., Ltd. | 0086-21-67651709 | cfx759@hotmail.com | China | 410 | 57 |
| Suzhou Lakestar Pharmatech Co., Ltd. | 0512-63970158-603 18018108880 | info@lakestarpharma.com | China | 416 | 59 |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
| Raw material medicin reagent co.,Ltd | sales@njromanme.com | China | 4529 | 58 |
View Lastest Price from Polyprenic manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Peretinoin
81485-25-8
|
US $34.00-80.00 / mg | 99.86% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-10-22 | Polyprenic
81485-25-8
|
US $8.00 / KG | 1g | Min98% HPLC/GC | g/kg/ton | Career Henan Chemica Co |
-
- Peretinoin
81485-25-8
- US $34.00-80.00 / mg
- 99.86%
- TargetMol Chemicals Inc.
-
- Polyprenic
81485-25-8
- US $8.00 / KG
- Min98% HPLC/GC
- Career Henan Chemica Co