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4-Chloro-N-methylpicolinamide

4-Chloro-N-methylpicolinamide Structure
4-Chloro-N-methylpicolinamide structure
CAS No.
220000-87-3
Chemical Name:
4-Chloro-N-methylpicolinamide
Synonyms
4-Chloro-N-methylpicolinamide;4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE;4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE;oro-N-methyL;Sorafenib INT3;CAS:220000-87-3;4-Chloropyridine-2;IFLAB-BB F2108-0189;-2-pyridinecarboxamide;Sorafenib impurities13
CBNumber:
CB6134053
Molecular Formula:
C7H7ClN2O
Molecular Weight:
170.6
MDL Number:
MFCD02185921
MOL File:
220000-87-3.mol
MSDS File:
SDS
Last updated:2024-05-14 16:41:43
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4-Chloro-N-methylpicolinamide Properties

Melting point 41-43°C
Boiling point 317.8±27.0 °C(Predicted)
Density 1.264±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
form Solid
pka 13.41±0.46(Predicted)
color Off-White to Light Yellow
CAS DataBase Reference 220000-87-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
HS Code  2933399990
NFPA 704
1
2 0

4-Chloro-N-methylpicolinamide price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2793 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) 220000-87-3 1g $33 2024-03-01 Buy
TCI Chemical C2793 4-Chloro-N-methyl-2-pyridinecarboxamide >98.0%(HPLC)(T) 220000-87-3 5g $132 2024-03-01 Buy
Alfa Aesar H50535 4-Chloro-N-methylpyridine-2-carboxamide, 97% 220000-87-3 250mg $64.65 2024-03-01 Buy
Alfa Aesar H50535 4-Chloro-N-methylpyridine-2-carboxamide, 97% 220000-87-3 1g $216.65 2024-03-01 Buy
TRC C379950 4-Chloro-N-methylpyridine-2-carboxamide(>90%) 220000-87-3 25g $440 2021-12-16 Buy
Product number Packaging Price Buy
C2793 1g $33 Buy
C2793 5g $132 Buy
H50535 250mg $64.65 Buy
H50535 1g $216.65 Buy
C379950 25g $440 Buy

4-Chloro-N-methylpicolinamide Chemical Properties,Uses,Production

Description

4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib.

Chemical Properties

Pale-Yellow Solid

Uses

4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis.

4-Chloro-N-methylpicolinamide synthesis

24484-93-3
74-89-5
220000-87-3
Synthesis of 4-Chloro-N-methylpicolinamide from Methyl 4-chloropicolinate and Methylamine

4-Chloro-N-methylpicolinamide Preparation Products And Raw materials

Raw materials

Preparation Products

4-CHLORO-N,N-DIMETHYL-PYRIDINE-2-CARBOXAMIDE 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

4-Chloro-N-methylpicolinamide Suppliers

Global( 557)Suppliers
Supplier Tel Email Country ProdList Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd
+86-18752526868 jennysun@yzqyyykj.com China 81 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531153977 allison@yan-xi.com China 5855 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2472 58
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 970 58
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106 sales@frappschem.com China 880 50
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29792 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21632 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3009 60
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Supplier Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd
58
Hebei Yanxi Chemical Co., Ltd. 		58
Henan Bao Enluo International TradeCo.，LTD 		58
hebei hongtan Biotechnology Co., Ltd 		58
Frapp's ChemicalNFTZ Co., Ltd. 		50
Capot Chemical Co.,Ltd. 		60
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
Nanjing Finetech Chemical Co., Ltd. 		55

View Lastest Price from 4-Chloro-N-methylpicolinamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Methyl-4-chloropyridine-2-carboxamide pictures 2025-02-14 N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
 US $12.00 / KG 1KG 99% 100mt Jinan Finer Chemical Co., Ltd
N-Methyl-4-chloropyridine-2-carboxamide pictures 2025-02-12 N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
 US $0.00-0.00 / g 10g 99%min 10000g WUHAN FORTUNA CHEMICAL CO., LTD
N-Methyl-4-chloropyridine-2-carboxamide pictures 2025-02-11 N-Methyl-4-chloropyridine-2-carboxamide
220000-87-3
 US $30.00 / kg 1kg 98% 2000kg hebei hongtan Biotechnology Co., Ltd

4-Chloro-N-methylpicolinamide Spectrum

N-Methyl-4-chloropyridine-2-carboxamide(220000-87-3)1HNMR

220000-87-3(4-Chloro-N-methylpicolinamide)Related Search:

Methylparaben N,N-Dimethylformamide Thiophanate-methyl Kresoxim-methyl Methyl acrylate
Methyl acetate Bensulfuron methyl N-Methylformamide 2-Picoline PYRIDINE-2-CARBOXAMIDE
2,2'-(Butylimino)diethanol N-Benzylethanolamine 3-Amino-2-chlorobenzotrifluoride Methyl Sorafenib IMpurity
Sorafenib related coMpound 8 Sorafenib related compound 10 Sorafenib Related Compound 21

1of4

IFLAB-BB F2108-0189 N-METHYL-4-CHLORO-PYRIDINE-2-CARBOXAMIDE 4-CHLORO-N-MENTHYLPHCOLINAMIDE 4-Chloropyridine-2-carboxylic acid methylamide N-Methyl-4-chloro-2-pyridinecarboxamide N-Methyl-4-chloropicolinamide 4-Chloro-(2-(methylamino)-carbonyl)-pyridine N-Methyl-4-chloropyridine-2-carboxylate 4-chloro-n-Methyl-2-pyriMidine carboxaMide 2-PyridinecarboxaMide, 4-chloro-N-Methyl- 2-(N-MethylcarbaMoyl)-4-chloropyridine 4-Chloro-N-Methylpyridine-2-CarboxaMide 2-carboxaMide 4-Chloro-N-Methylpyridine-2-carboxaMide (>90%) 4-Chloro-N-Methyl-2-pyridinecarboxaMide, >95% 4-Chloro-N-methylpyridine-2-carboxamide Sorafenib INT3 4-Chloropyridine-2 4-Chloro-N-methyl-2-pyridinecarboxamide Sorafenib Intermediates I Sorafenib tosylate INT II 4-Chloro-N-methyl-2-pyridinecarboxamide 97% 4-Chloro-N-methyl-2-pyridinecarboxamide > oro-N-methyL -2-pyridinecarboxamide 4-CHLORO-N-METHYL-2-PYRIDENECARBOXAMIDE N-Methyl-4-chloropyridine-2-carboxamide ISO 9001：2015 REACH Sorafenib tosylate Impurity P 4-Chloro-N-methyl-2-pyridinecarboxamide (Sorafenib Impurity) Sorafenib impurities13 (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide)Q: What is (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What is the CAS Number of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What is the storage condition of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What are the applications of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) N-Methyl-4-chloropyridine-2-carboxamide(220000-87-3) 4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE 4-Chloro-N-methylpicolinamide 4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE 4-Chloro-N-methylpyridine-2-carboxamide,97% N-methyl-4-chloro-2-pyridinecarbonamide Sorafenib Impurity INT-1-B CAS:220000-87-3 220000-87-3 Pyridine Amines Aromatics Heterocycles blocks Carboxes Pyridines 220000-87-3