aciculatin
- CAS No.
- 134044-97-6
- Chemical Name:
- aciculatin
- Synonyms
- aciculatin;4H-1-Benzopyran-4-one, 8-(2,6-dideoxy-β-D-ribo-hexopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-
- CBNumber:
- CB61352467
- Molecular Formula:
- C22H22O8
- Molecular Weight:
- 414.41
- MDL Number:
- MOL File:
- 134044-97-6.mol
aciculatin Chemical Properties,Uses,Production
Description
Aciculatin, a natural compound extracted from the medicinal herb Chrysopogon aciculatus, shows potent anti-cancer potency. Aciculatin treatment induces cell cycle arrest and apoptosis via inhibition of MDM2 expression, thereby inducing p53 accumulation without significant DNA damage and genome toxicity.
Uses
Aciculatin is a compound with cytotoxic, anti-inflammatory and anti-arthritic activities, and its synthetic route including specific chemical reaction steps was determined through the first total synthesis.
Definition
ChEBI: Aciculatin is a member of flavonoids and a C-glycosyl compound.
References
[1] Total Synthesis of the Naturally Occurring Glycosylflavone Aciculatin DOI:10.1021/acs.jnatprod.5b01051
aciculatin Preparation Products And Raw materials
aciculatin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32239 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |