ChemicalBook >> CAS DataBase List >>aciculatin

aciculatin

CAS No.
134044-97-6
Chemical Name:
aciculatin
Synonyms
aciculatin;4H-1-Benzopyran-4-one, 8-(2,6-dideoxy-β-D-ribo-hexopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-
CBNumber:
CB61352467
Molecular Formula:
C22H22O8
Molecular Weight:
414.41
MDL Number:
MOL File:
134044-97-6.mol
Last updated:2025-04-18 09:51:20

aciculatin Properties

LogP 1.928 (est)

aciculatin Chemical Properties,Uses,Production

Description

Aciculatin, a natural compound extracted from the medicinal herb Chrysopogon aciculatus, shows potent anti-cancer potency. Aciculatin treatment induces cell cycle arrest and apoptosis via inhibition of MDM2 expression, thereby inducing p53 accumulation without significant DNA damage and genome toxicity.

Uses

Aciculatin is a compound with cytotoxic, anti-inflammatory and anti-arthritic activities, and its synthetic route including specific chemical reaction steps was determined through the first total synthesis.

Definition

ChEBI: Aciculatin is a member of flavonoids and a C-glycosyl compound.

References

[1] Total Synthesis of the Naturally Occurring Glycosylflavone Aciculatin DOI:10.1021/acs.jnatprod.5b01051

90-24-4
134044-97-6
Synthesis of aciculatin from 2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE

aciculatin Preparation Products And Raw materials

Raw materials

Preparation Products

aciculatin Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32250 58
Supplier Advantage
TargetMol Chemicals Inc.
58
aciculatin 4H-1-Benzopyran-4-one, 8-(2,6-dideoxy-β-D-ribo-hexopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy- 134044-97-6