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Papaveretum

CAS No.
8002-76-4
Chemical Name:
Papaveretum
Synonyms
Papaveretum
CBNumber:
CB61402360
Molecular Formula:
C55H64Cl3N3O10
Molecular Weight:
1033.46976
MDL Number:
MOL File:
8002-76-4.mol
Last updated:2023-05-27 10:32:18

Papaveretum Properties

ATC code N02AA10

Pharmacokinetic data

Protein binding 90 20-35 7%
Excreted unchanged in urine 1 10 <5%
Volume of distribution 0.99-1.52 3-5 3-4(L/kg)
Biological half-life 1.2-2.2 / - 2-3 / Unchanged 2.5-4 / -

SAFETY

Risk and Safety Statements

RIDADR  1544
HazardClass  6.1(a)
PackingGroup  II

Papaveretum Chemical Properties,Uses,Production

Clinical Use

Opiate analgesia (15.4 mg/mL) 1 mL contains 10 mg anhydrous morphine, 1.2 mg papaverine HCl, and 1.04 mg codeine HCl

Drug interactions

Potentially hazardous interactions with other drugs
Analgesics: possible opioid withdrawal with buprenorphine and pentazocine.
Anti-arrhythmics: delayed absorption of mexiletine.
Antidepressants: possible CNS excitation or depression with MAOIs – avoid; possible CNS excitation or depression with moclobemide; increased sedative effects with tricyclics.
Antihistamines: increased sedative effects with sedating antihistamines.
Antipsychotics: enhanced hypotensive and sedative effects.
Dopaminergics: avoid with selegiline.
Nalmefene: avoid concomitant use.
Sodium oxybate: enhanced effect of sodium oxybate – avoid.

Metabolism

Papaverine: Mainly metabolised in the liver and excreted in the urine, almost entirely as glucuronide-conjugated phenolic metabolites.

Papaveretum Preparation Products And Raw materials

Raw materials

Preparation Products

Papaveretum Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhuhai Anzhe Biotechnology Co,Ltd. 13169972583 513211116@qq.com China 3015 58
Supplier Advantage
Zhuhai Anzhe Biotechnology Co,Ltd. 58
Papaveretum 8002-76-4