L-KYNURENINE
- CAS No.
- 2922-83-0
- Chemical Name:
- L-KYNURENINE
- Synonyms
- CCRIS 4425;L-KYNURENINE;JACS-2922-83-0;(S)-Kynurenine;Kynurenine (L);L-Kynurenine L-Kynurenine Hydrate;L-kynurenine free base;L-KynurenineHydrate>L-KYNURENINE USP/EP/BP
- CBNumber:
- CB6142966
- Molecular Formula:
- C10H12N2O3
- Molecular Weight:
- 208.21
- MDL Number:
- MFCD00069912
- MOL File:
- 2922-83-0.mol
- MSDS File:
- SDS
Melting point | 219 °C |
---|---|
Boiling point | 466.6±45.0 °C(Predicted) |
Density | 1.343±0.06 g/cm3(Predicted) |
refractive index | -33 ° (C=0.4, H2O) |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml). |
form | crystalline |
pka | 2.21±0.23(Predicted) |
color | light yellow |
Merck | 14,5328 |
Stability | Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months. |
InChIKey | YGPSJZOEDVAXAB-QMMMGPOBSA-N |
CAS DataBase Reference | 2922-83-0(CAS DataBase Reference) |
FDA UNII | 02JW4J5R44 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
WGK Germany | 3 |
RTECS | CY9049700 |
HS Code | 2922500090 |
L-KYNURENINE price More Price(36)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | K8625 | L-Kynurenine ≥98% (HPLC) | 2922-83-0 | 25mg | $72.7 | 2024-03-01 | Buy |
Sigma-Aldrich | K8625 | L-Kynurenine ≥98% (HPLC) | 2922-83-0 | 1g | $518 | 2024-03-01 | Buy |
TCI Chemical | K0016 | L-Kynurenine Hydrate >98.0%(T) | 2922-83-0 | 100mg | $127 | 2024-03-01 | Buy |
Alfa Aesar | J60199 | L-Kynurenine | 2922-83-0 | 50mg | $79.7 | 2024-03-01 | Buy |
Cayman Chemical | 11305 | Kynurenine ≥98% | 2922-83-0 | 50mg | $37 | 2024-03-01 | Buy |
L-KYNURENINE Chemical Properties,Uses,Production
Description
Kynurenine (2922-83-0) is a tryptophan catabolite.1?Endogenous tumor-promoting ligand of the human aryl hydrocarbon receptor (AhR). Constitutively generated by human tumor cells via the action of the tryptophan degrading enzyme, tryptophan-2,3-dioxygenase (TDO). Kynurenine suppresses antitumor immune responses and promotes tumor cell survival and motility.2
Uses
L-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media.
Definition
ChEBI: A kynurenine that has L configuration.
Biochem/physiol Actions
Key intermediate in the breakdown pathway of tryptophan.
storage
Store at RT
References
References/Citations 1) Ibana?et al. (2011),?Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlaydia trachomatis persistence in human epithelial cells; Infect. Immun.,?79?4425 2) Opitz?et al. (2011),?An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor; Nature,?478?197
L-KYNURENINE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13214 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
View Lastest Price from L-KYNURENINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2021-07-02 | L-kynurenine
2922-83-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
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2019-12-31 | L-KYNURENINE
2922-83-0
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co | |
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2019-12-31 | L-KYNURENINE
2922-83-0
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- L-kynurenine
2922-83-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- L-KYNURENINE
2922-83-0
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
-
- L-KYNURENINE
2922-83-0
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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