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L-KYNURENINE

L-KYNURENINE structure

CAS No.: 2922-83-0

Chemical Name:: L-KYNURENINE

Synonyms: CCRIS 4425;L-KYNURENINE;JACS-2922-83-0;(S)-Kynurenine;Kynurenine (L);L-Kynurenine L-Kynurenine Hydrate;L-kynurenine free base;L-KynurenineHydrate>L-KYNURENINE USP/EP/BP

CBNumber:: CB6142966

Molecular Formula:: C10H12N2O3

Molecular Weight:: 208.21

MDL Number:: MFCD00069912

MOL File:: 2922-83-0.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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L-KYNURENINE Properties

Melting point	219 °C
Boiling point	466.6±45.0 °C(Predicted)
Density	1.343±0.06 g/cm3(Predicted)
refractive index	-33 ° (C=0.4, H2O)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
form	crystalline
pka	2.21±0.23(Predicted)
color	light yellow
optical activity	-30.525 (H2O)
Merck	14,5328
Stability	Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey	YGPSJZOEDVAXAB-QMMMGPOBSA-N
CAS DataBase Reference	2922-83-0(CAS DataBase Reference)
FDA UNII	02JW4J5R44

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany	3
RTECS	CY9049700
HS Code	2922500090

L-KYNURENINE price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	K8625	L-Kynurenine ≥98% (HPLC)	2922-83-0	25mg	$72.7	2024-03-01	Buy
Sigma-Aldrich	K8625	L-Kynurenine ≥98% (HPLC)	2922-83-0	1g	$518	2024-03-01	Buy
TCI Chemical	K0016	L-Kynurenine Hydrate >98.0%(T)	2922-83-0	100mg	$127	2024-03-01	Buy
Alfa Aesar	J60199	L-Kynurenine	2922-83-0	50mg	$79.7	2024-03-01	Buy
Cayman Chemical	11305	Kynurenine ≥98%	2922-83-0	50mg	$37	2024-03-01	Buy

Product number	Packaging	Price	Buy
K8625	25mg	$72.7	Buy
K8625	1g	$518	Buy
K0016	100mg	$127	Buy
J60199	50mg	$79.7	Buy
11305	50mg	$37	Buy

L-KYNURENINE Chemical Properties,Uses,Production

Description

Kynurenine (2922-83-0) is a tryptophan catabolite.1?Endogenous tumor-promoting ligand of the human aryl hydrocarbon receptor (AhR). Constitutively generated by human tumor cells via the action of the tryptophan degrading enzyme, tryptophan-2,3-dioxygenase (TDO). Kynurenine suppresses antitumor immune responses and promotes tumor cell survival and motility.2

Uses

L-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media.

Definition

ChEBI: A kynurenine that has L configuration.

Biochem/physiol Actions

Key intermediate in the breakdown pathway of tryptophan.

storage

Store at RT

References

References/Citations 1) Ibana?et al. (2011),?Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlaydia trachomatis persistence in human epithelial cells; Infect. Immun.,?79?4425 2) Opitz?et al. (2011),?An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor; Nature,?478?197

L-KYNURENINE synthesis

Synthesis of L-KYNURENINE from 2-Iodoaniline

L-KYNURENINE Preparation Products And Raw materials

Raw materials

Benzenebutanoic acid, 2-amino-α-[[(1,1-dimethylethoxy)carbonyl]amino]-γ-oxo-, methyl ester, (αS)- 1H-Indole-3-propanoic acid, α-amino-2,3-dihydro-2-oxo-, (αS)- DL-KYNURENINE D-KYNURENINE 2-Iodoaniline

L-Tryptophan

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Preparation Products

Tryptamine 4-HYDROXY-1-METHYL-2-QUINOLONE

L-KYNURENINE Suppliers

Global( 223)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11817	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Biochempartner	58
Hubei Jusheng Technology Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58

View Lastest Price from L-KYNURENINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	L-Kynurenine 2922-83-0	US $56.00-40.00 / mg		99.91%	10g	TargetMol Chemicals Inc.
2021-07-02	L-kynurenine 2922-83-0	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-12-31	L-KYNURENINE 2922-83-0	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

L-Kynurenine
2922-83-0
US $56.00-40.00 / mg
99.91%
TargetMol Chemicals Inc.

L-kynurenine
2922-83-0
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

L-KYNURENINE
2922-83-0
US $7.00 / KG
99%
Career Henan Chemical Co

L-KYNURENINE Spectrum

L-KYNURENINE(2922-83-0)MS L-KYNURENINE(2922-83-0)¹³CNMR L-KYNURENINE(2922-83-0)IR1 L-KYNURENINE(2922-83-0)IR2

2922-83-0(L-KYNURENINE)Related Search:

3-HYDROXY-L-KYNURENINE 2-(3-INDOLYLMETHYL)-L-TRYPTOPHAN 2-Hydroxy-DL-tryptophan 2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-3-CARBOXYLIC ACID HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID

Tryptophan EP Impurity L Tryptophan EP Impurity F PEAK E Tryptophan EP Impurity D Tryptophan EP Impurity J

N'-formyl-L-Kynurenine Dioxindolyl-L-alanine 5-Hydroxytryptophan 3-(phenylamino)alanine D-1,2,3,4-tetrahydronorharmane-3-carboxylic acid

N-formylkynurenine H-PHE-TRP-OH L-Isovaline

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L-2-AMINO-3-(2-AMINOBENZOYL)PROPIONIC ACID L-2-AMINO-4-[2-AMINOPHENYL]-4-OXOBUTANOIC ACID L-KYNURENINE L-kynurenine free base β-Anthraniloyl-L-alanine β-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid L-Kynurenine Hydrate (S)-2-Amino-4-oxo-4-(2-aminophenyl)butanoic acid (S)-α,2-Diamino-γ-oxobenzenebutanoic acid 3-(2-Aminobenzoyl)alanine 3-(2-Aminobenzoyl)-L-alanine (2S)-2-amino-4-(2-aminophenyl)-4-keto-butyric acid (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid (2S)-2-azanyl-4-(2-azanylphenyl)-4-oxo-butanoic acid Benzenebutanoic acid, a,2-diaMino-g-oxo-, (aS)- (S)-2-AMino-4-(2-aMinophenyl)-4-oxobutanoic acid L-3-(o-Aminobenzoyl)alanine L-Kynurenine L-Kynurenine Hydrate L-KYNURENINE, >=98% (HPLC) Tryptophan Impurity 3（Tryptophan EP Impurity C） JACS-2922-83-0 Tryptophan EP Impurity C L-KynurenineHydrate> (S)-Kynurenine Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)- L-KYNURENINE USP/EP/BP N-Acetyltryptophan EP Impurity C Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)- Kynurenine (L) c.?(S)-2-amino-4-(2-aminophenyl)-4-oxobutanoicacid(kynurenine), L-Kynurenine (Tryptophan Impurity) CCRIS 4425 β-Anthraniloyl-L-alanine Tryptophan - Impurity C 2922-83-0 C10H12N2O313H2O C10H12N2O3xH2O Amino Acid BioChemical Metabolomics Metabolites and Cofactors on the Metabolic Pathways Chart Metabolic Pathways Amino Acids Amino Acids Biochemistry non-Proteinorganic Amino Acids