3-Hydroxy-2-nitropyridine
- CAS No.
- 15128-82-2
- Chemical Name:
- 3-Hydroxy-2-nitropyridine
- Synonyms
- 2-Nitro-pyridin-3-ol;NSC 97501;2-nitro-3-pyridino;TIMTEC-BB SBB004168;2-NITRO-3-PYRIDINOL;3-Hydroxy-2-nitropyr;3-PYRIDINOL, 2-NITRO-;Crizotinib Impurity 8;2-nitro-3-pyridinolate;2-NITRO-3-HYDROPYRIDINE
- CBNumber:
- CB6145215
- Molecular Formula:
- C5H4N2O3
- Molecular Weight:
- 140.1
- MDL Number:
- MFCD00006258
- MOL File:
- 15128-82-2.mol
- MSDS File:
- SDS
Melting point | 69-71 °C (lit.) |
---|---|
Boiling point | 256.56°C (rough estimate) |
Density | 1.5657 (rough estimate) |
refractive index | 1.4800 (estimate) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
pka | 0.31±0.22(Predicted) |
form | Crystalline Powder |
color | Yellow |
BRN | 124473 |
InChIKey | QBPDSKPWYWIHGA-UHFFFAOYSA-N |
CAS DataBase Reference | 15128-82-2(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | UU357X85YB |
EPA Substance Registry System | 3-Hydroxy-2-nitropyridine (15128-82-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-37/39-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | UU7715000 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29333990 | |||||||||
Toxicity | mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04089, | |||||||||
NFPA 704 |
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3-Hydroxy-2-nitropyridine price More Price(38)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 107255 | 3-Hydroxy-2-nitropyridine 97% | 15128-82-2 | 25g | $49.6 | 2023-06-20 | Buy |
Sigma-Aldrich | 107255 | 3-Hydroxy-2-nitropyridine 97% | 15128-82-2 | 100g | $188 | 2023-06-20 | Buy |
TCI Chemical | H0764 | 3-Hydroxy-2-nitropyridine >98.0%(GC)(T) | 15128-82-2 | 25g | $150 | 2024-03-01 | Buy |
Alfa Aesar | A14887 | 3-Hydroxy-2-nitropyridine, 98% | 15128-82-2 | 10g | $39.65 | 2024-03-01 | Buy |
Alfa Aesar | A14887 | 3-Hydroxy-2-nitropyridine, 98% | 15128-82-2 | 50g | $129.65 | 2024-03-01 | Buy |
3-Hydroxy-2-nitropyridine Chemical Properties,Uses,Production
Chemical Properties
yellow crystalline powder
Uses
3-Hydroxy-2-nitropyridine may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization.
Preparation
Synthesis of 3-hydroxy-2-nitropyridine: add 10g of 3-hydroxypyridine, 80ml of ethyl acetate, 4.2g of KNO3 and 21ml of acetic anhydride into a 250mL three-necked flask, and heat at 45°C with magnetic stirring After the reaction is completed, it is cooled to room temperature, filtered with suction, washed with a small amount of ethyl acetate for 1 to 2 times, the filtrate is taken to adjust the pH to neutrality with saturated NaOH solution, and extracted with ethyl acetate for 3 to 4 times. , take the extract and add activated carbon and heat under reflux for 1 hour, cool and filter, take the filtrate, dry with anhydrous magnesium sulfate, filter, concentrate on a rotary evaporator, and dry in a drying oven. 11.9 g of 3-hydroxy-2-nitropyridine was obtained with a yield of 81%.
3-Hydroxy-2-nitropyridine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20284 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
View Lastest Price from 3-Hydroxy-2-nitropyridine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-23 | 2-Nitro-3-pyridinol
15128-82-2
|
US $60.00-50.00 / box | 1box | 99.99% | 500 box | hebei hongtan Biotechnology Co., Ltd | ||
2024-10-11 | 3-Hydroxy-2-nitropyridine
15128-82-2
|
US $20.00 / kg | 1kg | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-02-26 | 3-Hydroxy-2-nitropyridine
15128-82-2
|
US $0.00-0.00 / kg | 1kg | 98% | Kgs | BTC Nantong Pharmaceuticals Technology Co.,Ltd |
- 2-Nitro-3-pyridinol
15128-82-2
- US $60.00-50.00 / box
- 99.99%
- hebei hongtan Biotechnology Co., Ltd
- 3-Hydroxy-2-nitropyridine
15128-82-2
- US $20.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- 3-Hydroxy-2-nitropyridine
15128-82-2
- US $0.00-0.00 / kg
- 98%
- BTC Nantong Pharmaceuticals Technology Co.,Ltd
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