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3-Hydroxy-2-nitropyridine

CAS No.
15128-82-2
Chemical Name:
3-Hydroxy-2-nitropyridine
Synonyms
2-Nitro-pyridin-3-ol;NSC 97501;2-nitro-3-pyridino;TIMTEC-BB SBB004168;2-NITRO-3-PYRIDINOL;3-Hydroxy-2-nitropyr;3-PYRIDINOL, 2-NITRO-;Crizotinib Impurity 8;2-nitro-3-pyridinolate;2-NITRO-3-HYDROPYRIDINE
CBNumber:
CB6145215
Molecular Formula:
C5H4N2O3
Molecular Weight:
140.1
MDL Number:
MFCD00006258
MOL File:
15128-82-2.mol
MSDS File:
SDS
Last updated:2024-12-18 14:15:30

3-Hydroxy-2-nitropyridine Properties

Melting point 69-71 °C (lit.)
Boiling point 256.56°C (rough estimate)
Density 1.5657 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka 0.31±0.22(Predicted)
form Crystalline Powder
color Yellow
BRN 124473
InChIKey QBPDSKPWYWIHGA-UHFFFAOYSA-N
CAS DataBase Reference 15128-82-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII UU357X85YB
EPA Substance Registry System 3-Hydroxy-2-nitropyridine (15128-82-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36
WGK Germany  3
RTECS  UU7715000
Hazard Note  Irritant
HS Code  29333990
Toxicity mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04089,
NFPA 704
1
2 0

3-Hydroxy-2-nitropyridine price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 107255 3-Hydroxy-2-nitropyridine 97% 15128-82-2 25g $49.6 2023-06-20 Buy
Sigma-Aldrich 107255 3-Hydroxy-2-nitropyridine 97% 15128-82-2 100g $188 2023-06-20 Buy
TCI Chemical H0764 3-Hydroxy-2-nitropyridine >98.0%(GC)(T) 15128-82-2 25g $150 2024-03-01 Buy
Alfa Aesar A14887 3-Hydroxy-2-nitropyridine, 98% 15128-82-2 10g $39.65 2024-03-01 Buy
Alfa Aesar A14887 3-Hydroxy-2-nitropyridine, 98% 15128-82-2 50g $129.65 2024-03-01 Buy
Product number Packaging Price Buy
107255 25g $49.6 Buy
107255 100g $188 Buy
H0764 25g $150 Buy
A14887 10g $39.65 Buy
A14887 50g $129.65 Buy

3-Hydroxy-2-nitropyridine Chemical Properties,Uses,Production

Chemical Properties

yellow crystalline powder

Uses

3-Hydroxy-2-nitropyridine may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization.

Preparation

Synthesis of 3-hydroxy-2-nitropyridine: add 10g of 3-hydroxypyridine, 80ml of ethyl acetate, 4.2g of KNO3 and 21ml of acetic anhydride into a 250mL three-necked flask, and heat at 45°C with magnetic stirring After the reaction is completed, it is cooled to room temperature, filtered with suction, washed with a small amount of ethyl acetate for 1 to 2 times, the filtrate is taken to adjust the pH to neutrality with saturated NaOH solution, and extracted with ethyl acetate for 3 to 4 times. , take the extract and add activated carbon and heat under reflux for 1 hour, cool and filter, take the filtrate, dry with anhydrous magnesium sulfate, filter, concentrate on a rotary evaporator, and dry in a drying oven. 11.9 g of 3-hydroxy-2-nitropyridine was obtained with a yield of 81%.

109-00-2
15128-82-2
Synthesis of 3-Hydroxy-2-nitropyridine from 3-Hydroxypyridine
Global( 512)Suppliers
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Hebei Chuanghai Biotechnology Co,.LTD
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View Lastest Price from 3-Hydroxy-2-nitropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Nitro-3-pyridinol  pictures 2024-12-23 2-Nitro-3-pyridinol
15128-82-2
US $60.00-50.00 / box 1box 99.99% 500 box hebei hongtan Biotechnology Co., Ltd
3-Hydroxy-2-nitropyridine pictures 2024-10-11 3-Hydroxy-2-nitropyridine
15128-82-2
US $20.00 / kg 1kg 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
3-Hydroxy-2-nitropyridine pictures 2024-02-26 3-Hydroxy-2-nitropyridine
15128-82-2
US $0.00-0.00 / kg 1kg 98% Kgs BTC Nantong Pharmaceuticals Technology Co.,Ltd
2-nitro-3-pyridino 3-HYDROXY-2-NITROPYRIDINE 3-PYRIDINOL, 2-NITRO- 2-NITRO-3-PYRIDINOL 3-Hydroxy-2-Nitro Pyridine 2-Nitro-3-Hydroxy Pyridine 3-HYDROXY-2-NITROPYRIDINE 97% TIMTEC-BB SBB004168 3-Hydroxy-2-Nitropyrine 2-NITRO-3-HYDROPYRIDINE 3-Pyridinol,2-nitro-(6CI,8CI,9CI) 3-HYDROXY-2-NITROPYRIDINE 98+% 3-Hydroxy-2-nitropyridine,97% 3-Hydroxy-2-nitropyr 3-Hydroxy-2-nitropyridine, 97% 100GR 3-Hydroxy-2-nitropyridine, 97% 25GR NSC 97501 2-nitro-3-pyridinolate Crizotinib Impurity 8 3-Hydroxy-2-nitropyridine> 3-Hydroxy-2-nitropyridine ISO 9001:2015 REACH 2-Nitro-pyridin-3-ol 15128-82-2 15128-82-0 15128-37-6 C5H4N2O3 Building Blocks C5 Heterocyclic Building Blocks Pyridines Pyridines, Pyrimidines, Purines and Pteredines Pyridine Pyridines derivates CHIRAL CHEMICALS NITRO blocks NitroCompounds Pyridines Heterocycles 15128-82-2