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4-Chlorobenzhydrol

CAS No.
119-56-2
Chemical Name:
4-Chlorobenzhydrol
Synonyms
Chlorobenzhydrol;Cetirizine 4-Chlorobenzhydrol Impurity;AURORA KA-7061;4-CHLOROBENZHYDROL;Meclizine USP RC A;P-CHLORO BENZHYDROL;4-Chlorobenzohydrol;p-Chlorobenzohydrol;Benzhydrol, p-chloro-;Benzhydrol, 4-chloro-
CBNumber:
CB6151432
Molecular Formula:
C13H11ClO
Molecular Weight:
218.68
MDL Number:
MFCD00004491
MOL File:
119-56-2.mol
Last updated:2024-11-01 18:09:03

4-Chlorobenzhydrol Properties

Melting point 58-60 °C (lit.)
Boiling point 150-151°C 2,6mm
Density 1.1178 (rough estimate)
refractive index 1.5260 (estimate)
Flash point 150-151°C/2.6mm
storage temp. 2-8°C
solubility insoluble
pka 13.34±0.20(Predicted)
color White to Off-White
Water Solubility insoluble
BRN 2050235
CAS DataBase Reference 119-56-2(CAS DataBase Reference)
FDA UNII V5V8VYQ65X
NIST Chemistry Reference Benzenemethanol, 4-chloro-«alpha»-phenyl-(119-56-2)
EPA Substance Registry System Benzenemethanol, 4-chloro-.alpha.-phenyl- (119-56-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273-P501
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
TSCA  Yes
HS Code  29062990
NFPA 704
0
1 0

4-Chlorobenzhydrol price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3034 Meclizine Related Compound A pharmaceutical secondary standard, certified reference material 119-56-2 30MG $460 2024-03-01 Buy
Sigma-Aldrich 1377010 Meclizine Related Compound A United States Pharmacopeia (USP) Reference Standard 119-56-2 15mg $1490 2024-03-01 Buy
Sigma-Aldrich 124982 4-Chlorobenzhydrol 98% 119-56-2 1g $12.48 2024-03-01 Buy
TCI Chemical C0989 4-Chlorobenzhydrol >98.0%(GC) 119-56-2 25g $36 2024-03-01 Buy
TCI Chemical C0989 4-Chlorobenzhydrol >98.0%(GC) 119-56-2 500g $349 2024-03-01 Buy
Product number Packaging Price Buy
PHR3034 30MG $460 Buy
1377010 15mg $1490 Buy
124982 1g $12.48 Buy
C0989 25g $36 Buy
C0989 500g $349 Buy

4-Chlorobenzhydrol Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

4-Chlorobenzhydrol was used as internal standard to measure the N-demethyl antipyrine metabolite in urine by gas chromatography-mass spectrometry. It was also used in the identification of the antihistamine cetirizine as a relevant cross-reactant for the carbamazepine-specific enzyme-linked immunosorbent assay .

Definition

ChEBI: P-Chlorobenzhydrol is a diarylmethane.

Preparation

Preparation of 4-Chlorobenzhydrol(4-CB):
about 5.0g(0.023 mol) of 4-chloro benzophenone was dissolved in 15 mL of isopropyl alcohol (IPA) and heated to 50°C followed by the addition of 0.265g(0.007 mol) of sodium borohydride as a lot with the temperature maintained at 65°C for 2 h. The reaction mixture was distilled to expel isopropyl alcohol up to 90 %. The resulting solution was cooled and treated with dil HCl (5 mL of conc. HCl in 20 mL of water). Finally the reaction mass was extracted with 15 mL of toluene. The toluene extract was washed withwater to pH-7. The compound obtained in this step was taken to next step without isolation but aliquot sample was concentrated, isolated and checked for melting point (m.p. = 58-60°C).

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View Lastest Price from 4-Chlorobenzhydrol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chlorobenzhydrol pictures 2024-11-01 4-Chlorobenzhydrol
119-56-2
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
4-Chlorobenzhydrol pictures 2024-10-25 4-Chlorobenzhydrol
119-56-2
US $30.00-10.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
4-Chlorobenzhydrol pictures 2022-02-25 4-Chlorobenzhydrol
119-56-2
US $99.00 / KG 1KG 99% 1 ton Hong Kong Tiansheng New Material Trading Co., Ltd
  • 4-Chlorobenzhydrol pictures
  • 4-Chlorobenzhydrol
    119-56-2
  • US $99.00 / KG
  • 99%
  • Hong Kong Tiansheng New Material Trading Co., Ltd
(4-Chlorophenyl)phenylmethanol 4-chloro-alpha-phenyl-benzenemethano 4-Chlorobenzohydrol Benzhydrol, 4-chloro- Benzhydrol, p-chloro- AURORA KA-7061 P-CHLORO BENZHYDROL 4-CHLOROPHENYL PHENYL CARBINOL 4-CHLORO-ALPHA-PHENYL-BENZENEMETHANOL 4-CHLORO-(ALPHA-PHENYL) BENZYL ALCOHOL 4-CHLOROBENZHYDROL 4-Chlorobenzhydryl alcohol 4-CHLORO-O-PHENYLBENZYL ALCOHOL 4-CHLORODIPHENYLCARBINOL 4-CHLORODIPHENYLMETHANOL Benzenemethanol, 4-chloro-.alpha.-phenyl- 4-Chlorodiphenylmethanol~4-Chlororphenyl phenyl carbinol 4-CHLOROBENZHYDROL 98+% 4-Chloro-a-phenyl-benzenemethanol 4-CHLOROBENZHYDROL pure 4-Chloro-α-phenylbenzenemethanol (p-Chlorophenyl)phenylmethanol p-Chlorobenzohydrol Phenyl(4-chlorophenyl)methanol Meclizine Related Compound A (15 mg) (4-chlorobenzhydrol) 4-CHLOROBENZHYDROL FOR SYNTHESIS Buclizine HCl IMpurity-B(BP/EP) Levocetrizine IMpurity 4-Chloro Benzhydrol (Meclozine EP IMpurity B) Meclozine EP IMpurity B (4-Chlorobenzhydrol) BenzeneMethanol, 4-chloro-α-phenyl- Meclozine impurity B Cetirizine 4-Chlorobenzhydrol Impurity (USP) Meclizine USP RC A 4-Chlorobenzhydrol 98% Buclizine EP Impurity B (R)-(4-chlorophenyl)-phenylmethanol Cetirizine Impurity L Meclizine USP Related Compound A Cetirizine Impurity I 4-Chlorobenzhydrol > Meclozine impurity B CRS N-Methyl-2-(pyridin-2-yl)-N-[2-(pyr Levocloperastine CBZ Racemate Meclizine EP Impurity B Meclozine EP Impurity B Meclozine imp-B/4-Chlorobenzhydrol Cetirizine 4-Chlorobenzhydrol Impurity (Meclizine Related Compound A) Meclizine Related Compound A (Cetirizine 4-Chlorobenzhydrol Impurity) Cetrizine 4-chlorobenzyhydrol Impurity Cetirizine Impurity93 4-ChlorobenzhydrolQ: What is 4-Chlorobenzhydrol Q: What is the CAS Number of 4-Chlorobenzhydrol Q: What is the storage condition of 4-Chlorobenzhydrol Q: What are the applications of 4-Chlorobenzhydrol Chlorobenzhydrol Cetirizine 4-Chlorobenzhydrol Impurity Meclozine Dihydrochloride Impurity B Meclozine EP Impurity B (Meclizine USP Related Compound A, 4-Chlorobenzhydrol) Cinnarizine Impurity 12 Meclozine Dihydrochloride EP Impurity B