ChemicalBook >> CAS DataBase List >>(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

CAS No.
23735-43-5
Chemical Name:
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
Synonyms
(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate;(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE;Travoprost Impurity 51;(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE;L-α,β-Isopropylideneglycerol-γ-tosylate;(S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE;(S)-3-Toxyloxy-1,2-propanediol acetonide;2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE;(S)-1-O-tosyl-2,3-O-isopropylideneglycerol;(2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol
CBNumber:
CB6164890
Molecular Formula:
C13H18O5S
Molecular Weight:
286.34
MDL Number:
MFCD00063234
MOL File:
23735-43-5.mol
Last updated:2023-04-23 13:52:06

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Properties

Melting point 29-31 °C
alpha 4.2 º (c=10, abs.alcohol)
Boiling point 398.71°C (rough estimate)
Density 1.208 g/mL at 25 °C(lit.)
refractive index n20/D 1.506(lit.)
Flash point >230 °F
storage temp. Inert atmosphere,2-8°C
form powder to lump to clear liquid
color White or Colorless to Light yellow
optical activity [α]26/D +7.5°, c = 2% in DMF
BRN 89799
CAS DataBase Reference 23735-43-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
10-21
HS Code  29329990
NFPA 704
1
1 0

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 337420 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate 97% 23735-43-5 1g $171 2023-01-07 Buy
Sigma-Aldrich 337420 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate 97% 23735-43-5 5g $304 2023-01-07 Buy
TCI Chemical D2550 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate >98.0%(GC) 23735-43-5 1g $198 2024-03-01 Buy
TCI Chemical D2550 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate >98.0%(GC) 23735-43-5 5g $645 2024-03-01 Buy
TRC D469555 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate 23735-43-5 1g $115 2021-12-16 Buy
Product number Packaging Price Buy
337420 1g $171 Buy
337420 5g $304 Buy
D2550 1g $198 Buy
D2550 5g $645 Buy
D469555 1g $115 Buy

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 164)Suppliers
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(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE (S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE (S)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE (S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENSULFONATE (S)-(+)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL-4-METHYLBENZENESULFONATE 2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE 2,2-DIMETHYL-4(S)-4-(P-TOLYLSULFONYL)METHYL-1,3-DIOXALANE 1,3-DIOXOLANE-4-METHANOL, 2,2-DIMETHYL-, 4-METHYLBENZENESULFONATE, (4S)- L-α,β-Isopropylideneglycerol-γ-tosylate (S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOLUENE-4-SULFONATE (S)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-YLMETHYL P-TOLUENESULFONATE (S)-1,2-O-ISOPROPYLIDENEGLYCEROL-3-TOLUENESULFONATE (S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate (S)-3-Toxyloxy-1,2-propanediol acetonide (s)-2,2-dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol 4-toluenesulfo 2,3-Isopropylidene-sn-glycerol 1-tosylate, (S)-2,2-Dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate, L-α,β-Isopropylideneglycerol-γ-tosylate 2,3-Isopropylidene-sn-glycerol 1-tosylate, L-α,β-Isopropylideneglycerol-γ-tosylate (2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol 4-Methylbenzenesulfonic acid (S)-2,2-dimethyl-1,3-dioxolane-4α-ylmethyl ester p-Toluenesulfonic acid [(S)-2,2-dimethyl-1,3-dioxolane-4α-yl]methyl ester p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolan-4-ylmethyl ester p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolane-4-ylmethyl ester (S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate,97% L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL-GAMMA-TOSYLATE L-(+)-1,2-ISOPROPYLIDENEGLYCEROL 3-(P-TOLUENESULFONATE) (S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-tolue... (S)-(2,2-dimethyl-1,3-dioxalan-4-yl)methyl-4-methylbenzenesulfonate Travoprost Impurity 51 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-(4-methylbenzenesulfonate), (4S)- (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethylp-Toluenesulfonate> (4S)-2,2-dimethyl-4-(4-toluenesulphonyloxymethyl)-1,3-dioxolane (S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE (S)-1-O-tosyl-2,3-O-isopropylideneglycerol 23735-43-5 Asymmetric Synthesis Organic Building Blocks Protected Alcohols Dioxolanes Chiral Building Blocks Dioxanes & Dioxolanes Glycidyl Compounds, etc. (Chiral) chiral Chiral Building Blocks Dioxanes & Dioxolanes Dioxolanes Glycidyl Compounds, etc. (Chiral) Synthetic Organic Chemistry ADVANCED INT.