2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL
- CAS No.
- 1942-71-8
- Chemical Name:
- 2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL
- Synonyms
- propargite metab.;2-(p-t-butylphenoxy)cyclohexanol;2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL;2-(p-tert-butylphenoxy)-cyclohexano;CYCLOHEXANOL-2-(4-TERT-BUTYL-PHENOXY);2-(4-tert-butylphenoxy)-1-cyclohexanol;2-(4-tert-butylphenoxy)cyclohexan-1-ol;2-[4-(1,1-DIMETHYLETHYL)PHENOXY]CYCLOHEXANOL;C11825000 Cyclohexanol-2-(4-tert-butyl-phenox;Cyclohexanol, 2-[4-(1,1-dimethylethyl)phenoxy]-
- CBNumber:
- CB6174651
- Molecular Formula:
- C16H24O2
- Molecular Weight:
- 248.36
- MDL Number:
- MFCD00155433
- MOL File:
- 1942-71-8.mol
- MSDS File:
- SDS
| Melting point | 93-95 °C |
|---|---|
| Boiling point | 365.7±42.0 °C(Predicted) |
| Density | 1.036±0.06 g/cm3(Predicted) |
| storage temp. | Store at 4℃ |
| solubility | 24.84mg/ml in DMSO, 24.84mg/ml in Ethanol |
| pka | 14.60±0.40(Predicted) |
| form | powder |
| color | white to beige |
| FDA UNII | D498ND4OQG |
| EPA Substance Registry System | 2-(p-tert-Butylphenoxy)cyclohexanol (1942-71-8) |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Hazardous Substances Data | 1942-71-8(Hazardous Substances Data) |
|---|
2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0078071 | 2-(4-TERT-BUTYLPHENOXY) CYCLOHEXANOL 95.00% | 1942-71-8 | 5G | $909.56 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0078071 | 2-(4-TERT-BUTYLPHENOXY) CYCLOHEXANOL 95.00% | 1942-71-8 | 10G | $1334.03 | 2021-12-16 | Buy |
2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL Chemical Properties,Uses,Production
Uses
tBPC is a selective positive allosteric modulator for human Y4 receptor (Y4R), which enhances the activation of Y4R in G protein signaling and arrestin3 recruitment[1].
Biological Activity
tBPC is a postitive allosteric modulator of the neuropeptide Y (NPY) Y4 receptor, which is predominantly expressed in the gastrointestinal tract and activated most strongly by pancreatic polypeptide (PP). tBPC was shown to potentiate Y4R activity in G-Protein signaling and arrestin3 recruitment and to potentiate the native PP response. tBPC was selective for Y4R over other Neuropeptide Y receptors and showed no effect on the efficacy (Emax) or potency (EC50) of the NPY signal response at the Y1, Y2, or Y5 receptors at 30 μM.
References
[1] Schubert M, et al., Identification and Characterization of the First Selective Y4 Receptor Positive Allosteric Modulator. J Med Chem. 2017 Sep 14;60(17):7605-7612. DOI:10.1021/acs.jmedchem.7b00976
2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL Preparation Products And Raw materials
Raw materials
Preparation Products
2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL Suppliers
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