(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
- CAS No.
- 118102-98-0
- Chemical Name:
- (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
- Synonyms
- THYROID, BOVINE;D-Trp12,Tyr34]-bPTH-(7-34)NH2;(D-Trp12,Tyr34)-pTH (7-34) amide;(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE);DTrp12, Tyr34]-pTH(7-34), -Parathyroid Hor;DTrp12, Tyr34]-Parathyroid Hormone(7-34), -Parath;(D-Trp??,Tyr??)-pTH (7-34) amide (bovine) trifluoroacetate salt;PHE-MET-HIS-ASN-LEU-D-TRP-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-TYR-NH2;H-PHE-MET-HIS-ASN-LEU-D-TRP-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-TYR-NH2
- CBNumber:
- CB6200161
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00081220
- MOL File:
- Mol file
| storage temp. | -15°C |
|---|---|
| solubility | Soluble in DMSO |
| form | Solid |
| color | White to off-white |
| Sequence | Phe-Met-His-Asn-Leu-{d-Trp}-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2 |
| FDA UNII | MN18OTN73W |
(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | T5348-05B | Thyroid, Bovine | 118102-98-0 | 25Ea | $329 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb364075 | [D-Trp12, Tyr34]-pTH (7-34) amide > 95% | 118102-98-0 | 1mg | $644.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb364075 | [D-Trp12, Tyr34]-pTH (7-34) amide > 95% | 118102-98-0 | 5mg | $1368.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb364075 | [D-Trp12, Tyr34]-pTH (7-34) amide > 95% | 118102-98-0 | 10mg | $2046.8 | 2021-12-16 | Buy |
(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) Chemical Properties,Uses,Production
Uses
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation[1][2].
in vivo
(D-Trp12,Tyr34)-pTH (7-34) amide (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels in hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung[3].
References
[1] Goldma ME, et, al. A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2. Endocrinology. 1988 Nov; 123(5): 2597-9. DOI:10.1210/endo-123-5-2597
[2] Pizurki L, et, al. Inhibition by (D-Trp12,Tyr34)bPTH(7-34)amide of PTH and PTHrP effects on Pi transport in renal cells. Am J Physiol. 1990 Aug; 259(2 Pt 2): F389-92. DOI:10.1152/ajprenal.1990.259.2.F389
[3] Kukreja SC, Inactivation by plasma may be responsible for lack of efficacy of parathyroid hormone antagonists in hypercalcemia of malignancy. Endocrinology. 1994 May; 134(5): 2184-8. DOI:10.1210/endo.134.5.8156920
(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) Preparation Products And Raw materials
Raw materials
Preparation Products
(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12739 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 995 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Nanjing TGpeptide | +86-13347807150 +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5221 | 58 |
| Moxin Chemicals | +8617320513646 | Anna@molcoo.com | China | 9790 | 58 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42957 | 64 |