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ChemicalBook >> CAS DataBase List >>N,N'-Bis(phenylmethyl)-1,2-ethanediamine

N,N'-Bis(phenylmethyl)-1,2-ethanediamine

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Structure
N,N'-Bis(phenylmethyl)-1,2-ethanediamine structure
CAS No.
140-28-3
Chemical Name:
N,N'-Bis(phenylmethyl)-1,2-ethanediamine
Synonyms
Dbed;BENZATHINE;N1,N2-Dibenzylethane-1,2-diaMine;Benzatin;Nsc5632;usafdo-53;USAF do-53;N,N'-DibenzyL;BENZATHINE 99%;enediamine Diacetate SaL
CBNumber:
CB6214137
Molecular Formula:
C16H20N2
Molecular Weight:
240.34
MDL Number:
MFCD00004771
MOL File:
140-28-3.mol
MSDS File:
SDS
Last updated:2024-10-28 16:48:35
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N,N'-Bis(phenylmethyl)-1,2-ethanediamine Properties

Melting point 23-25°C
Boiling point 195 °C4 mm Hg(lit.)
Density 1.02 g/mL at 25 °C(lit.)
refractive index n20/D 1.565(lit.)
Flash point >230 °F
storage temp. Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Water (Slightly)
form Solid
pka 9.15±0.19(Predicted)
color White to Off-White
Specific Gravity 1.025
Water Solubility Slightly soluble in water.
FreezingPoint 21.0 to 25.0 ℃
Sensitive Air Sensitive
Merck 14,1064
BRN 786668
CAS DataBase Reference 140-28-3(CAS DataBase Reference)
FDA UNII C659VZ7P7T
NIST Chemistry Reference 1,2-Ethanediamine, N,N'-bis(phenylmethyl)-(140-28-3)
EPA Substance Registry System 1,2-Ethanediamine, N,N'-bis(phenylmethyl)- (140-28-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
RIDADR  2927
WGK Germany  3
RTECS  KV3325000
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29215990
Toxicity LD50 orl-mus: 388 mg/kg CNCRA6 52,579,68
NFPA 704
1
3 0

N,N'-Bis(phenylmethyl)-1,2-ethanediamine price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D35201 N,N′-Dibenzylethylenediamine 97% 140-28-3 25g $94.9 2024-03-01 Buy
Sigma-Aldrich D35201 N,N′-Dibenzylethylenediamine 97% 140-28-3 100g $217 2024-03-01 Buy
TCI Chemical D1807 N,N'-Dibenzylethylenediamine >98.0%(GC)(T) 140-28-3 25mL $94 2024-03-01 Buy
TCI Chemical D1807 N,N'-Dibenzylethylenediamine >98.0%(GC)(T) 140-28-3 500mL $906 2024-03-01 Buy
Alfa Aesar L03540 N,N'-Dibenzylethylenediamine, 97% 140-28-3 25g $73.65 2024-03-01 Buy
Product number Packaging Price Buy
D35201 25g $94.9 Buy
D35201 100g $217 Buy
D1807 25mL $94 Buy
D1807 500mL $906 Buy
L03540 25g $73.65 Buy

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Chemical Properties,Uses,Production

Chemical Properties

light yellow liquid

Uses

N,N'-Dibenzylethylenediamine is an intermediate of cephalosporin and penicillin.

Definition

ChEBI: Benzathine is a diamine. It is a conjugate base of a benzathine(1+).

Synthesis Reference(s)

The Journal of Organic Chemistry, 55, p. 3209, 1990 DOI: 10.1021/jo00297a042

Safety Profile

Poison by ingestion,intraperitoneal, and parenteral routes. When heated todecomposition it emits toxic vapors of NOx.

Purification Methods

Dissolve DBED in acid, extract with toluene, basify, extract it with Et2O, dry over solid KOH, evaporate and fractionate it in vacuo. The diacetate crystallises from H2O by addition of EtOH and has m 111o (solubility in H2O is ~25%). The dihydrochloride has m 306-308o (from H2O) and the dipicrate has m 212o(dec) (from H2O). [Frost et al., J Am Chem Soc 71 3842 1949, Beilstein 12 H 1067, 12 III 2304.]

N,N'-Bis(phenylmethyl)-1,2-ethanediamine synthesis

100-52-7
107-15-3
140-28-3
Synthesis of N,N'-Bis(phenylmethyl)-1,2-ethanediamine from Benzaldehyde and Ethylenediamine

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Preparation Products And Raw materials

Raw materials

Preparation Products

2-(4-CHLOROPHENYL)-1,3-BIS(PHENYLMETHYL)-IMIDAZOLIDINE 1,3-dibenzyl-2-(4-methoxyphenyl)imidazolidine

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Suppliers

Global( 207)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Jinan Liheng Biotechnology Co., Ltd. 		15865262812 info@lihengpharm.com CHINA 938 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 13503 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17365 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Xiamen AmoyChem Co., Ltd 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Jinan Liheng Biotechnology Co., Ltd. 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
SIMAGCHEM CORP 		58

View Lastest Price from N,N'-Bis(phenylmethyl)-1,2-ethanediamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Benzathine pictures 2024-10-28 Benzathine
140-28-3
 US $1980.00-2500.00 / mg 10g TargetMol Chemicals Inc.
N,N'-Bis(phenylmethyl)-1,2-ethanediamine pictures 2022-09-07 N,N'-Bis(phenylmethyl)-1,2-ethanediamine
140-28-3
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
N,N'-Bis(phenylmethyl)-1,2-ethanediamine pictures 2022-08-18 N,N'-Bis(phenylmethyl)-1,2-ethanediamine
140-28-3
 US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
  • Benzathine pictures
  • Benzathine
    140-28-3
  • US $1980.00-2500.00 / mg
  • TargetMol Chemicals Inc.

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Spectrum

N,N'-Bis(phenylmethyl)-1,2-ethanediamine(140-28-3)MSN,N'-Bis(phenylmethyl)-1,2-ethanediamine(140-28-3)1HNMRN,N'-Bis(phenylmethyl)-1,2-ethanediamine(140-28-3)IR1N,N'-Bis(phenylmethyl)-1,2-ethanediamine(140-28-3)Raman

140-28-3(N,N'-Bis(phenylmethyl)-1,2-ethanediamine)Related Search:

Ethylenediamine ETHANE N,N'-Dibenzyl ethylenediamine diacetate N,N-dimethyl-N',N'-dibenzylethylenediamine N,N'-DIBENZYLETHYLENEDIAMINE, [1,2-BIS(BENZYLAMINO)ETHANE]
dibenzylethylenediamine-di-penicillin nn-Dibenzylethylenediamine2HCl,N,N'-DIBENZYLETHYLENEDIAMINE DIHYDROCHLORIDE BENZATHINE BENZYLPENICILLIN

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1,2-ETHANEDIAMINE,N,N''-BIS(PHENYLMETHYL)- N,N'-Bis(phenylmethyl)ethane-1,2-diamine Nsc5632 N,N'-DibenzylethylenediaMine Diacetate Salt N,N'-Dibenzylethylenediamine n,n’-bis(phenylmethyl)-2-ethanediamine n,n’-dibenzyl-ethylenediamin N,N'-Dibenzyl-1,2-ethanediamine N,N'-Dibenzyl-1,2-ethylenediamine N,N'-Dibenzyl-ethane-1,2-diamine USAF do-53 usafdo-53 1 2-BIS(BENZYLAMINO)ETHANE ETHYLENEDIAMINE-N N'-DIBENZYL N,N'-BIS(PHENYLMETHYL)-1,2-ETHANEDIAMINE N,N'-DIBENZYLETHYLENEDIAMINE N'N-DIBENZYL-ETHYLENEDIAMINE 1,2-di(benzylamino)ethane Benzathine~1,2-Bis(benzylamino)ethane N,N`-dibenzylethylendiamine BENZATHINE 99% 1 2-BIS(BENZYLAMINO)ETHANE 99% DBE, N,N'-Dibenzylethylenediamine N,N'-Dibenzylethylenediamine> enediamine Diacetate SaL N,N'-DibenzyL ETHYLENEDIAMINE-N,N'-DIBENZYL 140-28-3 N,N'-Bis(phenylmethyl)-1,2-ethanediamine ISO 9001：2015 REACH N1,N2-Dibenzylethane-1,2-diaMine Benzatin Dbed BENZATHINE N,N'-Dibenzylethylenediamine N,N'-Bis(phenylmethyl)-1,2-ethanediamine N,N'-dibenzylethane-1,2-diamine Enzastaurin Impurity 2 (Bisindolylmaleimide IV) 140-28-3 C6H5CH2NHCH2CH2NHCH2C6H5 C6H5CH2NHCH2CH2NHCH2C6H52CH3CO2H Organic Building Blocks Nitrogen Compounds Polyamines Building Blocks Nitrogen Compounds Organic Building Blocks Polyamines