6-Bromohexanoic acid
- CAS No.
- 4224-70-8
- Chemical Name:
- 6-Bromohexanoic acid
- Synonyms
- Hexanoic acid, 6-bromo-;6-bromohexanoate;ISBO-007;AKOS BB/0098;6-BroMhexine acid;6-bromo-hexanoicaci;6-BROMOCAPROIC ACID;6-BroMhexanoic acid;RARECHEM AL BO 0317;6-bromohexonic acid
- CBNumber:
- CB6221568
- Molecular Formula:
- C6H11BrO2
- Molecular Weight:
- 195.05
- MDL Number:
- MFCD00004422
- MOL File:
- 4224-70-8.mol
- MSDS File:
- SDS
| Melting point | 32-34 °C (lit.) |
|---|---|
| Boiling point | 165-170 °C/20 mmHg (lit.) |
| Density | 1.3996 (rough estimate) |
| refractive index | 1.4790 (estimate) |
| Flash point | 154 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | methanol: 0.1 g/mL, clear, colorless |
| pka | 4.72±0.10(Predicted) |
| form | Low Melting Crystals |
| color | White to light orange |
| BRN | 1749740 |
| InChIKey | NVRVNSHHLPQGCU-UHFFFAOYSA-N |
| LogP | 1.700 (est) |
| CAS DataBase Reference | 4224-70-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Hexanoic acid, 6-bromo-(4224-70-8) |
| EPA Substance Registry System | Hexanoic acid, 6-bromo- (4224-70-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45-28A | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Corrosive/Harmful | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159080 | |||||||||
| NFPA 704 |
|
6-Bromohexanoic acid price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 150452 | 6-Bromohexanoic acid 97% | 4224-70-8 | 5g | $36.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 150452 | 6-Bromohexanoic acid 97% | 4224-70-8 | 25g | $74 | 2024-03-01 | Buy |
| TCI Chemical | B1290 | 6-Bromohexanoic Acid >98.0%(GC)(T) | 4224-70-8 | 25g | $64 | 2024-03-01 | Buy |
| TCI Chemical | B1290 | 6-Bromohexanoic Acid >98.0%(GC)(T) | 4224-70-8 | 250g | $361 | 2024-03-01 | Buy |
| Alfa Aesar | A15761 | 6-Bromohexanoic acid, 98+% | 4224-70-8 | 25g | $65.65 | 2024-03-01 | Buy |
6-Bromohexanoic acid Chemical Properties,Uses,Production
Organic Intermediate
6-bromohexanoic acid(CAS:4224-70-8), also called 6-bromohexanoic acid or 6-bromo-hexanoic acid, is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. 6-Bromohexanoic acid is used in the preparation of N-acylsulfonamides, diarylthioethers and 2-lithio-1,3-dithian. It is widely used as an intermediate in organic synthesis. Here, we introduced a method for making this compound.
Chemical Properties
White to light orange low melting crystals
Uses
6-Bromohexanoic acid was used in the preparation of N-acylsulfonamides on treatment with tosyl isocyanate (189278) and alkyl ketones from alkyl iodides and metallic strontium. It was also used in the synthesis of anionic mitomycin C-dextran conjugate (MMC-D), 2-lithio-1,3-dithian and diaryl thioethers.
Uses
6-Bromohexanoic acid is used in the preparation of N-acylsulfonamides, diarylthioethers and 2-lithio-1,3-dithian. It is widely used as an intermediate in organic synthesis.
Uses
Employed in a direct preparation of N-acylsulfonamides on treatment with tosyl isocyanate (189278)1 and alkyl ketones from alkyl iodides and metallic strontium.2
Definition
ChEBI: 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It is functionally related to a hexanoic acid.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 5137, 1950 DOI: 10.1021/ja01167a091
Synthesis
The preparation method of the high purity 6-bromocaproic acid: the exsiccant bromize hydrogen gas is directly fed contain in the organic solvent of 6-caprolactone, exsiccant bromize hydrogen gas usage quantity is 6-caprolactone 1.0-2.0 doubly (mol ratio); Stir, ring-opening reaction takes place, temperature of reaction is 0 ℃ ~ 100 ℃, generates high purity 6-bromocaproic acid.
6-Bromohexanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hefei TianRui Pharmaceutical Chemical Co., Ltd. | +86-0551-68665055 +86-+86-18616906106 | sales@trywchem.com | China | 148 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3003 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12834 | 58 |
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| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3010 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20284 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| JingJiang Connect Chemical manufacturing Co., Ltd. | 0523-80501690 15252623102 | andy@katchemical.com | CHINA | 59 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Related articles
- Preparation of 6-Bromocaproic Acid
- 6-Bromohexanoic acid is used in the preparation of N-acylsulfonamides, diarylthioethers and 2-lithio-1,3-dithian. It is widely....
- Dec 20，2019
View Lastest Price from 6-Bromohexanoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-13 | 6-Bromohexanoic acid
4224-70-8
|
US $1.00 / KG | 1KG | 99% | 1000kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-10-28 | 6-Bromohexanoic acid
4224-70-8
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-10-25 | 6-Bromohexanoic acid
4224-70-8
|
US $20.00-2.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- 6-Bromohexanoic acid
4224-70-8
- US $1.00 / KG
- 99%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 6-Bromohexanoic acid
4224-70-8
- US $0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- 6-Bromohexanoic acid
4224-70-8
- US $20.00-2.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
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